Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and … JB de Haan, C Bladier, P Griffiths, M Kelner, RD O'Shea, NS Cheung, ... Journal of Biological Chemistry 273 (35), 22528-22536, 1998 | 602 | 1998 |
Transporters for L‐glutamate: An update on their molecular pharmacology and pathological involvement PM Beart, RD O'Shea British journal of pharmacology 150 (1), 5-17, 2007 | 498 | 2007 |
Roles and regulation of glutamate transporters in the central nervous system RD O'shea Clinical and Experimental Pharmacology and Physiology 29 (11), 1018-1023, 2002 | 211 | 2002 |
Modulation of hypothalamic–pituitary–adrenal function by transgenic expression of interleukin-6 in the CNS of mice J Raber, RD O’Shea, FE Bloom, IL Campbell Journal of Neuroscience 17 (24), 9473-9480, 1997 | 111 | 1997 |
Regulation of σ‐receptors: high‐and low‐affinity agonist states, GTP shifts, and up‐regulation by rimcazole and 1, 3‐di (2‐tolyl) guanidine PM Beart, RD O'Shea, DT Manallack Journal of neurochemistry 53 (3), 779-788, 1989 | 105 | 1989 |
Preproneuropeptide Y messenger ribonucleic acid in the hypothalamic arcuate nucleus of the rat is increased by food deprivation or dehydration RD O'Shea, AL Gundlach Journal of Neuroendocrinology 3 (1), 11-14, 1991 | 96 | 1991 |
Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response EA Monson, KM Crosse, M Duan, W Chen, RD O’shea, LM Wakim, ... Nature Communications 12 (1), 4303, 2021 | 88 | 2021 |
The Rho kinase inhibitor Fasudil up‐regulates astrocytic glutamate transport subsequent to actin remodelling in murine cultured astrocytes CL Lau, RD O'shea, BV Broberg, L Bischof, PM Beart British journal of pharmacology 163 (3), 533-545, 2011 | 83 | 2011 |
c-jun expression in substantia nigra neurons following striatal 6-hydroxydopamine lesions in the rat R Jenkins, R O'shea, KL Thomas, SP Hunt Neuroscience 53 (2), 447-455, 1993 | 83 | 1993 |
Food or water deprivation modulate nitric oxide synthase (NOS) activity and gene expression in rat hypothalamic neurones: correlation with neurosecretory activity? RD O'shea, AL Gundlach Journal of neuroendocrinology 8 (6), 417-425, 1996 | 79 | 1996 |
Effects of lipopolysaccharide on glial phenotype and activity of glutamate transporters: evidence for delayed up-regulation and redistribution of GLT-1 RD O'Shea, CL Lau, MC Farso, S Diwakarla, CJ Zagami, BB Svendsen, ... Neurochemistry international 48 (6-7), 604-610, 2006 | 67 | 2006 |
Transcriptomic profiling of astrocytes treated with the Rho kinase inhibitor Fasudil reveals cytoskeletal and pro‐survival responses CL Lau, VM Perreau, MJ Chen, HS Cate, D Merlo, NS Cheung, ... Journal of cellular physiology 227 (3), 1199-1211, 2012 | 57 | 2012 |
Hypoxic preconditioning in neonatal rat brain involves regulation of excitatory amino acid transporter 2 and estrogen receptor alpha H Cimarosti, NM Jones, RD O'Shea, DV Pow, C Salbego, PM Beart Neuroscience letters 385 (1), 52-57, 2005 | 56 | 2005 |
Astrocyte mGlu2/3-mediated cAMP potentiation is calcium sensitive: studies in murine neuronal and astrocyte cultures RX Moldrich, K Apricó, S Diwakarla, RD O’Shea, PM Beart Neuropharmacology 43 (2), 189-203, 2002 | 52 | 2002 |
Evidence for heterogenous glycine domains but conserved multiple states of the excitatory amino acid recognition site of the NMDA receptor: regional binding studies with [3H … RD O'shea, DT Manallack, EL Conway, LD Mercer, PM Beart Experimental brain research 86, 652-662, 1991 | 50 | 1991 |
Oxidative and excitotoxic insults exert differential effects on spinal motoneurons and astrocytic glutamate transporters: Implications for the role of astrogliosis in … CJ Zagami, PM Beart, N Wallis, P Nagley, RD O'shea Glia 57 (2), 119-135, 2009 | 47 | 2009 |
Evidence group I mGluR drugs modulate the activation profile of lipopolysaccharide-exposed microglia in culture MC Farso, RD O’Shea, PM Beart Neurochemical research 34, 1721-1728, 2009 | 44 | 2009 |
The role of immediate early genes in the regeneration of the central nervous system C De Felipe, R Jenkins, R O'Shea, TS Williams, SP Hunt Advances in neurology 59, 263-271, 1993 | 44 | 1993 |
Links between L-glutamate transporters, Na+/K+-ATPase and cytoskeleton in astrocytes: evidence following inhibition with rottlerin RK Sheean, CL Lau, YS Shin, RD O’Shea, PM Beart Neuroscience 254, 335-346, 2013 | 43 | 2013 |
Regulation of glutamate transporters in astrocytes: evidence for a relationship between transporter expression and astrocytic phenotype CJ Zagami, RD O’shea, CL Lau, SS Cheema, PM Beart Neurotoxicity research 7, 143-149, 2005 | 41 | 2005 |