The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn–/– mice and results in a mouse with spinal muscular atrophy UR Monani, M Sendtner, DD Coovert, DW Parsons, C Andreassi, TT Le, ... Human molecular genetics 9 (3), 333-339, 2000 | 891 | 2000 |
RETRACTED ARTICLE: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN KD Foust, X Wang, VL McGovern, L Braun, AK Bevan, AM Haidet, TT Le, ... Nature biotechnology 28 (3), 271-274, 2010 | 871 | 2010 |
The survival motor neuron protein in spinal muscular atrophy DD Coovert, TT Le, PE McAndrew, J Strasswimmer, TO Crawford, ... Human molecular genetics 6 (8), 1205-1214, 1997 | 862 | 1997 |
SMNΔ7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full … TT Le, LT Pham, MER Butchbach, HL Zhang, UR Monani, DD Coovert, ... Human molecular genetics 14 (6), 845-857, 2005 | 702 | 2005 |
SMN oligomerization defect correlates with spinal muscular atrophy severity CL Lorson, J Strasswimmer, JM Yao, JD Baleja, E Hahnen, B Wirth, T Le, ... Nature genetics 19 (1), 63-66, 1998 | 629 | 1998 |
Lentivector-mediated SMN replacement in a mouse model of spinal muscular atrophy M Azzouz, T Le, GS Ralph, L Walmsley, UR Monani, DCP Lee, F Wilkes, ... The Journal of clinical investigation 114 (12), 1726-1731, 2004 | 259 | 2004 |
The relationship between SMN, the spinal muscular atrophy protein, and nuclear coiled bodies in differentiated tissues and cultured cells PJ Young, TT Le, N thi Man, AHM Burghes, GE Morris Experimental cell research 256 (2), 365-374, 2000 | 189 | 2000 |
A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy UR Monani, MT Pastore, TO Gavrilina, S Jablonka, TT Le, C Andreassi, ... The Journal of cell biology 160 (1), 41-52, 2003 | 174 | 2003 |
Nuclear gems and Cajal (coiled) bodies in fetal tissues: nucleolar distribution of the spinal muscular atrophy protein, SMN PJ Young, TT Le, M Dunckley, N thi Man, AHM Burghes, GE Morris Experimental cell research 265 (2), 252-261, 2001 | 170 | 2001 |
In vivo targeted repair of a point mutation in the canine dystrophin gene by a chimeric RNA/DNA oligonucleotide RJ Bartlett, S Stockinger, MM Denis, WT Bartlett, L Inverardi, TT Le, ... Nature biotechnology 18 (6), 615-622, 2000 | 170 | 2000 |
A role for complexes of survival of motor neurons (SMN) protein with gemins and profilin in neurite-like cytoplasmic extensions of cultured nerve cells A Sharma, A Lambrechts, TT Le, CA Sewry, C Ampe, AHM Burghes, ... Experimental cell research 309 (1), 185-197, 2005 | 157 | 2005 |
Assessing the roles that absorptive capacity and economic distance play in the foreign direct investment-productivity growth nexus P Bodman, T Le Applied Economics 45 (8), 1027-1039, 2013 | 153 | 2013 |
Temporal requirement for high SMN expression in SMA mice TT Le, VL McGovern, IE Alwine, X Wang, A Massoni-Laporte, MM Rich, ... Human molecular genetics 20 (18), 3578-3591, 2011 | 148 | 2011 |
The exon 2b region of the spinal muscular atrophy protein, SMN, is involved in self-association and SIP1 binding PJ Young, N Man, CL Lorson, TT Le, EJ Androphy, AHM Burghes, ... Human molecular genetics 9 (19), 2869-2877, 2000 | 132 | 2000 |
‘Brain drain’or ‘brain circulation’: Evidence from OECD's international migration and R&D spillovers T Le Scottish Journal of Political Economy 55 (5), 618-636, 2008 | 112 | 2008 |
Trade, remittances, institutions, and economic growth T Le International Economic Journal 23 (3), 391-408, 2009 | 107 | 2009 |
Remittances for economic development: The investment perspective T Le Economic Modelling 28 (6), 2409-2415, 2011 | 66 | 2011 |
Plastin 3 expression does not modify spinal muscular atrophy severity in the∆ 7 SMA mouse VL McGovern, A Massoni-Laporte, X Wang, TT Le, HT Le, CE Beattie, ... PloS one 10 (7), e0132364, 2015 | 58 | 2015 |
Connectedness between nonrenewable and renewable energy consumption, economic growth and CO2 emission in Vietnam: New evidence from a wavelet analysis TH Le Renewable Energy 195, 442-454, 2022 | 57 | 2022 |
Are student flows a significant channel of R&D spillovers from the north to the south? T Le Economics Letters 107 (3), 315-317, 2010 | 56 | 2010 |