C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis SP Allen, B Hall, R Woof, L Francis, N Gatto, AC Shaw, M Myszczynska, ... Brain 142 (12), 3771-3790, 2019 | 77 | 2019 |
Directly converted astrocytes retain the ageing features of the donor fibroblasts and elucidate the astrocytic contribution to human CNS health and disease N Gatto, C Dos Santos Souza, AC Shaw, SM Bell, MA Myszczynska, ... Aging Cell 20 (1), e13281, 2021 | 45 | 2021 |
RNS60 exerts therapeutic effects in the SOD1 ALS mouse model through protective glia and peripheral nerve rescue A Vallarola, F Sironi, M Tortarolo, N Gatto, R De Gioia, L Pasetto, ... Journal of neuroinflammation 15, 1-22, 2018 | 40 | 2018 |
Adipose-derived stem cells protect motor neurons and reduce glial activation in both in vitro and in vivo models of ALS Y Ciervo, N Gatto, C Allen, A Grierson, L Ferraiuolo, RJ Mead, PJ Shaw Molecular Therapy-Methods & Clinical Development 21, 413-433, 2021 | 16 | 2021 |
Age-related changes affect human astrocyte function and have important implications for the function of SOD1 and its role in amyotrophic lateral sclerosis (ALS) N Gatto University of Sheffield, 2020 | | 2020 |
Antioxidant drugs reveal the potential for patient stratification in Motor Neurone C Allen, M Myszczynska, M Stopford, N Gatto, H Mortiboys, G Hautbergue, ... | | |