MicroRNA silencing for cancer therapy targeted to the tumour microenvironment CJ Cheng, R Bahal, IA Babar, Z Pincus, F Barrera, C Liu, A Svoronos, ... Nature 518 (7537), 107-110, 2015 | 859 | 2015 |
Genetic instability induced by the tumor microenvironment TY Reynolds, S Rockwell, PM Glazer Cancer research 56 (24), 5754-5757, 1996 | 580 | 1996 |
2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity PL Sulkowski, CD Corso, ND Robinson, SE Scanlon, KR Purshouse, ... Science translational medicine 9 (375), eaal2463, 2017 | 524 | 2017 |
MicroRNA regulation of DNA repair gene expression in hypoxic stress ME Crosby, R Kulshreshtha, M Ivan, PM Glazer Cancer research 69 (3), 1221-1229, 2009 | 517 | 2009 |
Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local breast cancer recurrence after lumpectomy and radiation BC Turner, BG Haffty, L Narayanan, J Yuan, PA Havre, AA Gumbs, ... Cancer research 57 (15), 3079-3083, 1997 | 429 | 1997 |
Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells RS Bindra, PJ Schaffer, A Meng, J Woo, K Måseide, ME Roth, P Lizardi, ... Molecular and cellular biology, 2004 | 420 | 2004 |
Mutagenesis in mammalian cells induced by triple helix formation and transcription-coupled repair G Wang, MM Seidman, PM Glazer Science 271 (5250), 802-805, 1996 | 399 | 1996 |
Hypoxia-induced down-regulation of BRCA1 expression by E2Fs RS Bindra, SL Gibson, A Meng, U Westermark, M Jasin, AJ Pierce, ... Cancer research 65 (24), 11597-11604, 2005 | 389 | 2005 |
Outcome of conservatively managed early-onset breast cancer by BRCA1/2 status BG Haffty, E Harrold, AJ Khan, P Pathare, TE Smith, BC Turner, ... The Lancet 359 (9316), 1471-1477, 2002 | 389 | 2002 |
MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU E Favaro, A Ramachandran, R McCormick, H Gee, C Blancher, M Crosby, ... PloS one 5 (4), e10345, 2010 | 358 | 2010 |
Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance N Chan, M Koritzinsky, H Zhao, R Bindra, PM Glazer, S Powell, ... Cancer research 68 (2), 605-614, 2008 | 355 | 2008 |
Decreased Expression of the DNA Mismatch Repair Gene Mlh1 under Hypoxic Stress in Mammalian Cells VT Mihaylova, RS Bindra, J Yuan, D Campisi, L Narayanan, R Jensen, ... Molecular and cellular biology 23 (9), 3265-3273, 2003 | 338 | 2003 |
Specific mutations induced by triplex-forming oligonucleotides in mice KM Vasquez, L Narayanan, PM Glazer Science 290 (5491), 530-533, 2000 | 319 | 2000 |
Triplex DNA: fundamentals, advances, and potential applications for gene therapy PP Chan, PM Glazer Journal of Molecular Medicine 75, 267-282, 1997 | 317 | 1997 |
Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation G Wang, DD Levy, MM Seidman, PMG Glazer Molecular and cellular biology, 1995 | 298 | 1995 |
p53 inactivation by HPV16 E6 results in increased mutagenesis in human cells PA Havre, J Yuan, L Hedrick, KR Cho, PM Glazer Cancer research 55 (19), 4420-4424, 1995 | 295 | 1995 |
Diminished DNA repair and elevated mutagenesis in mammalian cells exposed to hypoxia and low pH J Yuan, L Narayanan, S Rockwell, PM Glazer Cancer research 60 (16), 4372-4376, 2000 | 284 | 2000 |
Targeted gene knockout mediated by triple helix forming oligonucleotides A Majumdar, A Khorlin, N Dyatkina, FLM Lin, J Powell, J Liu, Z Fei, ... Nature genetics 20 (2), 212-214, 1998 | 257 | 1998 |
Expression of AP-2 transcription factors in human breast cancer correlates with the regulation of multiple growth factor signalling pathways BC Turner, J Zhang, AA Gumbs, MG Maher, L Kaplan, D Carter, ... Cancer research 58 (23), 5466-5472, 1998 | 252 | 1998 |
Inhibition of poly (ADP-ribose) polymerase down-regulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130 DC Hegan, Y Lu, GC Stachelek, ME Crosby, RS Bindra, PM Glazer Proceedings of the National Academy of Sciences 107 (5), 2201-2206, 2010 | 251 | 2010 |