| 8-oxo-guanine bypass by human DNA polymerases in the presence of auxiliary proteins G Maga, G Villani, E Crespan, U Wimmer, E Ferrari, B Bertocci, ... Nature 447 (7144), 606-608, 2007 | 265 | 2007 |
| Structure-Based Optimization of Pyrazolo[3,4-d]pyrimidines as Abl Inhibitors and Antiproliferative Agents toward Human Leukemia Cell Lines F Manetti, C Brullo, M Magnani, F Mosci, B Chelli, E Crespan, ... Journal of medicinal chemistry 51 (5), 1252-1259, 2008 | 99 | 2008 |
| Design, Synthesis, Biological Activity, and ADME Properties of Pyrazolo[3,4-d]pyrimidines Active in Hypoxic Human Leukemia Cells: A Lead Optimization Study M Radi, E Dreassi, C Brullo, E Crespan, C Tintori, V Bernardo, M Valoti, ... Journal of medicinal chemistry 54 (8), 2610-2626, 2011 | 97 | 2011 |
| Synthesis, biological evaluation and docking studies of 4-amino substituted 1H-pyrazolo [3, 4-d] pyrimidines S Schenone, C Brullo, O Bruno, F Bondavalli, L Mosti, G Maga, E Crespan, ... European journal of medicinal chemistry 43 (12), 2665-2676, 2008 | 92 | 2008 |
| Combining X-ray Crystallography and Molecular Modeling toward the Optimization of Pyrazolo[3,4-d]pyrimidines as Potent c-Src Inhibitors Active in Vivo against … C Tintori, AL Fallacara, M Radi, C Zamperini, E Dreassi, E Crespan, ... Journal of Medicinal Chemistry 58 (1), 347-361, 2015 | 81 | 2015 |
| Replication protein A and proliferating cell nuclear antigen coordinate DNA polymerase selection in 8-oxo-guanine repair G Maga, E Crespan, U Wimmer, B van Loon, A Amoroso, C Mondello, ... Proceedings of the National Academy of Sciences 105 (52), 20689-20694, 2008 | 80 | 2008 |
| Discovery and SAR of 1, 3, 4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents M Radi, E Crespan, G Botta, F Falchi, G Maga, F Manetti, V Corradi, ... Bioorganic & medicinal chemistry letters 18 (3), 1207-1211, 2008 | 79 | 2008 |
| Parallel solution-phase and microwave-assisted synthesis of new S-DABO derivatives endowed with subnanomolar anti-HIV-1 activity F Manetti, JA Esté, I Clotet-Codina, M Armand-Ugón, G Maga, E Crespan, ... Journal of medicinal chemistry 48 (25), 8000-8008, 2005 | 72 | 2005 |
| Microhomology-mediated DNA strand annealing and elongation by human DNA polymerases λ and β on normal and repetitive DNA sequences E Crespan, T Czabany, G Maga, U Hübscher Nucleic acids research 40 (12), 5577-5590, 2012 | 69 | 2012 |
| Oxidative DNA Damage Bypass in Arabidopsis thaliana Requires DNA Polymerase λ and Proliferating Cell Nuclear Antigen 2 A Amoroso, L Concia, C Maggio, C Raynaud, C Bergounioux, E Crespan, ... The Plant Cell 23 (2), 806-822, 2011 | 69 | 2011 |
| Novel 1-[2-(Diarylmethoxy) ethyl]-2-methyl-5-nitroimidazoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. A structure− activity relationship investigation G De Martino, G La Regina, A Di Pasquali, R Ragno, A Bergamini, ... Journal of medicinal chemistry 48 (13), 4378-4388, 2005 | 69 | 2005 |
| Indolyl-pyrrolone as a new scaffold for Pim1 inhibitors S Olla, F Manetti, E Crespan, G Maga, A Angelucci, S Schenone, ... Bioorganic & Medicinal Chemistry Letters 19 (5), 1512-1516, 2009 | 62 | 2009 |
| Discovery of multitarget antivirals acting on both the Dengue virus NS5-NS3 interaction and the host Src/Fyn kinases P Vincetti, F Caporuscio, S Kaptein, A Gioiello, V Mancino, Y Suzuki, ... Journal of medicinal chemistry 58 (12), 4964-4975, 2015 | 61 | 2015 |
| N‐[2‐Methyl‐5‐(triazol‐1‐yl)phenyl]pyrimidin‐2‐amine as a Scaffold for the Synthesis of Inhibitors of Bcr‐Abl F Arioli, S Borrelli, F Colombo, F Falchi, I Filippi, E Crespan, A Naldini, ... ChemMedChem 6 (11), 2009-2018, 2011 | 59 | 2011 |
| DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7, 8-dihydroguanine bypass G Maga, E Crespan, E Markkanen, R Imhof, A Furrer, G Villani, ... Proceedings of the National Academy of Sciences 110 (47), 18850-18855, 2013 | 57 | 2013 |
| Identification of potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cells M Radi, C Brullo, E Crespan, C Tintori, F Musumeci, M Biava, S Schenone, ... Bioorganic & medicinal chemistry letters 21 (19), 5928-5933, 2011 | 55 | 2011 |
| Identification of Hck inhibitors as hits for the development of antileukemia and anti‐HIV agents C Tintori, I Laurenzana, F La Rocca, F Falchi, F Carraro, A Ruiz, JA Esté, ... ChemMedChem 8 (8), 1353-1360, 2013 | 53 | 2013 |
| Design, Synthesis, and Biological Evaluation of Pyrazolo[3,4-d]pyrimidines Active in Vivo on the Bcr-Abl T315I Mutant M Radi, C Tintori, F Musumeci, C Brullo, C Zamperini, E Dreassi, ... Journal of Medicinal Chemistry 56 (13), 5382-5394, 2013 | 52 | 2013 |
| Indolylarylsulfones carrying a heterocyclic tail as very potent and broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitors V Famiglini, G La Regina, A Coluccia, S Pelliccia, A Brancale, G Maga, ... Journal of medicinal chemistry 57 (23), 9945-9957, 2014 | 50 | 2014 |
| Error-free bypass of 2-hydroxyadenine by human DNA polymerase λ with Proliferating Cell Nuclear Antigen and Replication Protein A in different sequence contexts E Crespan, U Hübscher, G Maga Nucleic Acids Research 35 (15), 5173-5181, 2007 | 50 | 2007 |
