The development and application of a single-cell biosensor for the detection of l-methionine and branched-chain amino acids N Mustafi, A Grünberger, D Kohlheyer, M Bott, J Frunzke Metabolic engineering 14 (4), 449-457, 2012 | 254 | 2012 |
Single-cell microfluidics: opportunity for bioprocess development A Grünberger, W Wiechert, D Kohlheyer Current opinion in biotechnology 29, 15-23, 2014 | 192 | 2014 |
Construction of a prophage-free variant of Corynebacterium glutamicum ATCC 13032 for use as a platform strain for basic research and industrial biotechnology M Baumgart, S Unthan, C Rückert, J Sivalingam, A Grünberger, ... Applied and environmental microbiology 79 (19), 6006-6015, 2013 | 180 | 2013 |
Taking control over control: use of product sensing in single cells to remove flux control at key enzymes in biosynthesis pathways G Schendzielorz, M Dippong, A Grunberger, D Kohlheyer, A Yoshida, ... ACS synthetic biology 3 (1), 21-29, 2014 | 167 | 2014 |
A disposable picolitre bioreactor for cultivation and investigation of industrially relevant bacteria on the single cell level A Grünberger, N Paczia, C Probst, G Schendzielorz, L Eggeling, S Noack, ... Lab on a Chip 12 (11), 2060-2068, 2012 | 134 | 2012 |
Beyond growth rate 0.6: What drives Corynebacterium glutamicum to higher growth rates in defined medium S Unthan, A Grünberger, J van Ooyen, J Gätgens, J Heinrich, N Paczia, ... Biotechnology and bioengineering 111 (2), 359-371, 2014 | 131 | 2014 |
Application of a genetically encoded biosensor for live cell imaging of L-valine production in pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum strains N Mustafi, A Grünberger, R Mahr, S Helfrich, K Nöh, B Blombach, ... PloS one 9 (1), e85731, 2014 | 127 | 2014 |
Homogenizing bacterial cell factories: analysis and engineering of phenotypic heterogeneity D Binder, T Drepper, KE Jaeger, F Delvigne, W Wiechert, D Kohlheyer, ... Metabolic engineering 42, 145-156, 2017 | 113 | 2017 |
Spatiotemporal microbial single‐cell analysis using a high‐throughput microfluidics cultivation platform A Grünberger, C Probst, S Helfrich, A Nanda, B Stute, W Wiechert, ... Cytometry Part A 87 (12), 1101-1115, 2015 | 105 | 2015 |
A microfluidic co-cultivation platform to investigate microbial interactions at defined microenvironments A Burmeister, F Hilgers, A Langner, C Westerwalbesloh, Y Kerkhoff, ... Lab on a Chip 19 (1), 98-110, 2019 | 97 | 2019 |
Enhanced protein and biochemical production using CRISPRi-based growth switches S Li, CB Jendresen, A Grünberger, C Ronda, SI Jensen, S Noack, ... Metabolic engineering 38, 274-284, 2016 | 94 | 2016 |
Microfluidics for biotechnology: bridging gaps to foster microfluidic applications V Ortseifen, M Viefhues, L Wobbe, A Grünberger Frontiers in Bioengineering and Biotechnology 8, 589074, 2020 | 86 | 2020 |
Microfluidic picoliter bioreactor for microbial single-cell analysis: fabrication, system setup, and operation A Gruenberger, C Probst, A Heyer, W Wiechert, J Frunzke, D Kohlheyer JoVE (Journal of Visualized Experiments), e50560, 2013 | 83 | 2013 |
Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments A Grünberger, J van Ooyen, N Paczia, P Rohe, G Schiendzielorz, ... Biotechnology and bioengineering 110 (1), 220-228, 2013 | 83 | 2013 |
Engineering and application of a biosensor with focused ligand specificity D Della Corte, HL van Beek, F Syberg, M Schallmey, F Tobola, ... Nature communications 11 (1), 4851, 2020 | 82 | 2020 |
Analysis of SOS-induced spontaneous prophage induction in Corynebacterium glutamicum at the single-cell level AM Nanda, A Heyer, C Krämer, A Grünberger, D Kohlheyer, J Frunzke Journal of bacteriology 196 (1), 180-188, 2014 | 82 | 2014 |
Microfluidic cultivation and analysis tools for interaction studies of microbial co-cultures A Burmeister, A Grünberger Current opinion in biotechnology 62, 106-115, 2020 | 73 | 2020 |
Coarse-grained modeling of protein second osmotic virial coefficients: sterics and short-ranged attractions A Grünberger, PK Lai, MA Blanco, CJ Roberts The Journal of Physical Chemistry B 117 (3), 763-770, 2013 | 68 | 2013 |
Light-responsive control of bacterial gene expression: precise triggering of the lac promoter activity using photocaged IPTG D Binder, A Grünberger, A Loeschcke, C Probst, C Bier, J Pietruszka, ... Integrative biology 6 (8), 755-765, 2014 | 61 | 2014 |
Microfluidic growth chambers with optical tweezers for full spatial single-cell control and analysis of evolving microbes C Probst, A Grünberger, W Wiechert, D Kohlheyer Journal of microbiological methods 95 (3), 470-476, 2013 | 61 | 2013 |