Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine K Cadwell, KK Patel, NS Maloney, TC Liu, ACY Ng, CE Storer, RD Head, ... Cell 141 (7), 1135-1145, 2010 | 1017 | 2010 |
SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function ES Winkler, AL Bailey, NM Kafai, S Nair, BT McCune, J Yu, JM Fox, ... Nature immunology 21 (11), 1327-1335, 2020 | 926 | 2020 |
Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo M Yadav, C Louvet, D Davini, JM Gardner, M Martinez-Llordella, ... Journal of Experimental Medicine 209 (10), 1713-1722, 2012 | 834 | 2012 |
Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550) K Ghoreschi, MI Jesson, X Li, JL Lee, S Ghosh, JW Alsup, JD Warner, ... The Journal of Immunology 186 (7), 4234-4243, 2011 | 725 | 2011 |
Effects of microbiota-directed foods in gnotobiotic animals and undernourished children JL Gehrig, S Venkatesh, HW Chang, MC Hibberd, VL Kung, J Cheng, ... Science 365 (6449), eaau4732, 2019 | 385 | 2019 |
Synechococcus elongatus UTEX 2973, a fast growing cyanobacterial chassis for biosynthesis using light and CO2 J Yu, M Liberton, PF Cliften, RD Head, JM Jacobs, RD Smith, ... Scientific reports 5 (1), 8132, 2015 | 383 | 2015 |
VALIDATE: A new method for the receptor-based prediction of binding affinities of novel ligands RD Head, ML Smythe, TI Oprea, CL Waller, SM Green, GR Marshall Journal of the American Chemical society 118 (16), 3959-3969, 1996 | 370 | 1996 |
Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection ES Winkler, P Gilchuk, J Yu, AL Bailey, RE Chen, Z Chong, SJ Zost, ... Cell 184 (7), 1804-1820. e16, 2021 | 348 | 2021 |
Autophagy proteins control goblet cell function by potentiating reactive oxygen species production KK Patel, H Miyoshi, WL Beatty, RD Head, NP Malvin, K Cadwell, ... The EMBO journal 32 (24), 3130-3144, 2013 | 284 | 2013 |
Rapid and extraction-free detection of SARS-CoV-2 from saliva by colorimetric reverse-transcription loop-mediated isothermal amplification MA Lalli, JS Langmade, X Chen, CC Fronick, CS Sawyer, LC Burcea, ... Clinical chemistry 67 (2), 415-424, 2021 | 216 | 2021 |
Validation of a next-generation sequencing assay for clinical molecular oncology CE Cottrell, H Al-Kateb, AJ Bredemeyer, EJ Duncavage, DH Spencer, ... The Journal of molecular diagnostics 16 (1), 89-105, 2014 | 201 | 2014 |
Tumor–stroma IL1β-IRAK4 feedforward circuitry drives tumor fibrosis, chemoresistance, and poor prognosis in pancreatic cancer D Zhang, L Li, H Jiang, Q Li, A Wang-Gillam, J Yu, R Head, J Liu, ... Cancer research 78 (7), 1700-1712, 2018 | 186 | 2018 |
JAK inhibition with tofacitinib suppresses arthritic joint structural damage through decreased RANKL production TP LaBranche, MI Jesson, ZA Radi, CE Storer, JA Guzova, SL Bonar, ... Arthritis & Rheumatism 64 (11), 3531-3542, 2012 | 162 | 2012 |
Paneth cell defects in Crohn’s disease patients promote dysbiosis TC Liu, B Gurram, MT Baldridge, R Head, V Lam, C Luo, Y Cao, ... JCI insight 1 (8), 2016 | 135 | 2016 |
Transcriptional profiling and pathway analysis of monosodium iodoacetate-induced experimental osteoarthritis in rats: relevance to human disease RA Barve, JC Minnerly, DJ Weiss, DM Meyer, DJ Aguiar, PM Sullivan, ... Osteoarthritis and Cartilage 15 (10), 1190-1198, 2007 | 113 | 2007 |
Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation TC Liu, JT Kern, U Jain, NM Sonnek, S Xiong, KF Simpson, ... Cell host & microbe 29 (6), 988-1001. e6, 2021 | 112 | 2021 |
URP1: a member of a novel family of PH and FERM domain-containing membrane-associated proteins is significantly over-expressed in lung and colon carcinomas EJ Weinstein, M Bourner, R Head, H Zakeri, C Bauer, R Mazzarella Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1637 (3), 207-216, 2003 | 99 | 2003 |
Abnormal small intestinal epithelial microvilli in patients with Crohn's disease KL VanDussen, A Stojmirović, K Li, TC Liu, PK Kimes, BD Muegge, ... Gastroenterology 155 (3), 815-828, 2018 | 88 | 2018 |
VCC-1, a novel chemokine, promotes tumor growth EJ Weinstein, R Head, DW Griggs, D Sun, RJ Evans, ML Swearingen, ... Biochemical and biophysical research communications 350 (1), 74-81, 2006 | 86 | 2006 |
Interaction between smoking and ATG16L1T300A triggers Paneth cell defects in Crohn’s disease TC Liu, JT Kern, KL VanDussen, S Xiong, GE Kaiko, CB Wilen, ... The Journal of clinical investigation 128 (11), 5110-5122, 2018 | 82 | 2018 |