Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent K Fujimori, M Ishikawa, A Otomo, N Atsuta, R Nakamura, T Akiyama, ... Nature medicine 24 (10), 1579-1589, 2018 | 409 | 2018 |
Establishment of in vitro FUS-associated familial amyotrophic lateral sclerosis model using human induced pluripotent stem cells N Ichiyanagi, K Fujimori, M Yano, C Ishihara-Fujisaki, T Sone, T Akiyama, ... Stem cell reports 6 (4), 496-510, 2016 | 100 | 2016 |
Functional neurons generated from T cell-derived induced pluripotent stem cells for neurological disease modeling T Matsumoto, K Fujimori, T Andoh-Noda, T Ando, N Kuzumaki, ... Stem cell reports 6 (3), 422-435, 2016 | 71 | 2016 |
Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons T Akiyama, N Suzuki, M Ishikawa, K Fujimori, T Sone, J Kawada, ... EBioMedicine 45, 362-378, 2019 | 68 | 2019 |
The pathogenesis linked to coenzyme Q10 insufficiency in iPSC-derived neurons from patients with multiple-system atrophy FK Nakamoto, S Okamoto, J Mitsui, T Sone, M Ishikawa, Y Yamamoto, ... Scientific reports 8 (1), 14215, 2018 | 60 | 2018 |
Differential gene expression profiles in neurons generated from lymphoblastoid B-cell line-derived iPS cells from monozygotic twin cases with treatment-resistant schizophrenia … T Nakazawa, M Kikuchi, M Ishikawa, H Yamamori, K Nagayasu, ... Schizophrenia research 181, 75-82, 2017 | 55 | 2017 |
Long-term selective stimulation of transplanted neural stem/progenitor cells for spinal cord injury improves locomotor function M Kawai, K Imaizumi, M Ishikawa, S Shibata, M Shinozaki, T Shibata, ... Cell Reports 37 (8), 2021 | 54 | 2021 |
In vitro modeling of the bipolar disorder and schizophrenia using patient-derived induced pluripotent stem cells with copy number variations of PCDH15 and RELN T Ishii, M Ishikawa, K Fujimori, T Maeda, I Kushima, Y Arioka, D Mori, ... Eneuro 6 (5), 2019 | 52 | 2019 |
Involvement of the serum response factor coactivator megakaryoblastic leukemia (MKL) in the activin-regulated dendritic complexity of rat cortical neurons M Ishikawa, N Nishijima, J Shiota, H Sakagami, K Tsuchida, M Mizukoshi, ... Journal of Biological Chemistry 285 (43), 32734-32743, 2010 | 49 | 2010 |
Human astrocytes model derived from induced pluripotent stem cells N Leventoux, S Morimoto, K Imaizumi, Y Sato, S Takahashi, K Mashima, ... Cells 9 (12), 2680, 2020 | 46 | 2020 |
Developmental expression of the SRF co‐activator MAL in brain: role in regulating dendritic morphology J Shiota, M Ishikawa, H Sakagami, M Tsuda, JM Baraban, A Tabuchi Journal of neurochemistry 98 (6), 1778-1788, 2006 | 46 | 2006 |
Non-viral induction of transgene-free iPSCs from somatic fibroblasts of multiple mammalian species S Yoshimatsu, M Nakajima, A Iguchi, T Sanosaka, T Sato, M Nakamura, ... Stem cell reports 16 (4), 754-770, 2021 | 39 | 2021 |
miRNA-based rapid differentiation of purified neurons from hPSCs advancestowards quick screening for neuronal disease phenotypes in vitro M Ishikawa, T Aoyama, S Shibata, T Sone, H Miyoshi, H Watanabe, ... Cells 9 (3), 532, 2020 | 35 | 2020 |
Single-cell trajectory analysis of human homogenous neurons carrying a rare RELN variant Y Arioka, E Shishido, H Kubo, I Kushima, A Yoshimi, H Kimura, K Ishizuka, ... Translational psychiatry 8 (1), 129, 2018 | 34 | 2018 |
DCTN1 binds to TDP-43 and regulates TDP-43 aggregation M Deshimaru, M Kinoshita-Kawada, K Kubota, T Watanabe, Y Tanaka, ... International journal of molecular sciences 22 (8), 3985, 2021 | 29 | 2021 |
Deltamethrin, a type II pyrethroid insecticide, has neurotrophic effects on neurons with continuous activation of the Bdnf promoter D Ihara, M Fukuchi, D Honma, I Takasaki, M Ishikawa, A Tabuchi, ... Neuropharmacology 62 (2), 1091-1098, 2012 | 28 | 2012 |
Application of induced pluripotent stem cells in epilepsy S Hirose, Y Tanaka, M Shibata, Y Kimura, M Ishikawa, N Higurashi, ... Molecular and Cellular Neuroscience 108, 103535, 2020 | 24 | 2020 |
Impaired neuronal activity and differential gene expression in STXBP1 encephalopathy patient iPSC-derived GABAergic neurons E Ichise, T Chiyonobu, M Ishikawa, Y Tanaka, M Shibata, T Tozawa, ... Human molecular genetics 30 (14), 1337-1348, 2021 | 21 | 2021 |
Generation of D1-1 TALEN isogenic control cell line from Dravet syndrome patient iPSCs using TALEN-mediated editing of the SCN1A gene Y Tanaka, T Sone, N Higurashi, T Sakuma, S Suzuki, M Ishikawa, ... Stem Cell Research 28, 100-104, 2018 | 18 | 2018 |
Synaptic localisation of SRF coactivators, MKL1 and MKL2, and their role in dendritic spine morphology M Kaneda, H Sakagami, Y Hida, T Ohtsuka, N Satou, Y Ishibashi, ... Scientific reports 8 (1), 727, 2018 | 18 | 2018 |