Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling D Levy, AJ Kuo, Y Chang, U Schaefer, C Kitson, P Cheung, A Espejo, ... Nature immunology 12 (1), 29, 2011 | 292 | 2011 |
Nogo‐B receptor is necessary for cellular dolichol biosynthesis and protein N‐glycosylation KD Harrison, EJ Park, N Gao, A Kuo, JS Rush, CJ Waechter, MA Lehrman, ... The EMBO journal 30 (12), 2490-2500, 2011 | 128 | 2011 |
Lipid droplet biogenesis and function in the endothelium A Kuo, MY Lee, WC Sessa Circulation research 120 (8), 1289-1297, 2017 | 125 | 2017 |
Reticulon 4 is necessary for endoplasmic reticulum tubulation, STIM1-Orai1 coupling, and store-operated calcium entry L Jozsef, K Tashiro, A Kuo, EJ Park, A Skoura, S Albinsson, ... Journal of Biological Chemistry 289 (13), 9380-9395, 2014 | 86 | 2014 |
Caveolin-1 regulates lipid droplet metabolism in endothelial cells via autocrine prostacyclin–stimulated, cAMP-mediated lipolysis A Kuo, MY Lee, K Yang, RW Gross, WC Sessa Journal of Biological Chemistry 293 (3), 973-983, 2018 | 69 | 2018 |
Lysolipid receptor cross-talk regulates lymphatic endothelial junctions in lymph nodes Y Hisano, M Kono, A Cartier, E Engelbrecht, K Kano, K Kawakami, ... The Journal of experimental medicine 216 (7), 1582, 2019 | 57 | 2019 |
Sphingosine 1-phosphate receptor signaling establishes AP-1 gradients to allow for retinal endothelial cell specialization K Yanagida, E Engelbrecht, C Niaudet, B Jung, K Gaengel, K Holton, ... Developmental cell 52 (6), 779-793. e7, 2020 | 42 | 2020 |
Identification of ApoA4 as a sphingosine 1-phosphate chaperone in ApoM-and albumin-deficient mice H Obinata, A Kuo, Y Wada, S Swendeman, CH Liu, VA Blaho, R Nagumo, ... Journal of lipid research 60 (11), 1912-1921, 2019 | 38 | 2019 |
GSK-3β: a signaling pathway node modulating neural stem cell and endothelial cell interactions Q Li, M Michaud, S Canosa, A Kuo, JA Madri Angiogenesis 14, 173-185, 2011 | 38 | 2011 |
Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta E Engelbrecht, MV Levesque, L He, M Vanlandewijck, A Nitzsche, H Niazi, ... Elife 9, e52690, 2020 | 35 | 2020 |
Endothelial-specific loss of sphingosine-1-phosphate receptor 1 increases vascular permeability and exacerbates bleomycin-induced pulmonary fibrosis RS Knipe, JJ Spinney, EA Abe, CK Probst, A Franklin, A Logue, ... American Journal of Respiratory Cell and Molecular Biology 66 (1), 38-52, 2022 | 27 | 2022 |
Stimulation of caveolin-1 signaling improves arteriovenous fistula patency T Hashimoto, T Isaji, H Hu, K Yamamoto, H Bai, JM Santana, A Kuo, ... Arteriosclerosis, thrombosis, and vascular biology 39 (4), 754-764, 2019 | 24 | 2019 |
SETD6 lysine methylation of RelA couples GLP activity at chromatin to tonic repression of NF-κB signaling D Levy, AJ Kuo, Y Chang, U Schaefer, C Kitson, P Cheung, A Espejo, ... Nature immunology 12 (1), 29, 2011 | 15 | 2011 |
Pazopanib ameliorates acute lung injuries via inhibition of MAP3K2 and MAP3K3 Q Yuan, A Basit, W Liang, R Qu, Y Luan, C Ren, A Li, X Xu, X Liu, C Yang, ... Science translational medicine 13 (591), eabc2499, 2021 | 13 | 2021 |
Therapeutic activation of endothelial sphingosine‐1‐phosphate receptor 1 by chaperone‐bound S1P suppresses proliferative retinal neovascularization C Niaudet, B Jung, A Kuo, S Swendeman, E Bull, T Seno, R Crocker, Z Fu, ... EMBO Molecular Medicine 15 (5), e16645, 2023 | 10 | 2023 |
Murine endothelial serine palmitoyltransferase 1 (SPTLC1) is required for vascular development and systemic sphingolipid homeostasis A Kuo, A Checa, C Niaudet, B Jung, Z Fu, CE Wheelock, SA Singh, ... Elife 11, e78861, 2022 | 8 | 2022 |
Dynamic metabolism of endothelial triglycerides protects against atherosclerosis in mice NE Boutagy, A Gamez-Mendez, JWM Fowler, H Zhang, BK Chaube, ... The Journal of Clinical Investigation 134 (4), 2024 | 6 | 2024 |
DOCK4 regulation of Rho GTPases mediates pulmonary vascular barrier function P Yazbeck, X Cullere, P Bennett, V Yajnik, H Wang, K Kawada, VM Davis, ... Arteriosclerosis, thrombosis, and vascular biology 42 (7), 886-902, 2022 | 3 | 2022 |
Sphingosine kinases protect murine embryonic stem cells from sphingosine-induced cell cycle arrest S Pandey, KM Banks, R Kumar, A Kuo, D Wen, T Hla, T Evans Stem Cells 38 (5), 613-623, 2020 | 3 | 2020 |
Regulation of cellular and systemic sphingolipid homeostasis A Kuo, T Hla Nature Reviews Molecular Cell Biology, 1-20, 2024 | 2 | 2024 |