Pyridine-derived triflating reagents: An improved preparation of vinyl triflates from metallo enolates. DL Comins, A Dehghani Tetrahedron letters 33 (42), 6299-6302, 1992 | 660 | 1992 |
Asymmetric synthesis of 2-alkyl (aryl)-2, 3-dihydro-4-pyridones by addition of Grignard reagents to chiral 1-acyl-4-methoxypyridinium salts DL Comins, SP Joseph, RR Goehring Journal of the American Chemical Society 116 (11), 4719-4728, 1994 | 288 | 1994 |
Regioselective addition of Grignard reagents to 1-acylpyridinium salts. A convenient method for the synthesis of 4-alkyl (aryl) pyridines DL Comins, AH Abdullah The Journal of Organic Chemistry 47 (22), 4315-4319, 1982 | 260 | 1982 |
Ortho metalation directed by. alpha.-amino alkoxides DL Comins, JD Brown The Journal of organic chemistry 49 (6), 1078-1083, 1984 | 246 | 1984 |
Asymmetric synthesis of 3-substituted isoindolinones: Application to the total synthesis of (+)-lennoxamine DL Comins, S Schilling, Y Zhang Organic Letters 7 (1), 95-98, 2005 | 186 | 2005 |
A 10-step, asymmetric synthesis of (S)-camptothecin DL Comins, MF Baevsky, H Hong Journal of the american Chemical Society 114 (27), 10971-10972, 1992 | 185 | 1992 |
A Practical Six-Step Synthesis of (S)-Camptothecin DL Comins, JM Nolan Organic letters 3 (26), 4255-4257, 2001 | 161 | 2001 |
A highly stereocontrolled, four-step synthesis of (.+-.)-lasubine II JD Brown, MA Foley, DL Comins Journal of the American Chemical Society 110 (22), 7445-7447, 1988 | 156 | 1988 |
Lithiation of heterocycles directed by. alpha.-amino alkoxides DL Comins, MO Killpack The Journal of Organic Chemistry 52 (1), 104-109, 1987 | 147 | 1987 |
Regioselective substitution in aromatic six-membered nitrogen heterocycles DL Comins, S O'Connor Advances in heterocyclic chemistry 44, 199-267, 1988 | 142 | 1988 |
Enantiopure N-Acyldihydropyridones as Synthetic Intermediates: Asymmetric Syntheses of Indolizidine Alkaloids (−)-205A, (−)-207A, and (−)-235B DL Comins, DH LaMunyon, X Chen The Journal of Organic Chemistry 62 (23), 8182-8187, 1997 | 130 | 1997 |
A Six-Step Synthesis of (.+-.)-Camptothecin DL Comins, H Hong, JK Saha, G Jianhua The Journal of Organic Chemistry 59 (18), 5120-5121, 1994 | 128 | 1994 |
N-vs. O-Alkylation in the mitsunobu reaction of 2-pyridone DL Comins, G Jianhua Tetrahedron letters 35 (18), 2819-2822, 1994 | 125 | 1994 |
Lithiation of methoxypyridines directed by. alpha.-amino alkoxides DL Comins, MO Killpack The Journal of Organic Chemistry 55 (1), 69-73, 1990 | 123 | 1990 |
Ortho lithiation of 2-, 3-, and 4-methoxypyridines DL Comins, DH LaMunyon Tetrahedron letters 29 (7), 773-776, 1988 | 121 | 1988 |
Synthesis and reactions of. alpha.-(trifluoromethanesulfonyloxy) enecarbamates prepared from N-acyllactams CJ Foti, DL Comins The Journal of Organic Chemistry 60 (9), 2656-2657, 1995 | 120 | 1995 |
TetrahedronLett. 1986, 27, 4549. An auxiliary-mediated process has also been developed to provide these substrates in optically pure form. See: Comins, DL; Goehring, R.; Joseph … DL Comins, JD Brown J. Org. Chem 55, 2574, 1990 | 117 | 1990 |
Asymmetric synthesis of camptothecin alkaloids: a nine-step synthesis of (S)-camptothecin DL Comins, H Hong, G Jianhua Tetrahedron letters 35 (30), 5331-5334, 1994 | 115 | 1994 |
Enantiopure N-Acyldihydropyridones as Synthetic Intermediates: Asymmetric Synthesis of (−)-Septicine and (−)-Tylophorine DL Comins, X Chen, LA Morgan The Journal of Organic Chemistry 62 (21), 7435-7438, 1997 | 113 | 1997 |
Enantiopure 2, 3-dihydro-4-pyridones as synthetic intermediates. Asymmetric syntheses of the quinolizidine alkaloids,(+)-myrtine,(-)-lasubine I, and (+)-subcosine I DL Comins, DH LaMunyon The Journal of Organic Chemistry 57 (22), 5807-5809, 1992 | 109 | 1992 |