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Matthias Bütikofer
Matthias Bütikofer
在 ethz.ch 的电子邮件经过验证
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Large-scale recombinant production of the SARS-CoV-2 proteome for high-throughput and structural biology applications
N Altincekic, SM Korn, NS Qureshi, M Dujardin, M Ninot-Pedrosa, R Abele, ...
Frontiers in molecular biosciences 8, 653148, 2021
452021
Identification of natural products inhibiting SARS-CoV-2 by targeting viral proteases: a combined in silico and in vitro approach
A Wasilewicz, B Kirchweger, D Bojkova, MJ Abi Saad, J Langeder, ...
Journal of Natural Products 86 (2), 264-275, 2023
232023
Ultrafast Fragment Screening Using Photo-Hyperpolarized (CIDNP) NMR
F Torres, M Bütikofer, GR Stadler, A Renn, H Kadavath, R Bobrovs, ...
Journal of the American Chemical Society 145 (22), 12066-12080, 2023
222023
Protein structure determination in human cells by in-cell NMR and a reporter system to optimize protein delivery or transexpression
JA Gerez, NC Prymaczok, H Kadavath, D Ghosh, M Bütikofer, ...
Communications Biology 5 (1), 1322, 2022
182022
Comprehensive fragment screening of the SARS‐CoV‐2 proteome explores novel chemical space for drug development
H Berg, MA Wirtz Martin, N Altincekic, I Alshamleh, J Kaur Bains, ...
Angewandte Chemie International Edition 61 (46), e202205858, 2022
182022
Fragment Screening and Fast Micromolar Detection on a Benchtop NMR Spectrometer Boosted by Photoinduced Hyperpolarization
GR Stadler, TF Segawa, M Bütikofer, V Decker, S Loss, B Czarniecki, ...
Angewandte Chemie International Edition 62 (40), e202308692, 2023
82023
High-Mass Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry for Absolute Quantitation of Noncovalent Protein–Protein Binding Interactions
N Wu, L Jiao, M Bütikofer, Z Zeng, R Zenobi
Analytical Chemistry 93 (31), 10982-10989, 2021
72021
Carbonyl sulfide as a prebiotic activation agent for stereo-and sequence-selective, amyloid-templated peptide elongation
R Bomba, SK Rout, M Bütikofer, W Kwiatkowski, R Riek, J Greenwald
Origins of Life and Evolution of Biospheres 49, 213-224, 2019
62019
Rapid Protein–Ligand Affinity Determination by Photoinduced Hyperpolarized NMR
M Bütikofer, GR Stadler, H Kadavath, R Cadalbert, F Torres, R Riek
Journal of the American Chemical Society, 2024
22024
Ligand-target interaction analysis by photochemically induced dynamic nuclear polarization (photo-cidnp) enhanced nmr spectroscopy
F Torres, RP Riek, M Butikofer
US Patent App. 18/294,558, 2024
2024
Rescaling NMR for a Larger Deployment in Drug Discovery: Hyperpolarization and Benchtop NMR as Potential Game‐Changers
M Bütikofer, GR Stadler, F Torres
Chemistry‐Methods 4 (10), e202400009, 2024
2024
Light-coupled cryogenic probes to detect low-micromolar samples and allow for an automated NMR platform
W Wüster, P Gebbers, A Renn, M Bütikofer, S Rüdiger, RP Riek, F Torres
Magnetic Resonance 5 (1), 61-67, 2024
2024
Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies
N Altincekic, N Jores, F Löhr, C Richter, C Ehrhardt, MJJ Blommers, ...
ACS Chemical Biology 19 (2), 563-574, 2024
2024
From Screening to Structure: NMR-based Drug Discovery with Hyperpolarization and Isotope-free Structure Determination
M Bütikofer
ETH Zurich, 2024
2024
Short Lecture “Natural products against SARS-CoV-2 or how to catch a butterfly?”
A Wasilewicz, B Kirchweger, D Bojkova, MJ Abi Saad, J Langeder, ...
Planta Medica 88 (15), SL-RDF-01, 2022
2022
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