关注
Grant O'Connell
Grant O'Connell
Assistant Professor, Case Western Reserve University
在 case.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Circulating extracellular DNA levels are acutely elevated in ischaemic stroke and associated with innate immune system activation
GC O’Connell, AB Petrone, CS Tennant, N Lucke-Wold, Y Kabbani, ...
Brain Injury 31 (10), 1369-1375, 2017
712017
Machine-learning approach identifies a pattern of gene expression in peripheral blood that can accurately detect ischaemic stroke
GC O’Connell, AB Petrone, MB Treadway, CS Tennant, N Lucke-Wold, ...
NPJ Genomic Medicine 1 (1), 1-9, 2016
542016
The role of arginase 1 in post-stroke immunosuppression and ischemic stroke severity
AB Petrone, GC O’Connell, MD Regier, PD Chantler, JW Simpkins, ...
Translational stroke research 7, 103-110, 2016
492016
High interspecimen variability in nucleic acid extraction efficiency necessitates the use of spike-in control for accurate qPCR-based measurement of plasma cell-free DNA levels
GC O’Connell, PD Chantler, TL Barr
Laboratory Medicine 48 (4), 332-338, 2017
482017
Use of high-sensitivity digital ELISA improves the diagnostic performance of circulating brain-specific proteins for detection of traumatic brain injury during triage
GC O’Connell, ML Alder, CG Smothers, CH Still, AR Webel, SM Moore
Neurological research 42 (4), 346-353, 2020
372020
Peripheral blood AKAP7 expression as an early marker for lymphocyte-mediated post-stroke blood brain barrier disruption
GC O’Connell, MB Treadway, AB Petrone, CS Tennant, N Lucke-Wold, ...
Scientific Reports 7 (1), 1172, 2017
362017
Monocyte-lymphocyte cross-communication via soluble CD163 directly links innate immune system activation and adaptive immune system suppression following ischemic stroke
GC O’Connell, CS Tennant, N Lucke-Wold, Y Kabbani, AR Tarabishy, ...
Scientific reports 7 (1), 12940, 2017
352017
Bioinformatic analysis of brain-specific miRNAs for identification of candidate traumatic brain injury blood biomarkers
GC O’Connell, CG Smothers, C Winkelman
Brain injury 34 (7), 965-974, 2020
332020
Stroke-associated pattern of gene expression previously identified by machine-learning is diagnostically robust in an independent patient population
GC O'Connell, PD Chantler, TL Barr
Genomics data 14, 47-52, 2017
322017
Neuro biomarker levels measured with high-sensitivity digital ELISA differ between serum and plasma
GC O'Connell, ML Alder, AR Webel, SM Moore
Bioanalysis 11 (22), 2087-2094, 2019
282019
Interleukin-15 directly stimulates pro-oxidative gene expression in skeletal muscle in-vitro via a mechanism that requires interleukin-15 receptor alpha
GC O'Connell, EE Pistilli
Biochemical and biophysical research communications 458 (3), 614-619, 2015
282015
Diagnostic accuracy of blood biomarkers for Alzheimer’s disease and amnestic mild cognitive impairment: A meta-analysis
YR Chen, CS Liang, H Chu, J Voss, XL Kang, G O'Connell, HJ Jen, D Liu, ...
Ageing Research Reviews 71, 101446, 2021
222021
Shifts in leukocyte counts drive the differential expression of transcriptional stroke biomarkers in whole blood
GC O’Connell, MB Treadway, CS Tennant, N Lucke-Wold, PD Chantler, ...
Translational stroke research 10, 26-35, 2019
202019
Diagnosis of ischemic stroke using circulating levels of brain-specific proteins measured via high-sensitivity digital ELISA
GC O'Connell, ML Alder, CG Smothers, CH Still, AR Webel, SM Moore
Brain research 1739, 146861, 2020
192020
Muscle-specific deletion of exons 2 and 3 of the IL15RA gene in mice: effects on contractile properties of fast and slow muscles
G O'Connell, G Guo, J Stricker, LBS Quinn, A Ma, EE Pistilli
Journal of Applied Physiology 118 (4), 437-448, 2015
192015
Leukocyte dynamics influence reference gene stability in whole blood: data-driven qRT-PCR normalization is a robust alternative for measurement of transcriptional biomarkers
GC O’Connell, MB Treadway, AB Petrone, CS Tennant, N Lucke-Wold, ...
Laboratory Medicine 48 (4), 346-356, 2017
162017
Analysis of early stroke-induced changes in circulating leukocyte counts using transcriptomic deconvolution
GC O’Connell, JHC Chang
Translational neuroscience 9 (1), 161-166, 2018
142018
IL-15Rα deficiency in skeletal muscle alters respiratory function and the proteome of mitochondrial subpopulations independent of changes to the mitochondrial genome
GC O'Connell, C Nichols, G Guo, TL Croston, D Thapa, JM Hollander, ...
Mitochondrion 25, 87-97, 2015
132015
Large-scale informatic analysis to algorithmically identify blood biomarkers of neurological damage
GC O’Connell, ML Alder, CG Smothers, JHC Chang
Proceedings of the National Academy of Sciences 117 (34), 20764-20775, 2020
102020
Loss of adipocyte VEGF impairs endurance exercise capacity in mice
NJ Zachwieja, GC O’Connell, JC Stricker, J Allen, L Vona-Davis, R Bryner, ...
Medicine and science in sports and exercise 47 (11), 2329, 2015
102015
系统目前无法执行此操作,请稍后再试。
文章 1–20