The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis NG Bérubé, M Mangelsdorf, M Jagla, J Vanderluit, D Garrick, RJ Gibbons, ... The Journal of clinical investigation 115 (2), 258-267, 2005 | 243 | 2005 |
ATRX partners with cohesin and MeCP2 and contributes to developmental silencing of imprinted genes in the brain KD Kernohan, Y Jiang, DC Tremblay, AC Bonvissuto, JH Eubanks, ... Developmental cell 18 (2), 191-202, 2010 | 202 | 2010 |
Loss of ATRX leads to chromosome cohesion and congression defects K Ritchie, C Seah, J Moulin, C Isaac, F Dick, NG Bérubé The Journal of cell biology 180 (2), 315-324, 2008 | 196 | 2008 |
Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes MJ Bertram, NG Berube, X Hang-Swanson, Q Ran, JK Leung, S Bryce, ... Molecular and cellular biology 19 (2), 1479-1485, 1999 | 184 | 1999 |
Cell cycle-dependent phosphorylation of the ATRX protein correlates with changes in nuclear matrix and chromatin association NG Bérubé, CA Smeenk, DJ Picketts Human molecular genetics 9 (4), 539-547, 2000 | 182 | 2000 |
The retinoblastoma protein regulates pericentric heterochromatin CE Isaac, SM Francis, AL Martens, LM Julian, LA Seifried, N Erdmann, ... Molecular and cellular biology 26 (9), 3659-3671, 2006 | 153 | 2006 |
Epigenetic etiology of intellectual disability S Iwase, NG Bérubé, Z Zhou, NN Kasri, E Battaglioli, M Scandaglia, ... Journal of Neuroscience 37 (45), 10773-10782, 2017 | 148 | 2017 |
Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span LA Watson, LA Solomon, JR Li, Y Jiang, M Edwards, K Shin-Ya, F Beier, ... The Journal of clinical investigation 123 (5), 2049-2063, 2013 | 141 | 2013 |
Mitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressive CH Coschi, AL Martens, K Ritchie, SM Francis, S Chakrabarti, NG Berube, ... Genes & development 24 (13), 1351-1363, 2010 | 140 | 2010 |
Implantation Failure in Female Kiss1−/− Mice Is Independent of Their Hypogonadic State and Can Be Partially Rescued by Leukemia Inhibitory Factor M Calder, YM Chan, R Raj, M Pampillo, A Elbert, M Noonan, ... Endocrinology 155 (8), 3065-3078, 2014 | 96 | 2014 |
ATRX promotes gene expression by facilitating transcriptional elongation through guanine-rich coding regions MA Levy, KD Kernohan, Y Jiang, NG Bérubé Human molecular genetics 24 (7), 1824-1835, 2015 | 91 | 2015 |
Down-Regulation of CD9 Expression during Prostate Carcinoma Progression Is Associated with CD9 mRNA Modifications JC Wang, LR Bégin, NG Bérubé, S Chevalier, AG Aprikian, H Gourdeau, ... Clinical cancer research 13 (8), 2354-2361, 2007 | 90 | 2007 |
Identification of epigenetic signature associated with alpha thalassemia/mental retardation X-linked syndrome LC Schenkel, KD Kernohan, A McBride, D Reina, A Hodge, PJ Ainsworth, ... Epigenetics & chromatin 10, 1-11, 2017 | 85 | 2017 |
Complex Seizure Disorder Caused by Brunol4 Deficiency in Mice Y Yang, CL Mahaffey, N Bérubé, TP Maddatu, GA Cox, WN Frankel PLoS genetics 3 (7), e124, 2007 | 84 | 2007 |
Analysis of neonatal brain lacking ATRX or MeCP2 reveals changes in nucleosome density, CTCF binding and chromatin looping KD Kernohan, D Vernimmen, GB Gloor, NG Bérubé Nucleic acids research 42 (13), 8356-8368, 2014 | 81 | 2014 |
Dual effect of CTCF loss on neuroprogenitor differentiation and survival LA Watson, X Wang, A Elbert, KD Kernohan, N Galjart, NG Bérubé Journal of Neuroscience 34 (8), 2860-2870, 2014 | 81 | 2014 |
Neurodevelopmental defects resulting from ATRX overexpression in transgenic mice NG Bérubé, M Jagla, C Smeenk, Y De Repentigny, R Kothary, DJ Picketts Human molecular genetics 11 (3), 253-261, 2002 | 81 | 2002 |
Emerging roles of ATRX in cancer LA Watson, H Goldberg, NG Bérubé Epigenomics 7 (8), 1365-1378, 2015 | 75 | 2015 |
Transcriptional regulators of chondrocyte hypertrophy LA Solomon, NG Bérubé, F Beier Birth Defects Research Part C: Embryo Today: Reviews 84 (2), 123-130, 2008 | 73 | 2008 |
Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53 C Seah, MA Levy, Y Jiang, S Mokhtarzada, DR Higgs, RJ Gibbons, ... Journal of Neuroscience 28 (47), 12570-12580, 2008 | 72 | 2008 |