Attenuation of MCP-1/CCL2 expression ameliorates neuropathy in a mouse model for Charcot–Marie–Tooth 1X J Groh, K Heinl, B Kohl, C Wessig, J Greeske, S Fischer, R Martini Human molecular genetics 19 (18), 3530-3543, 2010 | 96 | 2010 |
Targeting the colony stimulating factor 1 receptor alleviates two forms of Charcot–Marie–Tooth disease in mice D Klein, A Patzko, D Schreiber, A van Hauwermeiren, M Baier, J Groh, ... Brain 138 (11), 3193-3205, 2015 | 95 | 2015 |
Colony-stimulating factor-1 mediates macrophage-related neural damage in a model for Charcot–Marie–Tooth disease type 1X J Groh, J Weis, H Zieger, ER Stanley, H Heuer, R Martini Brain 135 (1), 88-104, 2012 | 88 | 2012 |
CD8+ T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging T Kaya, N Mattugini, L Liu, H Ji, L Cantuti-Castelvetri, J Wu, M Schifferer, ... Nature neuroscience 25 (11), 1446-1457, 2022 | 81 | 2022 |
MCP-1/CCL2 modifies axon properties in a PMP22-overexpressing mouse model for Charcot-Marie-tooth 1A neuropathy B Kohl, S Fischer, J Groh, C Wessig, R Martini The American journal of pathology 176 (3), 1390-1399, 2010 | 77 | 2010 |
Nonuniform molecular features of myelinating Schwann cells in models for CMT1: Distinct disease patterns are associated with NCAM and c‐Jun upregulation D Klein, J Groh, J Wettmarshausen, R Martini Glia 62 (5), 736-750, 2014 | 67 | 2014 |
Immune cells perturb axons and impair neuronal survival in a mouse model of infantile neuronal ceroid lipofuscinosis J Groh, TG Kühl, CW Ip, HR Nelvagal, S Sri, S Duckett, M Mirza, ... Brain 136 (4), 1083-1101, 2013 | 66 | 2013 |
Similarities between inherited demyelinating neuropathies and Wallerian degeneration: an old repair program may cause myelin and axon perturbation under nonlesion conditions R Martini, D Klein, J Groh The American journal of pathology 183 (3), 655-660, 2013 | 61 | 2013 |
CSF‐1‐activated macrophages are target‐directed and essential mediators of schwann cell dedifferentiation and dysfunction in C x32‐deficient mice J Groh, I Klein, C Hollmann, J Wettmarshausen, D Klein, R Martini Glia 63 (6), 977-986, 2015 | 60 | 2015 |
Fingolimod and teriflunomide attenuate neurodegeneration in mouse models of neuronal ceroid lipofuscinosis J Groh, K Berve, R Martini Molecular Therapy 25 (8), 1889-1899, 2017 | 59 | 2017 |
The CLN3 gene and protein: What we know M Mirza, A Vainshtein, A DiRonza, U Chandrachud, LJ Haslett, M Palmieri, ... Molecular genetics & genomic medicine 7 (12), e859, 2019 | 56 | 2019 |
Sialoadhesin promotes neuroinflammation‐related disease progression in two mouse models of CLN disease J Groh, E Ribechini, D Stadler, T Schilling, MB Lutz, R Martini Glia 64 (5), 792-809, 2016 | 54 | 2016 |
Accumulation of cytotoxic T cells in the aged CNS leads to axon degeneration and contributes to cognitive and motor decline J Groh, K Knöpper, P Arampatzi, X Yuan, L Lößlein, AE Saliba, ... Nature Aging 1 (4), 357-367, 2021 | 51 | 2021 |
Neuroinflammation by cytotoxic T-lymphocytes impairs retrograde axonal transport in an oligodendrocyte mutant mouse CW Ip, A Kroner, J Groh, M Huber, D Klein, I Spahn, R Diem, SK Williams, ... Public Library of Science 7 (8), e42554, 2012 | 41 | 2012 |
Non-invasive assessment of retinal alterations in mouse models of infantile and juvenile neuronal ceroid lipofuscinosis by spectral domain optical coherence tomography J Groh, D Stadler, M Buttmann, R Martini Acta neuropathologica communications 2, 1-12, 2014 | 40 | 2014 |
Tor1a+/- mice develop dystonia-like movements via a striatal dopaminergic dysregulation triggered by peripheral nerve injury CW Ip, IU Isaias, BB Kusche-Tekin, D Klein, J Groh, A O’Leary, S Knorr, ... Acta neuropathologica communications 4, 1-14, 2016 | 37 | 2016 |
Pathogenic inflammation in the CNS of mice carrying human PLP1 mutations J Groh, HC Friedman, N Orel, CW Ip, S Fischer, I Spahn, E Schäffner, ... Human molecular genetics 25 (21), 4686-4702, 2016 | 35 | 2016 |
Neuroinflammation as modifier of genetically caused neurological disorders of the central nervous system: understanding pathogenesis and chances for treatment J Groh, R Martini Glia 65 (9), 1407-1422, 2017 | 34 | 2017 |
Targeting microglia attenuates neuroinflammation‐related neural damage in mice carrying human PLP1 mutations J Groh, D Klein, K Berve, BL West, R Martini Glia 67 (2), 277-290, 2019 | 33 | 2019 |
Cell-surface and secreted isoforms of CSF-1 exert opposing roles in macrophage-mediated neural damage in Cx32-deficient mice J Groh, R Basu, ER Stanley, R Martini Journal of Neuroscience 36 (6), 1890-1901, 2016 | 29 | 2016 |