Role of the Drosophila patched gene in positional signalling PW Ingham, AM Taylor, Y Nakano Nature 353 (6340), 184-187, 1991 | 577 | 1991 |
A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched Y Nakano, I Guerrero, A Hidalgo, A Taylor, JRS Whittle, PW Ingham Nature 341 (6242), 508-513, 1989 | 429 | 1989 |
New susceptibility loci associated with kidney disease in type 1 diabetes N Sandholm, RM Salem, AJ McKnight, EP Brennan, C Forsblom, ... Public Library of Science 8 (9), e1002921, 2012 | 278 | 2012 |
Genetic analysis of hedgehog signalling in the Drosophila embryo AJ Forbes, Y Nakano, AM Taylor, PW Ingham Development 119 (Supplement), 115-124, 1993 | 263 | 1993 |
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers CF Houlihan, N Vora, T Byrne, D Lewer, G Kelly, J Heaney, S Gandhi, ... The Lancet 396 (10246), e6-e7, 2020 | 249 | 2020 |
Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation H Strutt, C Thomas, Y Nakano, D Stark, B Neave, AM Taylor, PW Ingham Current biology 11 (8), 608-613, 2001 | 243 | 2001 |
Unusual sensitivity of ataxia telangiectasia cells to bleomycin AMR Taylor, CM Rosney, JB Campbell Cancer research 39 (3), 1046-1050, 1979 | 197 | 1979 |
Ataxia telangiectasia mutated–deficient B-cell chronic lymphocytic leukemia occurs in pregerminal center cells and results in defective damage response and unrepaired … T Stankovic, GS Stewart, C Fegan, P Biggs, J Last, PJ Byrd, RD Keenan, ... Blood, The Journal of the American Society of Hematology 99 (1), 300-309, 2002 | 196 | 2002 |
Analysis of the ATM protein in wild-type and ataxia telangiectasia cells. ND Lakin, P Weber, T Stankovic, ST Rottinghaus, AM Taylor, SP Jackson Oncogene 13 (12), 2707-2716, 1996 | 195 | 1996 |
Patched represses the Hedgehog signalling pathway by promoting modification of the Smoothened protein PW Ingham, S Nystedt, Y Nakano, W Brown, D Stark, M Van den Heuvel, ... Current Biology 10 (20), 1315-1318, 2000 | 184 | 2000 |
Contrasting distributions of patched and hedgehog proteins in the Drosophila embryo AM Taylor, Y Nakano, J Mohler, PW Ingham Mechanisms of development 42 (1-2), 89-96, 1993 | 162 | 1993 |
Improved detection of cerebral hypoperfusion with internal carotid balloon test occlusion and 99mTc-HMPAO cerebral perfusion SPECT imaging. SB Peterman, A Taylor, JC Hoffman American journal of neuroradiology 12 (6), 1035-1041, 1991 | 144 | 1991 |
Association testing of previously reported variants in a large case-control meta-analysis of diabetic nephropathy WW Williams, RM Salem, AJ McKnight, N Sandholm, C Forsblom, ... Diabetes 61 (8), 2187-2194, 2012 | 107 | 2012 |
Secretion of the amino-terminal fragment of the hedgehog protein is necessary and sufficient for hedgehog signalling in Drosophila MJ Fietz, A Jacinto, AM Taylor, C Alexandre, PW Ingham Current Biology 5 (6), 643-650, 1995 | 98 | 1995 |
A family showing no evidence of linkage between the ataxia telangiectasia gene and chromosome 11q22-23. D Hernandez, CM McConville, M Stacey, CG Woods, MM Brown, P Shutt, ... Journal of medical genetics 30 (2), 135-140, 1993 | 97 | 1993 |
Variant forms of ataxia telangiectasia. AM Taylor, E Flude, B Laher, M Stacey, E McKay, J Watt, SH Green, ... Journal of medical genetics 24 (11), 669-677, 1987 | 95 | 1987 |
Thiamine deficiency and malaria in adults from southeast Asia S Krishna, AM Taylor, W Supanaranond, S Pukrittayakamee, F Ter Kuile, ... The Lancet 353 (9152), 546-549, 1999 | 91 | 1999 |
Ataxia telangiectasia genes and predisposition to leukaemia, lymphoma and breast cancer. AM Taylor British journal of cancer 66 (1), 5, 1992 | 89 | 1992 |
Ataxia-telangiectasia: immunodeficiency and survival NJ Van Os, AFM Jansen, M Van Deuren, A Haraldsson, NT Van Driel, ... Clinical Immunology 178, 45-55, 2017 | 88 | 2017 |
The C allele of ATM rs11212617 does not associate with metformin response in the Diabetes Prevention Program JC Florez, KA Jablonski, A Taylor, K Mather, E Horton, NH White, ... Diabetes care 35 (9), 1864-1867, 2012 | 76 | 2012 |