| Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors W Yu, EJ Chory, AK Wernimont, W Tempel, A Scopton, A Federation, ... Nature communications 3 (1), 1288, 2012 | 305 | 2012 |
| Selective apoptosis-inducing activity of crinum-type Amaryllidaceae alkaloids J McNulty, JJ Nair, C Codina, J Bastida, S Pandey, J Gerasimoff, C Griffin Phytochemistry 68 (7), 1068-1074, 2007 | 171 | 2007 |
| Pancratistatin causes early activation of caspase-3 and the flipping of phosphatidyl serine followed by rapid apoptosis specifically in human lymphoma cells N Kekre, C Griffin, J McNulty, S Pandey Cancer chemotherapy and pharmacology 56, 29-38, 2005 | 144 | 2005 |
| Selective induction of apoptosis through activation of caspase-8 in human leukemia cells (Jurkat) by dandelion root extract P Ovadje, S Chatterjee, C Griffin, C Tran, C Hamm, S Pandey Journal of ethnopharmacology 133 (1), 86-91, 2011 | 141 | 2011 |
| Structure-activity studies on the lycorine pharmacophore: A potent inducer of apoptosis in human leukemia cells J McNulty, JJ Nair, J Bastida, S Pandey, C Griffin Phytochemistry 70 (7), 913-919, 2009 | 129 | 2009 |
| Potent targeting of the STAT3 protein in brain cancer stem cells: a promising route for treating glioblastoma S Haftchenary, HA Luchman, AO Jouk, AJ Veloso, BDG Page, XR Cheng, ... ACS medicinal chemistry letters 4 (11), 1102-1107, 2013 | 127 | 2013 |
| An allosteric inhibitor of protein arginine methyltransferase 3 A Siarheyeva, G Senisterra, A Allali-Hassani, A Dong, E Dobrovetsky, ... Structure 20 (8), 1425-1435, 2012 | 104 | 2012 |
| Pancratistatin selectively targets cancer cell mitochondria and reduces growth of human colon tumor xenografts C Griffin, A Karnik, J McNulty, S Pandey Molecular Cancer Therapeutics 10 (1), 57-68, 2011 | 89 | 2011 |
| Selective cytotoxicity of Pancratistatin-related natural Amaryllidaceae alkaloids: evaluation of the activity of two new compounds C Griffin, N Sharda, D Sood, J Nair, J McNulty, S Pandey Cancer Cell International 7, 1-7, 2007 | 84 | 2007 |
| Synergy of Pancratistatin and Tamoxifen on breast cancer cells in inducing apoptosis by targeting mitochondria P Siedlakowski, A McLachlan-Burgess, C Griffin, SS Tirumalai, J McNulty, ... Cancer biology & therapy 7 (3), 376-384, 2008 | 82 | 2008 |
| Chemoenzymatic synthesis of Amaryllidaceae constituents and biological evaluation of their C-1 analogues. The next generation synthesis of 7-deoxypancratistatin and trans … J Collins, U Rinner, M Moser, T Hudlicky, I Ghiviriga, AE Romero, ... The Journal of organic chemistry 75 (9), 3069-3084, 2010 | 75 | 2010 |
| Synthesis and Biological Evaluation of Fully Functionalized seco-Pancratistatin Analogues J McNulty, JJ Nair, C Griffin, S Pandey Journal of natural products 71 (3), 357-363, 2008 | 63 | 2008 |
| Pancratistatin induces apoptosis and autophagy in metastatic prostate cancer cells C Griffin, J McNULTY, S Pandey International journal of oncology 38 (6), 1549-1556, 2011 | 62 | 2011 |
| Pancratistatin induces apoptosis in clinical leukemia samples with minimal effect on non-cancerous peripheral blood mononuclear cells C Griffin, C Hamm, J McNulty, S Pandey Cancer cell international 10, 1-7, 2010 | 59 | 2010 |
| Structure activity studies on the crinane alkaloid apoptosis-inducing pharmacophore J McNulty, JJ Nair, J Bastida, S Pandey, C Griffin Natural Product Communications 4 (4), 1934578X0900400408, 2009 | 41 | 2009 |
| Design, synthesis, and characterization of 4-aminoquinazolines as potent inhibitors of the G protein-coupled receptor kinase 6 (GRK6) for the treatment of multiple myeloma DE Uehling, B Joseph, KC Chung, AX Zhang, S Ler, MA Prakesch, ... Journal of medicinal chemistry 64 (15), 11129-11147, 2021 | 23 | 2021 |
| Discovery of the apoptosis-inducing activity and high accumulation of the butenolides, menisdaurilide and aquilegiolide, in Dicentra spectabilis J McNulty, J Poloczek, V Larichev, NH Werstiuk, C Griffin, S Pandey Planta medica 73 (15), 1543-1547, 2007 | 23 | 2007 |
| Scalable Synthesis of Amaryllidaceae Isocarbostyril Alkaloids from Enantiomerically Pure 7-Azabicyclo [2.2. 1] heptanone Scaffold: Total Synthesis of (+)-7-Deoxypancratistatin G Pandey, R Fernandes, D Dey Synlett 29 (06), 805-809, 2018 | 10 | 2018 |
| Pancratistatin: a novel highly selective anti-cancer agent that induces apoptosis by the activation of membrane-Fas-receptor associated caspase-3 C Griffin, J McNulty, C Hamm, S Pandey Trends in Cell Apoptosis Research, 93-110, 2007 | 8 | 2007 |
| Primary research Pancratistatin induces apoptosis in clinical leukemia samples with minimal effect on non-cancerous peripheral blood mononuclear cells C Griffin, C Hamm, J McNulty, S Pandey Cancer Cell International 10, 1-7, 2010 | 5 | 2010 |
