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Tim E. Moors
Tim E. Moors
Postdoctoral Research Fellow, Harvard Medical School and Brigham and Women's Hospital
在 bwh.harvard.edu 的电子邮件经过验证
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引用次数
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Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes
SH Shahmoradian, AJ Lewis, C Genoud, J Hench, TE Moors, PP Navarro, ...
Nature neuroscience 22 (7), 1099-1109, 2019
8102019
Therapeutic potential of autophagy-enhancing agents in Parkinson’s disease
TE Moors, JJM Hoozemans, A Ingrassia, T Beccari, L Parnetti, ...
Molecular neurodegeneration 12, 1-18, 2017
3142017
Microglial phenotypes and toll-like receptor 2 in the substantia nigra and hippocampus of incidental Lewy body disease cases and Parkinson’s disease patients
KJ Doorn, T Moors, B Drukarch, WDJ van de Berg, PJ Lucassen, ...
Acta neuropathologica communications 2, 1-17, 2014
3032014
Lysosomal dysfunction and α‐Synuclein aggregation in Parkinson's disease: diagnostic links
T Moors, S Paciotti, D Chiasserini, P Calabresi, L Parnetti, T Beccari, ...
Movement Disorders 31 (6), 791-801, 2016
1552016
Characterization of Brain Lysosomal Activities in GBA-Related and Sporadic Parkinson’s Disease and Dementia with Lewy Bodies
TE Moors, S Paciotti, A Ingrassia, M Quadri, G Breedveld, A Tasegian, ...
Molecular neurobiology 56, 1344-1355, 2019
1282019
The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson’s disease brain as revealed by multicolor STED microscopy
TE Moors, CA Maat, D Niedieker, D Mona, D Petersen, ...
Acta neuropathologica 142, 423-448, 2021
872021
Path mediation analysis reveals GBA impacts Lewy body disease status by increasing α-synuclein levels
AL Gündner, G Duran-Pacheco, S Zimmermann, I Ruf, T Moors, ...
Neurobiology of disease 121, 205-213, 2019
572019
Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity
N Ramalingam, SX Jin, TE Moors, L Fonseca-Ornelas, K Shimanaka, ...
npj Parkinson's Disease 9 (1), 4, 2023
442023
Lewy pathology in Parkinson’s disease consists of a crowded organellar, membranous medley
SH Shahmoradian, AJ Lewis, C Genoud, J Hench, T Moors, PP Navarro, ...
biorxiv, 137976, 2017
332017
Wild-type GBA1 increases the α-synuclein tetramer–monomer ratio, reduces lipid-rich aggregates, and attenuates motor and cognitive deficits in mice
KE Glajch, TE Moors, Y Chen, PA Bechade, AY Nam, MM Rajsombath, ...
Proceedings of the National Academy of Sciences 118 (31), e2103425118, 2021
272021
Subcellular orchestration of alpha-synuclein variants in Parkinson’s disease brains revealed by 3D multicolor STED microscopy
TE Moors, CA Maat, D Niedieker, D Mona, D Petersen, ...
bioRxiv, 470476, 2018
122018
Detailed structural orchestration of Lewy pathology in Parkinson’s disease as revealed by 3D multicolor STED microscopy
TE Moors, CA Maat, D Niedieker, D Mona, D Petersen, ...
Biorxiv, 470476, 2018
122018
Multi-platform quantitation of alpha-synuclein human brain proteoforms suggests disease-specific biochemical profiles of synucleinopathies
TE Moors, D Mona, S Luehe, G Duran-Pacheco, L Spycher, O Mundigl, ...
Acta neuropathologica communications 10 (1), 82, 2022
102022
The orchestration of subcellular alpha-synuclein pathology in the Parkinson’s disease brain revealed by STED microscopy
TE Moors, CA Maat, D Niedieker, D Mona, D Petersen, ...
bioRxiv, 2018
92018
Alterations in sub-axonal architecture between normal aging and Parkinson’s diseased human brains using label-free cryogenic X-ray nanotomography
HT Tran, EHR Tsai, AJ Lewis, T Moors, J Bol, I Rostami, A Diaz, AJ Jonker, ...
Frontiers in neuroscience 14, 570019, 2020
72020
Origin of α-mannosidase activity in CSF
A Tasegian, S Paciotti, MR Ceccarini, M Codini, T Moors, D Chiasserini, ...
The international journal of biochemistry & cell biology 87, 34-37, 2017
72017
Lewy pathology in Parkinson’s disease consists of a crowded organellar membranous medley. bioRxiv 137976
SH Shahmoradian, C Genoud, A Graff-Meyer, J Hench, T Moors, ...
72017
Increased palmitoylation improves estrogen receptor alpha–dependent hippocampal synaptic deficits in a mouse model of synucleinopathy
TE Moors, S Li, TD McCaffery, GPH Ho, PA Bechade, LN Pham, ...
Science Advances 9 (46), eadj1454, 2023
32023
Defining a Lewy Body: Running Up the Hill of Shifting Definitions and Evolving Concepts
TE Moors, D Milovanovic
Journal of Parkinson's Disease, 1-17, 2024
22024
Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson’s disease phenotypes
S Nuber, X Zhang, TD McCaffery, TE Moors, MA Adom, WN Hahn, ...
npj Parkinson's Disease 10 (1), 47, 2024
12024
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