Immune or genetic-mediated disruption of CASPR2 causes pain hypersensitivity due to enhanced primary afferent excitability JM Dawes, GA Weir, SJ Middleton, R Patel, KI Chisholm, P Pettingill, ... Neuron 97 (4), 806-822. e10, 2018 | 155 | 2018 |
Studying human nociceptors: from fundamentals to clinic SJ Middleton, AM Barry, M Comini, Y Li, PR Ray, S Shiers, ... Brain 144 (5), 1312-1335, 2021 | 111 | 2021 |
Using an engineered glutamate-gated chloride channel to silence sensory neurons and treat neuropathic pain at the source GA Weir, SJ Middleton, AJ Clark, T Daniel, N Khovanov, SB McMahon, ... Brain 140 (10), 2570-2585, 2017 | 66 | 2017 |
Nav1. 7 is required for normal C-low threshold mechanoreceptor function in humans and mice SJ Middleton, I Perini, AC Themistocleous, GA Weir, K McCann, AM Barry, ... Brain, 2021 | 23 | 2021 |
Congenital deafness is associated with specific somatosensory deficits in adolescents R Moshourab, V Bégay, C Wetzel, J Walcher, S Middleton, M Gross, ... Scientific Reports 7 (1), 4251, 2017 | 17 | 2017 |
Sodium-calcium exchanger-3 regulates pain “wind-up”: From human psychophysics to spinal mechanisms T Trendafilova, K Adhikari, AB Schmid, R Patel, E Polgár, KI Chisholm, ... Neuron 110 (16), 2571-2587. e13, 2022 | 13 | 2022 |
The structure of sensory afferent compartments in health and disease SJ Middleton, J Perez‐Sanchez, JM Dawes Journal of Anatomy 241 (5), 1186-1210, 2022 | 12 | 2022 |
A humanized chemogenetic system inhibits murine pain-related behavior and hyperactivity in human sensory neurons J Perez-Sanchez, SJ Middleton, LA Pattison, H Hilton, ... Science translational medicine 15 (716), eadh3839, 2023 | 5 | 2023 |
Long-term tactile hypersensitivity after nerve crush injury in mice is characterized by the persistence of intact sensory axons HW Kim, SW Shim, AM Zhao, D Roh, HM Han, SJ Middleton, W Kim, ... Pain, 10.1097, 2023 | 2 | 2023 |
Inhibition of sensory neuron driven acute, inflammatory, and neuropathic pain using a humanised chemogenetic system J Perez-Sanchez, SJ Middleton, LA Pattison, H Hilton, MA Awadelkareem, ... bioRxiv, 2023.03. 21.533690, 2023 | 1 | 2023 |
Characterising the stimulus-response function of mouse C-low threshold mechanoreceptors to mechanical stimuli in vivo E Semizoglou, L Lo-Re, SJ Middleton, J Perez Sanchez, T Tufarelli, ... bioRxiv, 2024.03. 18.585483, 2024 | | 2024 |
GluCl. CreON enables selective inhibition of molecularly defined pain circuits SJ Middleton, H Hu, J Perez-Sanchez, S Zuberi, JMG Williams, GA Weir, ... Pain, 10.1097, 2023 | | 2023 |