CRISPR screens uncover genes that regulate target cell sensitivity to the morphogen sonic hedgehog GV Pusapati, JH Kong, BB Patel, A Krishnan, A Sagner, M Kinnebrew, ... Developmental cell 44 (1), 113-129. e8, 2018 | 139 | 2018 |
Cholesterol accessibility at the ciliary membrane controls hedgehog signaling M Kinnebrew, EJ Iverson, BB Patel, GV Pusapati, JH Kong, KA Johnson, ... Elife 8, e50051, 2019 | 115 | 2019 |
Determining the oligomeric structure of proteorhodopsin by Gd3+-based pulsed dipolar spectroscopy of multiple distances DT Edwards, T Huber, S Hussain, KM Stone, M Kinnebrew, I Kaminker, ... Structure 22 (11), 1677-1686, 2014 | 96 | 2014 |
Protein structural and surface water rearrangement constitute major events in the earliest aggregation stages of tau A Pavlova, CY Cheng, M Kinnebrew, J Lew, FW Dahlquist, S Han Proceedings of the National Academy of Sciences 113 (2), E127-E136, 2016 | 89 | 2016 |
Structural insight into proteorhodopsin oligomers KM Stone, J Voska, M Kinnebrew, A Pavlova, MJN Junk, S Han Biophysical journal 104 (2), 472-481, 2013 | 68 | 2013 |
The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism AF Rudolf, M Kinnebrew, C Kowatsch, TB Ansell, K El Omari, B Bishop, ... Nature chemical biology 15 (10), 975-982, 2019 | 62 | 2019 |
Structures of vertebrate Patched and Smoothened reveal intimate links between cholesterol and Hedgehog signalling C Kowatsch, RE Woolley, M Kinnebrew, R Rohatgi, C Siebold Current opinion in structural biology 57, 204-214, 2019 | 58 | 2019 |
Functional consequences of the oligomeric assembly of proteorhodopsin S Hussain, M Kinnebrew, NS Schonenbach, E Aye, S Han Journal of molecular biology 427 (6), 1278-1290, 2015 | 51 | 2015 |
Human–chimpanzee fused cells reveal cis-regulatory divergence underlying skeletal evolution D Gokhman, RM Agoglia, M Kinnebrew, W Gordon, D Sun, VK Bajpai, ... Nature genetics 53 (4), 467-476, 2021 | 41 | 2021 |
Patched 1 reduces the accessibility of cholesterol in the outer leaflet of membranes M Kinnebrew, G Luchetti, R Sircar, S Frigui, LV Viti, T Naito, F Beckert, ... Elife 10, e70504, 2021 | 38 | 2021 |
Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain M Kinnebrew, RE Woolley, TB Ansell, EFX Byrne, S Frigui, G Luchetti, ... Science Advances 8 (22), eabm5563, 2022 | 21 | 2022 |
The energetics and ion coupling of cholesterol transport through Patched1 TB Ansell, RA Corey, LV Viti, M Kinnebrew, R Rohatgi, C Siebold, ... Science Advances 9 (34), eadh1609, 2023 | 3 | 2023 |
Lipid membrane mimetics and oligomerization tune functional properties of proteorhodopsin CT Han, KDQ Nguyen, MW Berkow, S Hussain, A Kiani, M Kinnebrew, ... Biophysical Journal 122 (1), 168-179, 2023 | 3 | 2023 |
Direct ionic stress sensing and mitigation by the transcription factor NFAT5 CB Khandwala, P Sarkar, HB Schmidt, M Ma, M Kinnebrew, GV Pusapati, ... bioRxiv, 2023 | 1 | 2023 |
Measuring and Manipulating Membrane Cholesterol for the Study of Hedgehog Signaling M Kinnebrew, KA Johnson, A Radhakrishnan, R Rohatgi Hedgehog Signaling: Methods and Protocols, 73-87, 2022 | 1 | 2022 |
A cholesterol-binding bacterial toxin provides a strategy for identifying a specific Scap inhibitor that blocks lipid synthesis in animal cells S Xu, JC Smothers, D Rye, S Endapally, H Chen, S Li, G Liang, ... Proceedings of the National Academy of Sciences 121 (7), e2318024121, 2024 | | 2024 |
Suggested searches P Sacchi, SE Wright, P Neoptolemou, GI Lampronti, AK Rajagopalan, ... Perspective, 2024 | | 2024 |
Suggested searches B de Haas, N Brunette, A Goodson, J Dauparas, YY Sue, EC Yang, ... Perspective, 2023 | | 2023 |