Cardiac myocyte-specific excision of the β1 integrin gene results in myocardial fibrosis and cardiac failure SY Shai, AE Harpf, CJ Babbitt, MC Jordan, MC Fishbein, J Chen, ... Circulation research 90 (4), 458-464, 2002 | 332 | 2002 |
Chemoimmunotherapy reinduction with epratuzumab in children with acute lymphoblastic leukemia in marrow relapse: a Children's Oncology Group Pilot Study EA Raetz, MS Cairo, MJ Borowitz, SM Blaney, MD Krailo, TA Leil, JM Reid, ... Journal of Clinical Oncology 26 (22), 3756-3762, 2008 | 253 | 2008 |
GABAA receptor-associated protein traffics GABAA receptors to the plasma membrane in neurons TA Leil, ZW Chen, CSS Chang, RW Olsen Journal of Neuroscience 24 (50), 11429-11438, 2004 | 217 | 2004 |
Quantification of apixaban's therapeutic utility in prevention of venous thromboembolism: selection of phase III trial dose TA Leil, Y Feng, L Zhang, A Paccaly, P Mohan, M Pfister CliniCal pharmaCology & TherapeuTiCs 88 (3), 375-382, 2010 | 110 | 2010 |
Quantitative systems pharmacology can reduce attrition and improve productivity in pharmaceutical research and development TA Leil, R Bertz Frontiers in pharmacology 5, 247, 2014 | 72 | 2014 |
GABAA receptor-associated protein regulates GABAA receptor cell-surface number in Xenopus laevis oocytes ZW Chen, CSS Chang, TA Leil, R Olcese, RW Olsen Molecular pharmacology 68 (1), 152-159, 2005 | 69 | 2005 |
C-terminal modification is required for GABARAP-mediated GABAA receptor trafficking ZW Chen, CSS Chang, TA Leil, RW Olsen Journal of Neuroscience 27 (25), 6655-6663, 2007 | 65 | 2007 |
Population pharmacokinetics of apixaban in subjects with nonvalvular atrial fibrillation B Cirincione, K Kowalski, J Nielsen, A Roy, N Thanneer, W Byon, R Boyd, ... CPT: pharmacometrics & systems pharmacology 7 (11), 728-738, 2018 | 64 | 2018 |
Genes regulated by learning in the hippocampus TA Leil, A Ossadtchi, TE Nichols, RM Leahy, DJ Smith Journal of neuroscience research 71 (6), 763-768, 2003 | 62 | 2003 |
Use of systems pharmacology modeling to elucidate the operating characteristics of SGLT1 and SGLT2 in renal glucose reabsorption in humans Y Lu, SC Griffen, DW Boulton, TA Leil Frontiers in pharmacology 5, 274, 2014 | 58 | 2014 |
Identification and characterization of genetic variation in the folylpolyglutamate synthase gene TA Leil, C Endo, AA Adjei, GK Dy, OE Salavaggione, JR Reid, MM Ames, ... Cancer research 67 (18), 8772-8782, 2007 | 57 | 2007 |
Finding new candidate genes for learning and memory TA Leil, A Ossadtchi, JS Cortes, RM Leahy, DJ Smith Journal of neuroscience research 68 (2), 127-137, 2002 | 52 | 2002 |
QSP toolbox: computational implementation of integrated workflow components for deploying multi-scale mechanistic models Y Cheng, CJ Thalhauser, S Smithline, J Pagidala, M Miladinov, ... The AAPS journal 19, 1002-1016, 2017 | 47 | 2017 |
Model‐based exposure–response analysis of apixaban to quantify bleeding risk in special populations of subjects undergoing orthopedic surgery TA Leil, C Frost, X Wang, M Pfister, F LaCreta CPT: Pharmacometrics & Systems Pharmacology 3 (9), 1-9, 2014 | 45 | 2014 |
Investigating transporter‐mediated drug‐drug interactions using a physiologically based pharmacokinetic model of rosuvastatin Q Wang, M Zheng, T Leil CPT: Pharmacometrics & Systems Pharmacology 6 (4), 228-238, 2017 | 37 | 2017 |
Evaluation of 4β‐Hydroxycholesterol as a Clinical Biomarker of CYP3A4 Drug Interactions Using a Bayesian Mechanism–Based Pharmacometric Model TA Leil, S Kasichayanula, DW Boulton, F LaCreta CPT: pharmacometrics & systems pharmacology 3 (6), 1-10, 2014 | 34 | 2014 |
Tamoxifen Induces Expression of Immune Response–Related Genes in Cultured Normal Human Mammary Epithelial Cells LJ Schild-Hay, TA Leil, RL Divi, OA Olivero, A Weston, MC Poirier Cancer research 69 (3), 1150-1155, 2009 | 31 | 2009 |
Neurotrophin-4 is required for tolerance to morphine in the mouse DJ Smith, TA Leil, X Liu Neuroscience letters 340 (2), 103-106, 2003 | 30 | 2003 |
Children’s Oncology Group Pilot Study. Chemoimmunotherapy reinduction with epratuzumab in children with acute lymphoblastic leukemia in marrow relapse: a Children’s Oncology … EA Raetz, MS Cairo, MJ Borowitz, SM Blaney, MD Krailo, TA Leil, JM Reid, ... J Clin Oncol 26 (22), 3756-3762, 2008 | 27 | 2008 |
Virtual populations for quantitative systems pharmacology models Y Cheng, R Straube, AE Alnaif, L Huang, TA Leil, BJ Schmidt Systems Medicine, 129-179, 2022 | 25 | 2022 |