IL-22 is required for Th17 cell–mediated pathology in a mouse model of psoriasis-like skin inflammation HL Ma, S Liang, J Li, L Napierata, T Brown, S Benoit, M Senices, D Gill, ... The Journal of clinical investigation 118 (2), 597-607, 2008 | 760 | 2008 |
Review on EGFR inhibitors: critical updates D Singh, BK Attri, RK Gill, J Bariwal Mini reviews in medicinal chemistry 16 (14), 1134-1166, 2016 | 204 | 2016 |
Immunotherapy reduces vascular amyloid-β in PDAPP mice S Schroeter, K Khan, R Barbour, MT Doan, M Chen, T Guido, D Gill, ... Journal of Neuroscience 28 (27), 6787-6793, 2008 | 153 | 2008 |
Biopharmaceutical drug discovery using novel protein scaffolds DS Gill, NK Damle Current opinion in biotechnology 17 (6), 653-658, 2006 | 147 | 2006 |
Affinity maturation of a humanized rat antibody for anti-RAGE therapy: comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the … WJ Finlay, O Cunningham, MA Lambert, A Darmanin-Sheehan, X Liu, ... Journal of molecular biology 388 (3), 541-558, 2009 | 115 | 2009 |
Amyloid-beta immunotherapy for the prevention and treatment of Alzheimer disease: lessons from mice, monkeys, and humans CA Lemere, M Maier, L Jiang, Y Peng, TJ Seabrook Rejuvenation research 9 (1), 77-84, 2006 | 113 | 2006 |
Isothermal titration calorimetric study of the association of hen egg lysozyme and the anti-lysozyme antibody HyHEL-5 KA Hibbits, DS Gill, RC Willson Biochemistry 33 (12), 3584-3590, 1994 | 113 | 1994 |
Fundamental characteristics of the immunoglobulin VH repertoire of chickens in comparison with those of humans, mice, and camelids L Wu, K Oficjalska, M Lambert, BJ Fennell, A Darmanin-Sheehan, ... The Journal of immunology 188 (1), 322-333, 2012 | 110 | 2012 |
Improving the pharmacokinetic properties of biologics by fusion to an anti-HSA shark VNAR domain MR Müller, K Saunders, C Grace, M Jin, N Piche-Nicholas, J Steven, ... MAbs 4 (6), 673-685, 2012 | 107 | 2012 |
Atypical antigen recognition mode of a shark immunoglobulin new antigen receptor (IgNAR) variable domain characterized by humanization and structural analysis OV Kovalenko, A Olland, N Piché-Nicholas, A Godbole, D King, ... Journal of Biological Chemistry 288 (24), 17408-17419, 2013 | 105 | 2013 |
Protein adsorption kinetics drastically altered by repositioning a single charge JJ Ramsden, DJ Roush, DS Gill, R Kurrat, RC Willson Journal of the American Chemical Society 117 (33), 8511-8516, 1995 | 98 | 1995 |
Coupling of aggregation and immunogenicity in biotherapeutics: T-and B-cell immune epitopes may contain aggregation-prone regions S Kumar, SK Singh, X Wang, B Rup, D Gill Pharmaceutical research 28, 949-961, 2011 | 90 | 2011 |
IL-13 binding agents L Tchistiakova, MT Kasaian, DD Donaldson, XY Tan, D Gill, MX Jin, ... US Patent 7,501,121, 2009 | 87 | 2009 |
Novel agonist monoclonal antibodies activate TrkB receptors and demonstrate potent neurotrophic activities MD Qian, J Zhang, XY Tan, A Wood, D Gill, S Cho Journal of Neuroscience 26 (37), 9394-9403, 2006 | 82 | 2006 |
Immunotherapy Regimes Dependent On APOE Status R Black, L Ekman, I Lieberburg, M Grundman, J Callaway, KM Gregg, ... US Patent App. 12/253,929, 2009 | 81 | 2009 |
Antibody capture of soluble Aβ does not reduce cortical Aβ amyloidosis in the PDAPP mouse P Seubert, R Barbour, K Khan, R Motter, P Tang, D Kholodenko, K Kling, ... Neurodegenerative Diseases 5 (2), 65-71, 2008 | 79 | 2008 |
Electrostatic potentials and electrostatic interaction energies of rat cytochrome b5 and a simulated anion-exchange adsorbent surface DJ Roush, DS Gill, RC Willson Biophysical journal 66 (5), 1290-1300, 1994 | 79 | 1994 |
Children’s experiences of epilepsy: a systematic review of qualitative studies L Chong, NJ Jamieson, D Gill, D Singh-Grewal, JC Craig, A Ju, ... Pediatrics 138 (3), 2016 | 75 | 2016 |
High‐throughput measurement, correlation analysis, and machine‐learning predictions for pH and thermal stabilities of Pfizer‐generated antibodies AC King, M Woods, W Liu, Z Lu, D Gill, MRH Krebs Protein Science 20 (9), 1546-1557, 2011 | 71 | 2011 |
Shark novel antigen receptors—the next generation of biologic therapeutics? C Barelle, DS Gill, K Charlton Pharmaceutical Biotechnology, 49-62, 2009 | 71 | 2009 |