RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself BJ Liddicoat, R Piskol, AM Chalk, G Ramaswami, M Higuchi, JC Hartner, ... Science 349 (6252), 1115-1120, 2015 | 798 | 2015 |
A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer F de Sousa e Melo, AV Kurtova, JM Harnoss, N Kljavin, JD Hoeck, J Hung, ... Nature 543 (7647), 676-680, 2017 | 610 | 2017 |
Dynamic landscape and regulation of RNA editing in mammals MH Tan, Q Li, R Shanmugam, R Piskol, J Kohler, AN Young, KI Liu, ... Nature 550 (7675), 249-254, 2017 | 552 | 2017 |
Reliable identification of genomic variants from RNA-seq data R Piskol, G Ramaswami, JB Li The American Journal of Human Genetics 93 (4), 641-651, 2013 | 394 | 2013 |
Identifying RNA editing sites using RNA sequencing data alone G Ramaswami, R Zhang, R Piskol, LP Keegan, P Deng, MA O'connell, ... Nature methods 10 (2), 128-132, 2013 | 391 | 2013 |
Accurate identification of human Alu and non-Alu RNA editing sites G Ramaswami, W Lin, R Piskol, MH Tan, C Davis, JB Li Nature methods 9 (6), 579-581, 2012 | 381 | 2012 |
Comment on “Widespread RNA and DNA Sequence Differences in the Human Transcriptome” W Lin, R Piskol, MH Tan, JB Li Science 335 (6074), 1302-1302, 2012 | 310* | 2012 |
Blockade of the phagocytic receptor MerTK on tumor-associated macrophages enhances P2X7R-dependent STING activation by tumor-derived cGAMP Y Zhou, M Fei, G Zhang, WC Liang, WY Lin, Y Wu, R Piskol, J Ridgway, ... Immunity 52 (2), 357-373. e9, 2020 | 281 | 2020 |
CD3 bispecific antibody–induced cytokine release is dispensable for cytotoxic T cell activity J Li, R Piskol, R Ybarra, YJJ Chen, J Li, D Slaga, M Hristopoulos, R Clark, ... Science translational medicine 11 (508), eaax8861, 2019 | 142 | 2019 |
A cell identity switch allows residual BCC to survive Hedgehog pathway inhibition B Biehs, GJP Dijkgraaf, R Piskol, B Alicke, S Boumahdi, F Peale, ... Nature 562 (7727), 429-433, 2018 | 137 | 2018 |
ARAF mutations confer resistance to the RAF inhibitor belvarafenib in melanoma I Yen, F Shanahan, J Lee, YS Hong, SJ Shin, AR Moore, J Sudhamsu, ... Nature 594 (7863), 418-423, 2021 | 83 | 2021 |
Functional characterization of SMARCA4 variants identified by targeted exome-sequencing of 131,668 cancer patients TM Fernando, R Piskol, R Bainer, ES Sokol, SE Trabucco, Q Zhang, ... Nature communications 11 (1), 5551, 2020 | 80 | 2020 |
Lack of evidence for existence of noncanonical RNA editing R Piskol, Z Peng, J Wang, JB Li Nature biotechnology 31 (1), 19-20, 2013 | 76 | 2013 |
Stem cell plasticity enables hair regeneration following Lgr5+ cell loss JD Hoeck, B Biehs, AV Kurtova, NM Kljavin, F de Sousa e Melo, B Alicke, ... Nature cell biology 19 (6), 666-676, 2017 | 74 | 2017 |
Allelic expression of deleterious protein-coding variants across human tissues KR Kukurba, R Zhang, X Li, KS Smith, DA Knowles, M How Tan, R Piskol, ... PLoS genetics 10 (5), e1004304, 2014 | 73 | 2014 |
A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells AH Nile, F de Sousa e Melo, S Mukund, R Piskol, S Hansen, L Zhou, ... Nature chemical biology 14 (6), 582-590, 2018 | 66 | 2018 |
Adenosine-to-inosine RNA editing by ADAR1 is essential for normal murine erythropoiesis BJ Liddicoat, JC Hartner, R Piskol, G Ramaswami, AM Chalk, ... Experimental hematology 44 (10), 947-963, 2016 | 63 | 2016 |
A clinically applicable gene-expression classifier reveals intrinsic and extrinsic contributions to consensus molecular subtypes in primary and metastatic colon cancer R Piskol, L Huw, I Sergin, C Kljin, Z Modrusan, D Kim, N Kljavin, R Tam, ... Clinical Cancer Research 25 (14), 4431-4442, 2019 | 50 | 2019 |
Identifying transcriptional programs underlying cancer drug response with TraCe-seq MT Chang, F Shanahan, TTT Nguyen, ST Staben, L Gazzard, S Yamazoe, ... Nature Biotechnology 40 (1), 86-93, 2022 | 34 | 2022 |
An anti-GDNF family receptor alpha 1 (GFRA1) antibody–drug conjugate for the treatment of hormone receptor–positive breast cancer S Bhakta, LM Crocker, Y Chen, M Hazen, MM Schutten, D Li, C Kuijl, ... Molecular cancer therapeutics 17 (3), 638-649, 2018 | 32 | 2018 |