The changing epidemiology of autism spectrum disorders K Lyall, L Croen, J Daniels, MD Fallin, C Ladd-Acosta, BK Lee, BY Park, ... Annual review of public health 38 (1), 81-102, 2017 | 1125 | 2017 |
Distinct signaling of coreceptors regulates specific metabolism pathways and impacts memory development in CAR T cells OU Kawalekar, RS O’Connor, JA Fraietta, L Guo, SE McGettigan, ... Immunity 44 (2), 380-390, 2016 | 1116 | 2016 |
Evidence for intramyocardial disruption of lipid metabolism and increased myocardial ketone utilization in advanced human heart failure KC Bedi Jr, NW Snyder, J Brandimarto, M Aziz, C Mesaros, AJ Worth, ... Circulation 133 (8), 706-716, 2016 | 557 | 2016 |
Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation JV Lee, A Carrer, S Shah, NW Snyder, S Wei, S Venneti, AJ Worth, ... Cell metabolism 20 (2), 306-319, 2014 | 555 | 2014 |
Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate S Zhao, C Jang, J Liu, K Uehara, M Gilbert, L Izzo, X Zeng, S Trefely, ... Nature 579 (7800), 586-591, 2020 | 375 | 2020 |
Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation AJ Covarrubias, HI Aksoylar, J Yu, NW Snyder, AJ Worth, SS Iyer, J Wang, ... elife 5, e11612, 2016 | 375 | 2016 |
ATP-citrate lyase controls a glucose-to-acetate metabolic switch S Zhao, AM Torres, RA Henry, S Trefely, M Wallace, JV Lee, A Carrer, ... Cell reports 17 (4), 1037-1052, 2016 | 356 | 2016 |
Acetyl-CoA metabolism supports multistep pancreatic tumorigenesis A Carrer, S Trefely, S Zhao, SL Campbell, RJ Norgard, KC Schultz, ... Cancer discovery 9 (3), 416-435, 2019 | 239 | 2019 |
Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47− mediated ‘don’t-eat-me’signal M Liu, RS O’Connor, S Trefely, K Graham, NW Snyder, GL Beatty Nature immunology 20 (3), 265-275, 2019 | 214 | 2019 |
Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response M Uribe-Herranz, S Rafail, S Beghi, L Gil-de-Gómez, I Verginadis, ... The Journal of clinical investigation 130 (1), 466-479, 2020 | 207 | 2020 |
Characterization of histone acylations links chromatin modifications with metabolism J Simithy, S Sidoli, ZF Yuan, M Coradin, NV Bhanu, DM Marchione, ... Nature communications 8 (1), 1141, 2017 | 183 | 2017 |
Compartmentalised acyl-CoA metabolism and roles in chromatin regulation S Trefely, CD Lovell, NW Snyder, KE Wellen Molecular metabolism 38, 100941, 2020 | 175 | 2020 |
A PRDM16-driven metabolic signal from adipocytes regulates precursor cell fate W Wang, J Ishibashi, S Trefely, M Shao, AJ Cowan, A Sakers, HW Lim, ... Cell metabolism 30 (1), 174-189. e5, 2019 | 172 | 2019 |
Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses PK Langston, A Nambu, J Jung, M Shibata, HI Aksoylar, J Lei, P Xu, ... Nature immunology 20 (9), 1186-1195, 2019 | 169 | 2019 |
Impact of a high-fat diet on tissue Acyl-CoA and histone acetylation levels A Carrer, JLD Parris, S Trefely, RA Henry, DC Montgomery, AM Torres, ... Journal of Biological Chemistry 292 (8), 3312-3322, 2017 | 164 | 2017 |
The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations RS O’Connor, L Guo, S Ghassemi, NW Snyder, AJ Worth, L Weng, Y Kam, ... Scientific reports 8 (1), 6289, 2018 | 155 | 2018 |
Safety, pharmacodynamics, and potential benefit of omaveloxolone in Friedreich ataxia DR Lynch, J Farmer, L Hauser, IA Blair, QQ Wang, C Mesaros, N Snyder, ... Annals of clinical and translational neurology 6 (1), 15-26, 2019 | 136 | 2019 |
Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy PK Kopinski, KA Janssen, PM Schaefer, S Trefely, CE Perry, P Potluri, ... Proceedings of the National Academy of Sciences 116 (32), 16028-16035, 2019 | 130 | 2019 |
mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis C Martinez Calejman, S Trefely, SW Entwisle, A Luciano, SM Jung, ... Nature communications 11 (1), 575, 2020 | 120 | 2020 |
Acetyl-CoA promotes glioblastoma cell adhesion and migration through Ca2+–NFAT signaling JV Lee, CT Berry, K Kim, P Sen, T Kim, A Carrer, S Trefely, S Zhao, ... Genes & development 32 (7-8), 497-511, 2018 | 118 | 2018 |