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Synthesis and pharmacology of a novel μ–δ opioid receptor heteromer-selective agonist based on the carfentanyl template A Faouzi, R Uprety, I Gomes, N Massaly, AI Keresztes, V Le Rouzic, ... Journal of medicinal chemistry 63 (22), 13618-13637, 2020 | 30 | 2020 |
A truncated six transmembrane splice variant MOR-1G enhances expression of the full-length seven transmembrane μ-opioid receptor through heterodimerization T Zhang, J Xu, YX Pan Molecular pharmacology 98 (4), 518-527, 2020 | 18 | 2020 |
Binding preference at the μ-opioid receptor underlies distinct pharmacology of cyclopropyl versus valeryl analogs of fentanyl B Xie, VP Le Rouzic, A Goldberg, MHM Tsai, L Chen, T Zhang, A Sinha, ... Neuropharmacology 227, 109442, 2023 | 12 | 2023 |
Photo‐affinity and Metabolic Labeling Probes Based on the Opioid Alkaloids MAL Duque, N Vallavoju, T Zhang, R Yvon, YX Pan, CM Woo ChemBioChem 25 (6), e202300841, 2024 | 2 | 2024 |
Protein State‐Dependent Chemical Biology KA Scott, TL Zhang, SY Xi, B Ngo, EV Vinogradova Israel Journal of Chemistry 63 (3-4), e202200101, 2023 | 2 | 2023 |
Design of first in class bitopic ligands targeting the sodium binding pocket in opioid receptors A Faouzi, S Zaidi, T Che, C Kormos, T Zhang, M Madasu, S Eans, ... The FASEB Journal 34 (S1), 1-1, 2020 | 2 | 2020 |
Covalent targeting of splicing in T cells KA Scott, H Kojima, N Ropek, CD Warren, TL Zhang, SJ Hogg, H Sanford, ... Cell Chemical Biology 32 (1), 201-218. e17, 2025 | 1 | 2025 |
Targeting Exon 7-associated 7TM C-Terminal Variants of the Mu Opioid Receptor Gene for Mitigating Adverse Effects of Mu Opioids Without Altering Analgesia in Pain Management Y Pan, S Liu, R Chien, A Malik, T Zhang, VP Le Rouzic, J Xu, G Rossi, ... Journal of Pharmacology and Experimental Therapeutics 389 (S3), 2024 | | 2024 |
Impact of Oprm1 Exon 1-Associated Alternatively Spliced Variants on Fentanyl-Induced Respiratory Depression A Malik, R Chien, S Liu, J Xu, T Zhang, VP Le Rouzic, M Yosaka, ... Journal of Pharmacology and Experimental Therapeutics 389 (S3), 2024 | | 2024 |
Enhanced expression of the full‐length seven transmembrane mu opioid receptor by MOR‐1G, a truncated six transmembrane splice variants through heterodimerization T Zhang, J Xu, YX Pan The FASEB Journal 34 (S1), 1-1, 2020 | | 2020 |