Design, synthesis and mechanistic study of new benzenesulfonamide derivatives as anticancer and antimicrobial agents via carbonic anhydrase IX inhibition MTM Nemr, AM AboulMagd, HM Hassan, AA Hamed, MIA Hamed, ... RSC advances 11 (42), 26241-26257, 2021 | 55 | 2021 |
New fused pyrimidine derivatives with anticancer activity: synthesis, topoisomerase II inhibition, apoptotic inducing activity and molecular modeling study MTM Nemr, AM AboulMagd Bioorganic Chemistry 103, 104134, 2020 | 48 | 2020 |
Design, synthesis and biological evaluation of new 2-aminothiazole scaffolds as phosphodiesterase type 5 regulators and COX-1/COX-2 inhibitors AHM Hussein, AA Khames, ABA El-Adasy, AA Atalla, M Abdel-Rady, ... RSC advances 10 (50), 29723-29736, 2020 | 38 | 2020 |
Design, synthesis and antiproliferative evaluation of new tricyclic fused thiazolopyrimidines targeting topoisomerase II: Molecular docking and apoptosis inducing activity MTM Nemr, A Sonousi, AA Marzouk Bioorganic Chemistry 105, 104446, 2020 | 32 | 2020 |
Design, synthesis, modeling studies and biological evaluation of pyrazole derivatives linked to oxime and nitrate moieties as nitric oxide donor selective COX-2 and aromatase … WAA Fadaly, YAMM Elshaier, MTM Nemr, KRA Abdellatif Bioorganic Chemistry 134, 106428, 2023 | 21 | 2023 |
Design, synthesis and chemoinformatic studies of new thiazolopyrimidine derivatives as potent anticancer agents via phosphodiesterase-5 inhibition and apoptotic inducing activity MTM Nemr, M Teleb, AM AboulMagd, ME El-Naggar, N Gouda, ... Journal of Molecular Structure 1272, 134216, 2023 | 18 | 2023 |
Chemistry of 2-vinylindoles: Synthesis and applications YAAM Elshaier, MTM Nemr, MS Refaey, WAA Fadaly, A Barakat New Journal of Chemistry 46 (28), 13383-13400, 2022 | 17 | 2022 |
New pyrazolyl-thiazolidinone/thiazole derivatives as celecoxib/dasatinib analogues with selective COX-2, HER-2 and EGFR inhibitory effects: design, synthesis, anti-inflammatory … WAA Fadaly, TH Zidan, NM Kahk, FEA Mohamed, MM Abdelhakeem, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2281262, 2023 | 16 | 2023 |
New 1,2,3-triazole/1,2,4-triazole hybrids linked to oxime moiety as nitric oxide donor selective COX-2, aromatase, B-RAFV600E and EGFR inhibitors celecoxib … WAA Fadaly, MTM Nemr, TH Zidan, FEA Mohamed, MM Abdelhakeem, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2290461, 2023 | 14 | 2023 |
Interaction of small molecules with polynucleotide repeats and frameshift site RNA MTM Nemr, MNM Yousif, J Barciszewski Archiv Der Pharmazie 352 (8), 1900062, 2019 | 14 | 2019 |
Discovery of novel pyrazole based Urea/Thiourea derivatives as multiple targeting VEGFR-2, EGFRWT, EGFRT790M tyrosine kinases and COX-2 Inhibitors, with anti-cancer and anti … WAA Fadaly, MTM Nemr, NM Kahk Bioorganic Chemistry 147, 107403, 2024 | 13 | 2024 |
Novel guanidine derivatives targeting leukemia as selective Src/Abl dual inhibitors: Design, synthesis and anti-proliferative activity AH Moustafa, AM AboulMagd, AM Ali, A Khodairy, AA Marzouk, A Nafady, ... Bioorganic Chemistry 147, 107410, 2024 | 11 | 2024 |
Design, synthesis, antineoplastic activity of new pyrazolo [3, 4-d] pyrimidine derivatives as dual CDK2/GSK3β kinase inhibitors; molecular docking study, and ADME prediction MTM Nemr, A Elshewy, ML Ibrahim, AM El Kerdawy, PA Halim Bioorganic Chemistry 150, 107566, 2024 | 9 | 2024 |
Design, synthesis and cytotoxic evaluation of new thieno [2, 3-d] pyrimidine analogues as VEGFR-2/AKT dual inhibitors, apoptosis and autophagy inducers HK Abd El-Mawgoud, AM AboulMagd, MTM Nemr, MM Hemdan, ... Bioorganic Chemistry 150, 107622, 2024 | 7 | 2024 |
Vicinal diaryl pyrazole with tetrazole/urea scaffolds as selective angiotensin converting enzyme‐1/cyclooxygenase‐2 inhibitors: Design, synthesis, anti‐hypertensive, anti … WAA Fadaly, YAMM Elshaier, FEM Ali, AH El‐Bahrawy, KRA Abdellatif, ... Drug Development Research 85 (4), e22217, 2024 | 6 | 2024 |
Novel benzenesulfonamide derivatives as potential selective carbonic anhydrase IX, XII inhibitors with anti-proliferative activity: Design, synthesis and in silico studies WAA Fadaly, FEA Mohamed, MTM Nemr, AM Sayed, RG Khalil, TH Zidan Bioorganic Chemistry 153, 107881, 2024 | 2 | 2024 |
Discovery of novel thiazole derivatives containing pyrazole scaffold as PPAR-γ Agonists, α-Glucosidase, α-Amylase and COX-2 inhibitors; Design, synthesis and in silico study WAA Fadaly, A Elshewy, MTM Nemr, K Abdou, AM Sayed, NM Kahk Bioorganic Chemistry 152, 107760, 2024 | 2 | 2024 |
Application of resin-bound reagents for the synthesis of benzimidazole derivatives MM Ismail, HM Refaat, MM Kamel, MTM Nemr Journal of Chemical Research 40 (8), 478-485, 2016 | 1 | 2016 |
An overview on pharmaceutical applications of phosphodiesterase enzyme 5 (PDE5) inhibitors M Nemr, MA Abdelaziz, M Teleb, AE Elmasry, YAAM Elshaier Molecular Diversity, 1-21, 2024 | | 2024 |