Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden ZR Chalmers, CF Connelly, D Fabrizio, L Gay, SM Ali, R Ennis, A Schrock, ... Genome medicine 9, 1-14, 2017 | 3044 | 2017 |
Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas Cancer Genome Atlas Research Network New England Journal of Medicine 372 (26), 2481-2498, 2015 | 2969 | 2015 |
Genomic classification of cutaneous melanoma R Akbani, KC Akdemir, B áArman Aksoy, M Albert, A Ally, SB Amin, ... Cell 161 (7), 1681-1696, 2015 | 2758 | 2015 |
Integrated genomic characterization of papillary thyroid carcinoma N Agrawal, R Akbani, BA Aksoy, A Ally, H Arachchi, SL Asa, JT Auman, ... Cell 159 (3), 676-690, 2014 | 2599 | 2014 |
Next-generation characterization of the cancer cell line encyclopedia M Ghandi, FW Huang, J Jané-Valbuena, GV Kryukov, CC Lo, ... Nature 569 (7757), 503-508, 2019 | 2568 | 2019 |
Highly recurrent TERT promoter mutations in human melanoma FW Huang, E Hodis, MJ Xu, GV Kryukov, L Chin, LA Garraway Science 339 (6122), 957-959, 2013 | 2146 | 2013 |
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression JL Babitt, FW Huang, DM Wrighting, Y Xia, Y Sidis, TA Samad, ... Nature genetics 38 (5), 531-539, 2006 | 1326 | 2006 |
The long tail of oncogenic drivers in prostate cancer J Armenia, SAM Wankowicz, D Liu, J Gao, R Kundra, E Reznik, ... Nature genetics 50 (5), 645-651, 2018 | 755 | 2018 |
Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance JL Babitt, FW Huang, Y Xia, Y Sidis, NC Andrews, HY Lin The Journal of clinical investigation 117 (7), 1933-1939, 2007 | 632 | 2007 |
Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine EM Van Allen, N Wagle, P Stojanov, DL Perrin, K Cibulskis, S Marlow, ... Nature medicine 20 (6), 682-688, 2014 | 570 | 2014 |
The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans The Tabula Sapiens Consortium*, RC Jones, J Karkanias, MA Krasnow, ... Science 376 (6594), eabl4896, 2022 | 540 | 2022 |
A mouse model of juvenile hemochromatosis FW Huang, JL Pinkus, GS Pinkus, MD Fleming, NC Andrews The Journal of clinical investigation 115 (8), 2187-2191, 2005 | 447 | 2005 |
The DNA methylation landscape of advanced prostate cancer SG Zhao, WS Chen, H Li, A Foye, M Zhang, M Sjöström, R Aggarwal, ... Nature genetics 52 (8), 778-789, 2020 | 250 | 2020 |
Distinct classes of complex structural variation uncovered across thousands of cancer genome graphs K Hadi, X Yao, JM Behr, A Deshpande, C Xanthopoulakis, H Tian, ... Cell 183 (1), 197-210. e32, 2020 | 179 | 2020 |
Expression of ACE2, the SARS-CoV-2 receptor, and TMPRSS2 in prostate epithelial cells H Song, B Seddighzadeh, MR Cooperberg, FW Huang European urology 78 (2), 296, 2020 | 155 | 2020 |
Prostate cancer–specific mortality across Gleason scores in black vs nonblack men BA Mahal, RA Berman, ME Taplin, FW Huang Jama 320 (23), 2479-2481, 2018 | 144 | 2018 |
Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states H Song, HNW Weinstein, P Allegakoen, MH Wadsworth, J Xie, H Yang, ... Nature communications 13 (1), 141, 2022 | 128 | 2022 |
Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations FW Huang, JM Mosquera, A Garofalo, C Oh, M Baco, A Amin-Mansour, ... Cancer discovery 7 (9), 973-983, 2017 | 122 | 2017 |
TERT promoter mutations and monoallelic activation of TERT in cancer FW Huang, CM Bielski, ML Rinne, WC Hahn, WR Sellers, F Stegmeier, ... Oncogenesis 4 (12), e176-e176, 2015 | 94 | 2015 |
Rapid intraoperative molecular characterization of glioma GM Shankar, JM Francis, ML Rinne, SH Ramkissoon, FW Huang, ... JAMA oncology 1 (5), 662-667, 2015 | 88 | 2015 |