| Transition‐Metal‐Mediated and‐Catalyzed C− F Bond Activation by Fluorine Elimination T Fujita, K Fuchibe, J Ichikawa Angewandte Chemie International Edition 58 (2), 390-402, 2019 | 399 | 2019 |
| Efficient Helicene Synthesis: Friedel–Crafts‐type Cyclization of 1, 1‐Difluoro‐1‐alkenes J Ichikawa, M Yokota, T Kudo, S Umezaki Angewandte Chemie International Edition 47 (26), 4870-4873, 2008 | 181 | 2008 |
| Nickel-Catalyzed Allylic C(sp3)–F Bond Activation of Trifluoromethyl Groups via β-Fluorine Elimination: Synthesis of Difluoro-1,4-dienes T Ichitsuka, T Fujita, J Ichikawa ACS Catalysis 5 (10), 5947-5950, 2015 | 178 | 2015 |
| Substitution of Two Fluorine Atoms in a Trifluoromethyl Group: Regioselective Synthesis of 3‐Fluoropyrazoles K Fuchibe, M Takahashi, J Ichikawa Angewandte Chemie 48 (124), 12225-12228, 2012 | 164 | 2012 |
| Lewis Acid Promoted Single C–F Bond Activation of the CF3 Group: SN1′‐Type 3,3‐Difluoroallylation of Arenes with 2‐Trifluoromethyl‐1‐alkenes K Fuchibe, H Hatta, K Oh, R Oki, J Ichikawa Angewandte Chemie International Edition 56 (21), 5890-5893, 2017 | 160 | 2017 |
| Double C F Bond Activation through β‐Fluorine Elimination: Nickel‐Mediated [3+ 2] Cycloaddition of 2‐Trifluoromethyl‐1‐alkenes with Alkynes T Ichitsuka, T Fujita, T Arita, J Ichikawa Angewandte Chemie International Edition 53 (29), 7564-7568, 2014 | 153 | 2014 |
| gem-Difluoroolefin synthesis: general methods via thermostable difluorovinylmetals starting from 2, 2, 2-trifluoroethanol derivatives J Ichikawa Journal of Fluorine Chemistry 105 (2), 257-263, 2000 | 110 | 2000 |
| 1-Trifluoromethylvinylsilane as a CF2C-−CH2+ Synthon: Synthesis of Functionalized 1,1-Difluoro-1-alkenes via Isolable 2,2-Difluorovinylsilanes J Ichikawa, H Fukui, Y Ishibashi The Journal of Organic Chemistry 68 (20), 7800-7805, 2003 | 109 | 2003 |
| Ring-Fluorinated Isoquinoline and Quinoline Synthesis: Intramolecular Cyclization of o-Cyano- and o-Isocyano-β,β-difluorostyrenes J Ichikawa, Y Wada, H Miyazaki, T Mori, H Kuroki Organic Letters 5 (9), 1455-1458, 2003 | 108 | 2003 |
| Fluorine-directed nazarov cyclizations: a controlled synthesis of cross-conjugated 2-cyclopenten-1-ones J Ichikawa, S Miyazaki, M Fujiwara, T Minami The Journal Of Organic Chemistry 60 (8), 2320-2321, 1995 | 105 | 1995 |
| Activation of 1, 1-Difluoro-1-alkenes with a transition-metal complex: palladium (II)-Catalyzed friedel–crafts-type cyclization of 4, 4-(difluorohomoallyl) arenes M Yokota, D Fujita, J Ichikawa Organic Letters 9 (22), 4639-4642, 2007 | 92 | 2007 |
| Domino synthesis of fluorine-substituted polycyclic aromatic hydrocarbons: 1, 1-difluoroallenes as synthetic platforms. K Fuchibe, Y Mayumi, N Zhao, S Watanabe, M Yokota, J Ichikawa Angewandte Chemie 125 (30), 2013 | 89 | 2013 |
| The nucleophilic 5-endo-trig cyclization of 1, 1-difluoro-1-alkenes: ring-fluorinated hetero-and carbocycle synthesis and remarkable effect of the vinylic fluorines on the … J Ichikawa, Y Wada, M Fujiwara, K Sakoda Synthesis 2002 (13), 1917-1936, 2002 | 83 | 2002 |
| Domino Friedel–Crafts‐Type Cyclizations of Difluoroalkenes Promoted by the α‐Cation‐Stabilizing Effect of Fluorine: An Efficient Method for Synthesizing Angular PAHs K Fuchibe, H Jyono, M Fujiwara, T Kudo, M Yokota, J Ichikawa Chemistry–A European Journal 17 (43), 12175-12185, 2011 | 79 | 2011 |
| Synthesis and synthetic utilization of α-functionalized vinylphosphonates bearing β-oxy or β-thio substituents R Kouno, T Okauchi, M Nakamura, J Ichikawa, T Minami The Journal of Organic Chemistry 63 (18), 6239-6246, 1998 | 74 | 1998 |
| Domino C–F Bond Activation of the CF3 Group: Synthesis of Fluorinated Dibenzo[a,c][7]annulenes from 2-(Trifluoromethyl)-1-alkenes and 2,2′-Diceriobiaryls T Fujita, M Takazawa, K Sugiyama, N Suzuki, J Ichikawa Organic letters 19 (3), 588-591, 2017 | 71 | 2017 |
| Heck-type 5-endo-trig cyclizations promoted by vinylic fluorines: Ring-fluorinated indene and 3H-pyrrole syntheses from 1, 1-difluoro-1-alkenes J Ichikawa, K Sakoda, J Mihara, N Ito Journal of fluorine chemistry 127 (4-5), 489-504, 2006 | 67 | 2006 |
| 5-endo Heck-type cyclization of 2-(trifluoromethyl) allyl ketone oximes: synthesis of 4-difluoromethylene-substituted 1-pyrrolines J Ichikawa, R Nadano, N Ito Chemical communications, 4425-4427, 2006 | 67 | 2006 |
| A one-pot synthesis of 2, 2-difluorovinyl carbonyl compounds from 2, 2, 2,-trifluoroethyl p-toluenesulfonate via 2, 2-difluorovinylboranes J Ichikawa, S Hamada, T Sonoda, H Kobayashi Tetrahedron letters 33 (3), 337-340, 1992 | 67 | 1992 |
| Vinylic C F bond activation with low-valent zirconocene: the generation and cross-coupling reactions of 1-fluorovinylzirconocene M Fujiwara, J Ichikawa, T Okauchi, T Minami Tetrahedron letters 40 (40), 7261-7265, 1999 | 66 | 1999 |
