Expanded encyclopaedias of DNA elements in the human and mouse genomes JE Moore, MJ Purcaro, HE Pratt, CB Epstein, N Shoresh, J Adrian, T Kawli, ... Nature 583 (7818), 699-710, 2020 | 1258 | 2020 |
Distinct properties of cell-type-specific and shared transcription factor binding sites J Gertz, D Savic, KE Varley, EC Partridge, A Safi, P Jain, GM Cooper, ... Molecular cell 52 (1), 25-36, 2013 | 336 | 2013 |
Transcriptional enhancers in development and disease NJ Sakabe, D Savic, MA Nobrega Genome biology 13, 1-11, 2012 | 174 | 2012 |
Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism D Savic, H Ye, I Aneas, SY Park, GI Bell, MA Nobrega Genome research 21 (9), 1417-1425, 2011 | 160 | 2011 |
NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells SW Paugh, EJ Bonten, D Savic, LB Ramsey, WE Thierfelder, P Gurung, ... Nature genetics 47 (6), 607-614, 2015 | 158 | 2015 |
CETCh-seq: CRISPR epitope tagging ChIP-seq of DNA-binding proteins D Savic, EC Partridge, KM Newberry, SB Smith, SK Meadows, BS Roberts, ... Genome research 25 (10), 1581-1589, 2015 | 144 | 2015 |
CCCTC-binding factor translates interleukin 2-and α-ketoglutarate-sensitive metabolic changes in T cells into context-dependent gene programs DA Chisolm, D Savic, AJ Moore, A Ballesteros-Tato, B León, ... Immunity 47 (2), 251-267. e7, 2017 | 100 | 2017 |
Occupancy maps of 208 chromatin-associated proteins in one human cell type EC Partridge, SB Chhetri, JW Prokop, RC Ramaker, CS Jansen, ST Goh, ... Nature 583 (7818), 720-728, 2020 | 97 | 2020 |
Perspectives on ENCODE MP Snyder, TR Gingeras, JE Moore, Z Weng, MB Gerstein, B Ren, ... Nature 583 (7818), 693-698, 2020 | 96 | 2020 |
Batf pioneers the reorganization of chromatin in developing effector T cells via Ets1-dependent recruitment of Ctcf D Pham, CE Moseley, M Gao, D Savic, CJ Winstead, M Sun, BL Kee, ... Cell reports 29 (5), 1203-1220. e7, 2019 | 83 | 2019 |
Genomic regulation of invasion by STAT3 in triple negative breast cancer JM McDaniel, KE Varley, J Gertz, DS Savic, BS Roberts, SK Bailey, ... Oncotarget 8 (5), 8226, 2017 | 75 | 2017 |
Integrative genomic analyses reveal mechanisms of glucocorticoid resistance in acute lymphoblastic leukemia RJ Autry, SW Paugh, R Carter, L Shi, J Liu, DC Ferguson, CE Lau, ... Nature cancer 1 (3), 329-344, 2020 | 51 | 2020 |
Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation D Savic, RC Ramaker, BS Roberts, EC Dean, TC Burwell, SK Meadows, ... Genome medicine 8, 1-16, 2016 | 45 | 2016 |
Evidence of non-pancreatic beta cell-dependent roles of Tcf7l2 in the regulation of glucose metabolism in mice KA Bailey, D Savic, M Zielinski, SY Park, L Wang, P Witkowski, M Brady, ... Human molecular genetics 24 (6), 1646-1654, 2015 | 40 | 2015 |
Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/enhancer-binding protein beta binding sites D Savic, BS Roberts, JB Carleton, EC Partridge, MA White, BA Cohen, ... Genome research 25 (12), 1791-1800, 2015 | 34 | 2015 |
Mapping genome-wide transcription factor binding sites in frozen tissues D Savic, J Gertz, P Jain, GM Cooper, RM Myers Epigenetics & chromatin 6, 1-10, 2013 | 34 | 2013 |
Modulation of Tcf7l2 Expression Alters Behavior in Mice D Savic, MG Distler, G Sokoloff, NA Shanahan, SC Dulawa, AA Palmer, ... PloS one 6 (10), e26897, 2011 | 33 | 2011 |
Bromodomain-selective BET inhibitors are potent antitumor agents against MYC-driven pediatric cancer PJ Slavish, L Chi, MK Yun, L Tsurkan, NE Martinez, B Jonchere, SC Chai, ... Cancer research 80 (17), 3507-3518, 2020 | 31 | 2020 |
Perspectives on ENCODE F Abascal, R Acosta, NJ Addleman, J Adrian, V Afzal, B Aken, JA Akiyama Nature 583 (7818), 693-699, 2020 | 25 | 2020 |
In vitro scan for enhancers at the TCF7L2 locus D Savic, SY Park, KA Bailey, GI Bell, MA Nobrega Diabetologia 56, 121-125, 2013 | 23 | 2013 |