关注
Jeffrey W. Tyner
Jeffrey W. Tyner
Professor of Medicine
在 ohsu.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
The 5th edition of the World Health Organization classification of haematolymphoid tumours: myeloid and histiocytic/dendritic neoplasms
JD Khoury, E Solary, O Abla, Y Akkari, R Alaggio, JF Apperley, R Bejar, ...
leukemia 36 (7), 1703-1719, 2022
19572022
AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance
T O'Hare, WC Shakespeare, X Zhu, CA Eide, VM Rivera, F Wang, ...
Cancer cell 16 (5), 401-412, 2009
14342009
Functional genomic landscape of acute myeloid leukaemia
JW Tyner, CE Tognon, D Bottomly, B Wilmot, SE Kurtz, SL Savage, ...
Nature 562 (7728), 526-531, 2018
10812018
CAL-101, a p110δ selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability
BJ Lannutti, SA Meadows, SEM Herman, A Kashishian, B Steiner, ...
Blood, The Journal of the American Society of Hematology 117 (2), 591-594, 2011
8752011
Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease
EY Kim, JT Battaile, AC Patel, Y You, E Agapov, MH Grayson, LA Benoit, ...
Nature medicine 14 (6), 633-640, 2008
6242008
Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML
JE Maxson, J Gotlib, DA Pollyea, AG Fleischman, A Agarwal, CA Eide, ...
New England Journal of Medicine 368 (19), 1781-1790, 2013
6142013
Integrated proteogenomic characterization of clear cell renal cell carcinoma
DJ Clark, SM Dhanasekaran, F Petralia, J Pan, X Song, Y Hu, ...
Cell 179 (4), 964-983. e31, 2019
4712019
Proteogenomic and metabolomic characterization of human glioblastoma
LB Wang, A Karpova, MA Gritsenko, JE Kyle, S Cao, Y Li, D Rykunov, ...
Cancer cell 39 (4), 509-528. e20, 2021
4132021
Activating alleles of JAK3 in acute megakaryoblastic leukemia
DK Walters, T Mercher, TL Gu, T O'Hare, JW Tyner, M Loriaux, VL Goss, ...
Cancer cell 10 (1), 65-75, 2006
3662006
Proteogenomic characterization of endometrial carcinoma
Y Dou, EA Kawaler, DC Zhou, MA Gritsenko, C Huang, L Blumenberg, ...
Cell 180 (4), 729-748. e26, 2020
3422020
CCL5-CCR5 interaction provides antiapoptotic signals for macrophage survival during viral infection
JW Tyner, O Uchida, N Kajiwara, EY Kim, AC Patel, MP O'Sullivan, ...
Nature medicine 11 (11), 1180-1187, 2005
3322005
Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals
JW Tyner, EY Kim, K Ide, MR Pelletier, WT Roswit, JD Morton, JT Battaile, ...
The Journal of clinical investigation 116 (2), 309-321, 2006
3062006
CSF3R T618I is a highly prevalent and specific mutation in chronic neutrophilic leukemia
A Pardanani, TL Lasho, RR Laborde, M Elliott, CA Hanson, RA Knudson, ...
Leukemia 27 (9), 1870-1873, 2013
2792013
CYT387, a novel JAK2 inhibitor, induces hematologic responses and normalizes inflammatory cytokines in murine myeloproliferative neoplasms
JW Tyner, TG Bumm, J Deininger, L Wood, KJ Aichberger, MM Loriaux, ...
Blood, The Journal of the American Society of Hematology 115 (25), 5232-5240, 2010
2712010
The TP53 apoptotic network is a primary mediator of resistance to BCL2 inhibition in AML cells
T Nechiporuk, SE Kurtz, O Nikolova, T Liu, CL Jones, A D'Alessandro, ...
Cancer discovery 9 (7), 910-925, 2019
2682019
Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma
C Huang, L Chen, SR Savage, RV Eguez, Y Dou, Y Li, ...
Cancer cell 39 (3), 361-379. e16, 2021
2322021
Identification of interleukin-1 by functional screening as a key mediator of cellular expansion and disease progression in acute myeloid leukemia
A Carey, DK Edwards, CA Eide, L Newell, E Traer, BC Medeiros, ...
Cell reports 18 (13), 3204-3218, 2017
2302017
Ex vivo drug response profiling detects recurrent sensitivity patterns in drug-resistant acute lymphoblastic leukemia
V Frismantas, MP Dobay, A Rinaldi, J Tchinda, SH Dunn, J Kunz, ...
Blood, The Journal of the American Society of Hematology 129 (11), e26-e37, 2017
2212017
The new genetics of chronic neutrophilic leukemia and atypical CML: implications for diagnosis and treatment
J Gotlib, JE Maxson, TI George, JW Tyner
Blood, The Journal of the American Society of Hematology 122 (10), 1707-1711, 2013
2012013
Targeting super-enhancer-associated oncogenes in oesophageal squamous cell carcinoma
YY Jiang, DC Lin, A Mayakonda, M Hazawa, LW Ding, WW Chien, L Xu, ...
Gut 66 (8), 1358-1368, 2017
1952017
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