关注
Mohamed Tawfik Mohamed Nemr
Mohamed Tawfik Mohamed Nemr
Associate professor of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University
在 pharma.cu.edu.eg 的电子邮件经过验证
标题
引用次数
引用次数
年份
Design, synthesis and mechanistic study of new benzenesulfonamide derivatives as anticancer and antimicrobial agents via carbonic anhydrase IX inhibition
MTM Nemr, AM AboulMagd, HM Hassan, AA Hamed, MIA Hamed, ...
RSC advances 11 (42), 26241-26257, 2021
552021
New fused pyrimidine derivatives with anticancer activity: synthesis, topoisomerase II inhibition, apoptotic inducing activity and molecular modeling study
MTM Nemr, AM AboulMagd
Bioorganic Chemistry 103, 104134, 2020
482020
Design, synthesis and biological evaluation of new 2-aminothiazole scaffolds as phosphodiesterase type 5 regulators and COX-1/COX-2 inhibitors
AHM Hussein, AA Khames, ABA El-Adasy, AA Atalla, M Abdel-Rady, ...
RSC advances 10 (50), 29723-29736, 2020
382020
Design, synthesis and antiproliferative evaluation of new tricyclic fused thiazolopyrimidines targeting topoisomerase II: Molecular docking and apoptosis inducing activity
MTM Nemr, A Sonousi, AA Marzouk
Bioorganic Chemistry 105, 104446, 2020
322020
Design, synthesis, modeling studies and biological evaluation of pyrazole derivatives linked to oxime and nitrate moieties as nitric oxide donor selective COX-2 and aromatase …
WAA Fadaly, YAMM Elshaier, MTM Nemr, KRA Abdellatif
Bioorganic Chemistry 134, 106428, 2023
212023
Design, synthesis and chemoinformatic studies of new thiazolopyrimidine derivatives as potent anticancer agents via phosphodiesterase-5 inhibition and apoptotic inducing activity
MTM Nemr, M Teleb, AM AboulMagd, ME El-Naggar, N Gouda, ...
Journal of Molecular Structure 1272, 134216, 2023
182023
Chemistry of 2-vinylindoles: Synthesis and applications
YAAM Elshaier, MTM Nemr, MS Refaey, WAA Fadaly, A Barakat
New Journal of Chemistry 46 (28), 13383-13400, 2022
172022
New pyrazolyl-thiazolidinone/thiazole derivatives as celecoxib/dasatinib analogues with selective COX-2, HER-2 and EGFR inhibitory effects: design, synthesis, anti-inflammatory …
WAA Fadaly, TH Zidan, NM Kahk, FEA Mohamed, MM Abdelhakeem, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2281262, 2023
162023
New 1,2,3-triazole/1,2,4-triazole hybrids linked to oxime moiety as nitric oxide donor selective COX-2, aromatase, B-RAFV600E and EGFR inhibitors celecoxib …
WAA Fadaly, MTM Nemr, TH Zidan, FEA Mohamed, MM Abdelhakeem, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2290461, 2023
142023
Interaction of small molecules with polynucleotide repeats and frameshift site RNA
MTM Nemr, MNM Yousif, J Barciszewski
Archiv Der Pharmazie 352 (8), 1900062, 2019
142019
Discovery of novel pyrazole based Urea/Thiourea derivatives as multiple targeting VEGFR-2, EGFRWT, EGFRT790M tyrosine kinases and COX-2 Inhibitors, with anti-cancer and anti …
WAA Fadaly, MTM Nemr, NM Kahk
Bioorganic Chemistry 147, 107403, 2024
132024
Novel guanidine derivatives targeting leukemia as selective Src/Abl dual inhibitors: Design, synthesis and anti-proliferative activity
AH Moustafa, AM AboulMagd, AM Ali, A Khodairy, AA Marzouk, A Nafady, ...
Bioorganic Chemistry 147, 107410, 2024
112024
Design, synthesis, antineoplastic activity of new pyrazolo [3, 4-d] pyrimidine derivatives as dual CDK2/GSK3β kinase inhibitors; molecular docking study, and ADME prediction
MTM Nemr, A Elshewy, ML Ibrahim, AM El Kerdawy, PA Halim
Bioorganic Chemistry 150, 107566, 2024
92024
Design, synthesis and cytotoxic evaluation of new thieno [2, 3-d] pyrimidine analogues as VEGFR-2/AKT dual inhibitors, apoptosis and autophagy inducers
HK Abd El-Mawgoud, AM AboulMagd, MTM Nemr, MM Hemdan, ...
Bioorganic Chemistry 150, 107622, 2024
72024
Vicinal diaryl pyrazole with tetrazole/urea scaffolds as selective angiotensin converting enzyme‐1/cyclooxygenase‐2 inhibitors: Design, synthesis, anti‐hypertensive, anti …
WAA Fadaly, YAMM Elshaier, FEM Ali, AH El‐Bahrawy, KRA Abdellatif, ...
Drug Development Research 85 (4), e22217, 2024
62024
Novel benzenesulfonamide derivatives as potential selective carbonic anhydrase IX, XII inhibitors with anti-proliferative activity: Design, synthesis and in silico studies
WAA Fadaly, FEA Mohamed, MTM Nemr, AM Sayed, RG Khalil, TH Zidan
Bioorganic Chemistry 153, 107881, 2024
22024
Discovery of novel thiazole derivatives containing pyrazole scaffold as PPAR-γ Agonists, α-Glucosidase, α-Amylase and COX-2 inhibitors; Design, synthesis and in silico study
WAA Fadaly, A Elshewy, MTM Nemr, K Abdou, AM Sayed, NM Kahk
Bioorganic Chemistry 152, 107760, 2024
22024
Application of resin-bound reagents for the synthesis of benzimidazole derivatives
MM Ismail, HM Refaat, MM Kamel, MTM Nemr
Journal of Chemical Research 40 (8), 478-485, 2016
12016
An overview on pharmaceutical applications of phosphodiesterase enzyme 5 (PDE5) inhibitors
M Nemr, MA Abdelaziz, M Teleb, AE Elmasry, YAAM Elshaier
Molecular Diversity, 1-21, 2024
2024
系统目前无法执行此操作,请稍后再试。
文章 1–19