Fc galactosylation follows consecutive reaction kinetics and enhances immunoglobulin G hexamerization for complement activation B Wei, X Gao, L Cadang, S Izadi, P Liu, HM Zhang, E Hecht, J Shim, ... MAbs 13 (1), 1893427, 2021 | 50 | 2021 |
Development of an ion pairing reversed-phase liquid chromatography-mass spectrometry method for characterization of clustered regularly interspaced short palindromic repeats … B Wei, J Wang, L Cadang, A Goyon, B Chen, F Yang, K Zhang Journal of Chromatography A 1665, 462839, 2022 | 13 | 2022 |
Versatile LC–MS-Based workflow with robust 0.1 ppm sensitivity for identifying residual HCPs in biotherapeutic products F Yang, D Li, R Kufer, L Cadang, J Zhang, L Dai, J Guo, S Wohlrab, ... Analytical Chemistry 94 (2), 723-731, 2021 | 12 | 2021 |
Challenges and strategies for a thorough characterization of antibody acidic charge variants YD Liu, L Cadang, K Bol, X Pan, K Tschudi, M Jazayri, J Camperi, ... Bioengineering 9 (11), 641, 2022 | 11 | 2022 |
Discovery of a dual pathway aggregation mechanism for a therapeutic constrained peptide T Chen, S Tang, ES Hecht, CW Yen, N Andersen, S Chin, L Cadang, ... Journal of Pharmaceutical Sciences 110 (6), 2362-2371, 2021 | 4 | 2021 |
CD3 Target Affinity Chromatography Mass Spectrometry as a New Tool for Function–Structure Characterization of T-Cell Engaging Bispecific Antibody Proteoforms and Product … S Lippold, M Hook, C Spick, A Knaupp, K Whang, F Ruperti, L Cadang, ... Analytical Chemistry 95 (4), 2260-2268, 2023 | 2 | 2023 |
Internal Fragment Ions from Higher Energy Collision Dissociation Enable the Glycoform-Resolved Asn325 Deamidation Assessment of Antibodies by Middle-Down Mass Spectrometry S Lippold, L Cadang, T Schlothauer, F Yang Analytical Chemistry 95 (45), 16447-16452, 2023 | 1 | 2023 |
Function-structure approach reveals novel insights on the interplay of Immunoglobulin G 1 proteoforms and Fc gamma receptor IIa allotypes S Lippold, K Mistry, S Lenka, K Whang, P Liu, S Pitschi, F Kuhne, ... Frontiers in Immunology 14, 1260446, 2023 | 1 | 2023 |
Identification and quantitation of residual host cell proteins in protein samples J Guo, R Kufer, D Li, F Yang, IH Yuk, J Zhang, LJ Cadang, L Dai US Patent App. 18/526,020, 2024 | | 2024 |
Probing the Protein–Excipient Interaction in the Orally Delivered Protein by Solid-State Hydrogen–Deuterium Exchange Mass Spectrometry and Molecular Dynamics X Pan, S Lenka, J Davis, K Nagapudi, P Mantik, M Saggu, L Dai, ... Analytical Chemistry 96 (2), 802-809, 2023 | | 2023 |
A Highly Efficient Workflow for Detecting and Identifying Sequence Variants in Therapeutic Proteins with a High Resolution LC-MS/MS Method L Cadang, CYJ Tam, BN Moore, J Fichtl, F Yang Molecules 28 (8), 3392, 2023 | | 2023 |
Compositions and methods for stabilizing protein-containing formulations YT Adem, LJ Cadang US Patent App. 17/490,877, 2022 | | 2022 |