FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption BL Clifford, LR Sedgeman, KJ Williams, P Morand, A Cheng, KE Jarrett, ... Cell metabolism 33 (8), 1671-1684. e4, 2021 | 218 | 2021 |
Probing the Metabolic Network in Bloodstream-Form Trypanosoma brucei Using Untargeted Metabolomics with Stable Isotope Labelled Glucose DJ Creek, M Mazet, F Achcar, J Anderson, DH Kim, R Kamour, P Morand, ... PLoS pathogens 11 (3), e1004689, 2015 | 137 | 2015 |
An integrative systems genetic analysis of mammalian lipid metabolism BL Parker, AC Calkin, MM Seldin, MF Keating, EJ Tarling, P Yang, ... Nature 567 (7747), 187-193, 2019 | 117 | 2019 |
Revisiting the Central Metabolism of the Bloodstream Forms of Trypanosoma brucei: Production of Acetate in the Mitochondrion Is Essential for Parasite Viability M Mazet, P Morand, M Biran, G Bouyssou, P Courtois, S Daulouède, ... PLOS neglected tropical diseases 7 (12), e2587, 2013 | 113 | 2013 |
The threonine degradation pathway of the Trypanosoma brucei procyclic form: the main carbon source for lipid biosynthesis is under metabolic control Y Millerioux, C Ebikeme, M Biran, P Morand, G Bouyssou, IM Vincent, ... Molecular microbiology 90 (1), 114-129, 2013 | 78 | 2013 |
Cytosolic NADPH homeostasis in glucose-starved procyclic Trypanosoma brucei relies on malic enzyme and the pentose phosphate pathway fed by gluconeogenic flux S Allmann, P Morand, C Ebikeme, L Gales, M Biran, J Hubert, A Brennand, ... Journal of Biological Chemistry 288 (25), 18494-18505, 2013 | 78 | 2013 |
RNA-binding protein ZFP36L1 maintains posttranscriptional regulation of bile acid metabolism EJ Tarling, BL Clifford, J Cheng, P Morand, A Cheng, E Lester, T Sallam, ... The Journal of clinical investigation 127 (10), 3741-3754, 2017 | 55 | 2017 |
ATP synthesis-coupled and-uncoupled acetate production from acetyl-CoA by mitochondrial acetate: succinate CoA-transferase and acetyl-CoA thioesterase in Trypanosoma Y Millerioux, P Morand, M Biran, M Mazet, P Moreau, M Wargnies, ... Journal of Biological Chemistry 287 (21), 17186-17197, 2012 | 54 | 2012 |
Ablation of succinate production from glucose metabolism in the procyclic trypanosomes induces metabolic switches to the glycerol 3-phosphate/dihydroxyacetone phosphate shuttle … C Ebikeme, J Hubert, M Biran, G Gouspillou, P Morand, N Plazolles, ... Journal of Biological Chemistry 285 (42), 32312-32324, 2010 | 53 | 2010 |
Contribution of pyruvate phosphate dikinase in the maintenance of the glycosomal ATP/ADP balance in the Trypanosoma brucei procyclic form K Deramchia, P Morand, M Biran, Y Millerioux, M Mazet, M Wargnies, ... Journal of Biological Chemistry 289 (25), 17365-17378, 2014 | 41 | 2014 |
Gluconeogenesis is essential for trypanosome development in the tsetse fly vector M Wargnies, E Bertiaux, E Cahoreau, N Ziebart, A Crouzols, P Morand, ... PLoS pathogens 14 (12), e1007502, 2018 | 36 | 2018 |
The characterization and evolutionary relationships of a trypanosomal thiolase M Mazet, RK Harijan, TR Kiema, AM Haapalainen, P Morand, J Morales, ... International journal for parasitology 41 (12), 1273-1283, 2011 | 17 | 2011 |
Real‐time imaging of sodium glucose transporter (SGLT1) trafficking and activity in single cells C Ghezzi, G Calmettes, P Morand, B Ribalet, S John Physiological reports 5 (3), e13062, 2017 | 12 | 2017 |
Glycerol suppresses glucose consumption in trypanosomes through metabolic contest S Allmann, M Wargnies, N Plazolles, E Cahoreau, M Biran, P Morand, ... PLoS Biology 19 (8), e3001359, 2021 | 9 | 2021 |
RNF130 regulates LDLR availability and plasma LDL cholesterol levels BL Clifford, KE Jarrett, J Cheng, A Cheng, M Seldin, P Morand, R Lee, ... Circulation research 132 (7), 849-863, 2023 | 2 | 2023 |
Streptococcus pyogenes Cas9 ribonucleoprotein delivery for efficient, rapid and marker‐free gene editing in Trypanosoma and Leishmania C Asencio, P Hervé, P Morand, Q Oliveres, CA Morel, V Prouzet‐Mauleon, ... Molecular Microbiology, 2024 | 1 | 2024 |
Intestinal deletion of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase promotes expansion of the resident stem cell compartment AM Doerfler, J Han, KE Jarrett, L Tang, A Jain, A Saltzman, M De Giorgi, ... Arteriosclerosis, thrombosis, and vascular biology 42 (4), 381-394, 2022 | 1 | 2022 |
OFF-THE-SHELF BIOREACTOR PRODUCED, IPSC-DERIVED NEURAL MICROTISSUES CONTAINING DOPAMINERGIC NEURONS INNERVATE THE STRIATUM AND NORMALIZE BEHAVIOR IN A PARKINSON RAT MODEL N Prudon, L Cordero-Espinoza, C Morel, M Lepleux, B Gurchenkov, ... Cytotherapy 26 (6), S229, 2024 | | 2024 |
Off-the-shelf Bioreactor Produced, iPSC-derived Neural Microtissues Containing Dopaminergic Neurons Innervate the Striatum and Normalize Behavior in a Parkinson Rat Model (P4-3 … N Prudon, L Cordero-Espinoza, C Morel, M Lepleux, B Gurchenkov, ... Neurology 102 (17_supplement_1), 7235, 2024 | | 2024 |
iPSC: MICROTISSUE CELL THERAPY FOR PARKINSON’S DISEASE: SCALE-UP IN BIOREACTORS AND LATEST IN VIVO RESULTS M Feyeux, L Cordero-Espinoza, L Milvoy, P Morand, C Morel, M Abarkan, ... Cytotherapy 25 (6), S277, 2023 | | 2023 |