Glutaminolysis and fumarate accumulation integrate immunometabolic and epigenetic programs in trained immunity RJW Arts, B Novakovic, R Ter Horst, A Carvalho, S Bekkering, ... Cell metabolism 24 (6), 807-819, 2016 | 707 | 2016 |
Metabolic induction of trained immunity through the mevalonate pathway S Bekkering, RJW Arts, B Novakovic, I Kourtzelis, CDCC van der Heijden, ... Cell 172 (1), 135-146. e9, 2018 | 605 | 2018 |
Oxidized low-density lipoprotein induces long-term proinflammatory cytokine production and foam cell formation via epigenetic reprogramming of monocytes S Bekkering, J Quintin, LAB Joosten, JWM van der Meer, MG Netea, ... Arteriosclerosis, thrombosis, and vascular biology 34 (8), 1731-1738, 2014 | 579 | 2014 |
Oxidized phospholipids on lipoprotein (a) elicit arterial wall inflammation and an inflammatory monocyte response in humans FM van der Valk, S Bekkering, J Kroon, C Yeang, J Van den Bossche, ... Circulation 134 (8), 611-624, 2016 | 513 | 2016 |
Trained immunity, tolerance, priming and differentiation: distinct immunological processes M Divangahi, P Aaby, SA Khader, LB Barreiro, S Bekkering, T Chavakis, ... Nature immunology 22 (1), 2-6, 2021 | 382 | 2021 |
In Vitro Experimental Model of Trained Innate Immunity in Human Primary Monocytes S Bekkering, BA Blok, LAB Joosten, NP Riksen, R van Crevel, MG Netea Clinical and Vaccine Immunology 23 (12), 926-933, 2016 | 302 | 2016 |
Trained immunity: reprogramming innate immunity in health and disease S Bekkering, J Domínguez-Andrés, LAB Joosten, NP Riksen, MG Netea Annual review of immunology 39 (1), 667-693, 2021 | 201 | 2021 |
Innate immune cell activation and epigenetic remodeling in symptomatic and asymptomatic atherosclerosis in humans in vivo S Bekkering, I van den Munckhof, T Nielen, E Lamfers, C Dinarello, ... Atherosclerosis 254, 228-236, 2016 | 198 | 2016 |
Joosten LAB, van der Meer JWM, Netea MG, Riksen NP. Oxidized low-density lipoprotein induces long-term proinflammatory cytokine production and foam cell formation via … S Bekkering, J Quintin Arterioscler Thromb Vasc Biol 34 (8), 1731-8, 2014 | 135 | 2014 |
Trained innate immunity as a novel mechanism linking infection and the development of atherosclerosis J Leentjens, S Bekkering, LAB Joosten, MG Netea, DP Burgner, ... Circulation research 122 (5), 664-669, 2018 | 122 | 2018 |
Remnant cholesterol elicits arterial wall inflammation and a multilevel cellular immune response in humans SJ Bernelot Moens, SL Verweij, JG Schnitzler, LCA Stiekema, M Bos, ... Arteriosclerosis, thrombosis, and vascular biology 37 (5), 969-975, 2017 | 116 | 2017 |
Treatment with statins does not revert trained immunity in patients with familial hypercholesterolemia S Bekkering, LCA Stiekema, SB Moens, SL Verweij, B Novakovic, ... Cell metabolism 30 (1), 1-2, 2019 | 113 | 2019 |
Effects of oral butyrate supplementation on inflammatory potential of circulating peripheral blood mononuclear cells in healthy and obese males MCP Cleophas, JM Ratter, S Bekkering, J Quintin, K Schraa, ES Stroes, ... Scientific reports 9 (1), 775, 2019 | 107 | 2019 |
Long-term activation of the innate immune system in atherosclerosis A Christ, S Bekkering, E Latz, NP Riksen Seminars in Immunology 28 (4), 384-393, 2016 | 96 | 2016 |
Plasma cholesteryl ester transfer protein is predominantly derived from Kupffer cells Y Wang, S van der Tuin, N Tjeerdema, AD van Dam, SS Rensen, ... Hepatology 62 (6), 1710-1722, 2015 | 91 | 2015 |
Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein ST Keating, L Groh, K Thiem, S Bekkering, Y Li, V Matzaraki, ... Journal of Molecular Medicine 98, 819-831, 2020 | 86 | 2020 |
Diabetes and overweight/obesity are independent, nonadditive risk factors for in-hospital severity of COVID-19: an international, multicenter retrospective meta-analysis DK Longmore, JE Miller, S Bekkering, C Saner, E Mifsud, Y Zhu, R Saffery, ... Diabetes Care 44 (6), 1281-1290, 2021 | 84 | 2021 |
The epigenetic memory of monocytes and macrophages as a novel drug target in atherosclerosis S Bekkering, LAB Joosten, JWM van der Meer, MG Netea, NP Riksen Clinical therapeutics 37 (4), 914-923, 2015 | 80 | 2015 |
Trained innate immunity and atherosclerosis S Bekkering, LAB Joosten, JWM van der Meer, MG Netea, NP Riksen Current opinion in lipidology 24 (6), 487-492, 2013 | 77 | 2013 |
Oral butyrate does not affect innate immunity and islet autoimmunity in individuals with longstanding type 1 diabetes: a randomised controlled trial PF de Groot, T Nikolic, S Imangaliyev, S Bekkering, G Duinkerken, ... Diabetologia 63, 597-610, 2020 | 76 | 2020 |