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Lance Cadang
Lance Cadang
Scientist 3, Genentech
在 gene.com 的电子邮件经过验证
标题
引用次数
引用次数
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Fc galactosylation follows consecutive reaction kinetics and enhances immunoglobulin G hexamerization for complement activation
B Wei, X Gao, L Cadang, S Izadi, P Liu, HM Zhang, E Hecht, J Shim, ...
MAbs 13 (1), 1893427, 2021
502021
Development of an ion pairing reversed-phase liquid chromatography-mass spectrometry method for characterization of clustered regularly interspaced short palindromic repeats …
B Wei, J Wang, L Cadang, A Goyon, B Chen, F Yang, K Zhang
Journal of Chromatography A 1665, 462839, 2022
132022
Versatile LC–MS-Based workflow with robust 0.1 ppm sensitivity for identifying residual HCPs in biotherapeutic products
F Yang, D Li, R Kufer, L Cadang, J Zhang, L Dai, J Guo, S Wohlrab, ...
Analytical Chemistry 94 (2), 723-731, 2021
122021
Challenges and strategies for a thorough characterization of antibody acidic charge variants
YD Liu, L Cadang, K Bol, X Pan, K Tschudi, M Jazayri, J Camperi, ...
Bioengineering 9 (11), 641, 2022
112022
Discovery of a dual pathway aggregation mechanism for a therapeutic constrained peptide
T Chen, S Tang, ES Hecht, CW Yen, N Andersen, S Chin, L Cadang, ...
Journal of Pharmaceutical Sciences 110 (6), 2362-2371, 2021
42021
CD3 Target Affinity Chromatography Mass Spectrometry as a New Tool for Function–Structure Characterization of T-Cell Engaging Bispecific Antibody Proteoforms and Product …
S Lippold, M Hook, C Spick, A Knaupp, K Whang, F Ruperti, L Cadang, ...
Analytical Chemistry 95 (4), 2260-2268, 2023
22023
Internal Fragment Ions from Higher Energy Collision Dissociation Enable the Glycoform-Resolved Asn325 Deamidation Assessment of Antibodies by Middle-Down Mass Spectrometry
S Lippold, L Cadang, T Schlothauer, F Yang
Analytical Chemistry 95 (45), 16447-16452, 2023
12023
Function-structure approach reveals novel insights on the interplay of Immunoglobulin G 1 proteoforms and Fc gamma receptor IIa allotypes
S Lippold, K Mistry, S Lenka, K Whang, P Liu, S Pitschi, F Kuhne, ...
Frontiers in Immunology 14, 1260446, 2023
12023
Identification and quantitation of residual host cell proteins in protein samples
J Guo, R Kufer, D Li, F Yang, IH Yuk, J Zhang, LJ Cadang, L Dai
US Patent App. 18/526,020, 2024
2024
Probing the Protein–Excipient Interaction in the Orally Delivered Protein by Solid-State Hydrogen–Deuterium Exchange Mass Spectrometry and Molecular Dynamics
X Pan, S Lenka, J Davis, K Nagapudi, P Mantik, M Saggu, L Dai, ...
Analytical Chemistry 96 (2), 802-809, 2023
2023
A Highly Efficient Workflow for Detecting and Identifying Sequence Variants in Therapeutic Proteins with a High Resolution LC-MS/MS Method
L Cadang, CYJ Tam, BN Moore, J Fichtl, F Yang
Molecules 28 (8), 3392, 2023
2023
Compositions and methods for stabilizing protein-containing formulations
YT Adem, LJ Cadang
US Patent App. 17/490,877, 2022
2022
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