Adaptation of Sindbis virus to BHK cells selects for use of heparan sulfate as an attachment receptor WB Klimstra, KD Ryman, RE Johnston Journal of virology 72 (9), 7357-7366, 1998 | 467 | 1998 |
Yellow fever: a reemerging threat CL Gardner, KD Ryman Clinics in laboratory medicine 30 (1), 237-260, 2010 | 363 | 2010 |
DC-SIGN and L-SIGN can act as attachment receptors for alphaviruses and distinguish between mosquito cell-and mammalian cell-derived viruses WB Klimstra, EM Nangle, MS Smith, AD Yurochko, KD Ryman Journal of virology 77 (22), 12022-12032, 2003 | 327 | 2003 |
Alpha/beta interferon protects adult mice from fatal Sindbis virus infection and is an important determinant of cell and tissue tropism KD Ryman, WB Klimstra, KB Nguyen, CA Biron, RE Johnston Journal of virology 74 (7), 3366-3378, 2000 | 311 | 2000 |
Identification and characterization of interferon-induced proteins that inhibit alphavirus replication Y Zhang, CW Burke, KD Ryman, WB Klimstra Journal of virology 81 (20), 11246-11255, 2007 | 298 | 2007 |
RNA viruses can hijack vertebrate microRNAs to suppress innate immunity DW Trobaugh, CL Gardner, C Sun, AD Haddow, E Wang, E Chapnik, ... Nature 506 (7487), 245-248, 2014 | 238 | 2014 |
Host responses to alphavirus infection KD Ryman, WB Klimstra Immunological reviews 225 (1), 27-45, 2008 | 199 | 2008 |
Mosquito saliva serine protease enhances dissemination of dengue virus into the mammalian host MJ Conway, AM Watson, TM Colpitts, SM Dragovic, Z Li, P Wang, ... Journal of virology 88 (1), 164-175, 2014 | 162 | 2014 |
Eastern and Venezuelan equine encephalitis viruses differ in their ability to infect dendritic cells and macrophages: impact of altered cell tropism on pathogenesis CL Gardner, CW Burke, MZ Tesfay, PJ Glass, WB Klimstra, KD Ryman Journal of virology 82 (21), 10634-10646, 2008 | 154 | 2008 |
A mouse model for studying viscerotropic disease caused by yellow fever virus infection KC Meier, CL Gardner, MV Khoretonenko, WB Klimstra, KD Ryman PLoS pathogens 5 (10), e1000614, 2009 | 148 | 2009 |
Heparan sulfate binding by natural eastern equine encephalitis viruses promotes neurovirulence CL Gardner, GD Ebel, KD Ryman, WB Klimstra Proceedings of the National Academy of Sciences 108 (38), 16026-16031, 2011 | 137 | 2011 |
Interferon-alpha/beta deficiency greatly exacerbates arthritogenic disease in mice infected with wild-type chikungunya virus but not with the cell culture-adapted live … CL Gardner, CW Burke, ST Higgs, WB Klimstra, KD Ryman Virology 425 (2), 103-112, 2012 | 135 | 2012 |
Stable, high-level expression of reporter proteins from improved alphavirus expression vectors to track replication and dissemination during encephalitic and arthritogenic disease C Sun, CL Gardner, AM Watson, KD Ryman, WB Klimstra Journal of virology 88 (4), 2035-2046, 2014 | 126 | 2014 |
Infection of neonatal mice with sindbis virus results in a systemic inflammatory response syndrome WB Klimstra, KD Ryman, KA Bernard, KB Nguyen, CA Biron, RE Johnston Journal of virology 73 (12), 10387-10398, 1999 | 116 | 1999 |
Effects of PKR/RNase L-dependent and alternative antiviral pathways on alphavirus replication and pathogenesis KD Ryman, LJ White, RE Johnston, WB Klimstra Viral immunology 15 (1), 53-76, 2002 | 115 | 2002 |
Sindbis virus translation is inhibited by a PKR/RNase L-independent effector induced by alpha/beta interferon priming of dendritic cells KD Ryman, KC Meier, EM Nangle, SL Ragsdale, NL Korneeva, ... Journal of virology 79 (3), 1487-1499, 2005 | 111 | 2005 |
Deliberate attenuation of chikungunya virus by adaptation to heparan sulfate-dependent infectivity: a model for rational arboviral vaccine design CL Gardner, J Hritz, C Sun, DL Vanlandingham, TY Song, E Ghedin, ... PLoS neglected tropical diseases 8 (2), e2719, 2014 | 107 | 2014 |
Conformational changes in Sindbis virions resulting from exposure to low pH and interactions with cells suggest that cell penetration may occur at the cell surface in the … AM Paredes, D Ferreira, M Horton, A Saad, H Tsuruta, R Johnston, ... Virology 324 (2), 373-386, 2004 | 107 | 2004 |
Heparan sulfate binding can contribute to the neurovirulence of neuroadapted and nonneuroadapted Sindbis viruses KD Ryman, CL Gardner, CW Burke, KC Meier, JM Thompson, ... Journal of virology 81 (7), 3563-3573, 2007 | 90 | 2007 |
Comparison of the live attenuated yellow fever vaccine 17D-204 strain to its virulent parental strain Asibi by deep sequencing A Beck, RB Tesh, TG Wood, SG Widen, KD Ryman, ADT Barrett The Journal of infectious diseases 209 (3), 334-344, 2014 | 86 | 2014 |