The mu-opioid receptor and the NMDA receptor associate in PAG neurons: implications in pain control M Rodríguez-Muñoz, P Sánchez-Blázquez, A Vicente-Sánchez, ... Neuropsychopharmacology 37 (2), 338-349, 2012 | 192 | 2012 |
The cannabinoid receptor 1 associates with NMDA receptors to produce glutamatergic hypofunction: implications in psychosis and schizophrenia P Sánchez-Blázquez, M Rodríguez-Muñoz, J Garzón Frontiers in pharmacology 4, 169, 2014 | 147 | 2014 |
Cannabidiol enhances morphine antinociception, diminishes NMDA-mediated seizures and reduces stroke damage via the sigma 1 receptor M Rodríguez-Muñoz, Y Onetti, E Cortés-Montero, J Garzón, ... Molecular brain 11, 1-12, 2018 | 112 | 2018 |
Activation of μ-opioid receptors transfers control of Gα subunits to the regulator of G-protein signaling RGS9-2: role in receptor desensitization J Garzón, M Rodríguez-Muñoz, A López-Fando, P Sánchez-Blázquez Journal of Biological Chemistry 280 (10), 8951-8960, 2005 | 100 | 2005 |
Endocannabinoid control of glutamate NMDA receptors: the therapeutic potential and consequences of dysfunction M Rodríguez-Muñoz, P Sánchez-Blázquez, M Merlos, J Garzón-Niño Oncotarget 7 (34), 55840, 2016 | 93 | 2016 |
Direct association of Mu-opioid and NMDA glutamate receptors supports their cross-regulation: molecular implications for opioid tolerance J Garzón, M Rodríguez-Muñoz, P Sánchez-Blázquez Current drug abuse reviews 5 (3), 199-226, 2012 | 91 | 2012 |
The σ1 receptor engages the redox-regulated HINT1 protein to bring opioid analgesia under NMDA receptor negative control M Rodríguez-Muñoz, P Sánchez-Blázquez, R Herrero-Labrador, ... Antioxidants & redox signaling 22 (10), 799-818, 2015 | 89 | 2015 |
The RGSZ2 protein exists in a complex with μ-opioid receptors and regulates the desensitizing capacity of Gz proteins J Garzón, M Rodríguez-Muñoz, A López-Fando, P Sánchez-Blázquez Neuropsychopharmacology 30 (9), 1632-1648, 2005 | 89 | 2005 |
Cannabinoid receptors couple to NMDA receptors to reduce the production of NO and the mobilization of zinc induced by glutamate P Sánchez-Blázquez, M Rodríguez-Muñoz, A Vicente-Sánchez, J Garzón Antioxidants & Redox Signaling 19 (15), 1766-1782, 2013 | 82 | 2013 |
Morphine alters the selective association between mu-opioid receptors and specific RGS proteins in mouse periaqueductal gray matter J Garzón, M Rodríguez-Muñoz, P Sánchez-Blázquez Neuropharmacology 48 (6), 853-868, 2005 | 80 | 2005 |
NMDAR-nNOS generated zinc recruits PKCγ to the HINT1–RGS17 complex bound to the C terminus of Mu-opioid receptors M Rodríguez-Muñoz, E de la Torre-Madrid, P Sánchez-Blázquez, ... Cellular signalling 20 (10), 1855-1864, 2008 | 79 | 2008 |
RGSZ1 and GAIP regulate μ-but not δ-opioid receptors in mouse CNS: role in tachyphylaxis and acute tolerance J Garzón, M Rodríguez-Muñoz, A López-Fando, A García-España, ... Neuropsychopharmacology 29 (6), 1091-1104, 2004 | 74 | 2004 |
Mu-opioid receptors transiently activate the Akt-nNOS pathway to produce sustained potentiation of PKC-mediated NMDAR-CaMKII signaling P Sánchez-Blázquez, M Rodriguez-Munoz, J Garzon PloS one 5 (6), e11278, 2010 | 71 | 2010 |
The ON: OFF switch, σ1R-HINT1 protein, controls GPCR-NMDA receptor cross-regulation: implications in neurological disorders M Rodríguez-Muñoz, E Cortés-Montero, A Pozo-Rodrigálvarez, ... Oncotarget 6 (34), 35458, 2015 | 68 | 2015 |
The histidine triad nucleotide-binding protein 1 supports mu-opioid receptor–glutamate NMDA receptor cross-regulation M Rodríguez-Muñoz, P Sánchez-Blázquez, A Vicente-Sánchez, C Bailón, ... Cellular and Molecular Life Sciences 68, 2933-2949, 2011 | 66 | 2011 |
Do pharmacological approaches that prevent opioid tolerance target different elements in the same regulatory machinery? J Garzón, M Rodríguez-Muñoz, P Sánchez-Blázquez Current drug abuse reviews 1 (2), 222-238, 2008 | 64 | 2008 |
Sumoylated RGS-Rz proteins act as scaffolds for Mu-opioid receptors and G-protein complexes in mouse brain M Rodríguez-Muñoz, D Bermúdez, P Sánchez-Blázquez, J Garzón Neuropsychopharmacology 32 (4), 842-850, 2007 | 63 | 2007 |
Gz mediates the long-lasting desensitization of brain CB1 receptors and is essential for cross-tolerance with morphine J Garzón, E de la Torre-Madrid, M Rodríguez-Muñoz, A Vicente-Sánchez, ... Molecular pain 5, 1744-8069-5-11, 2009 | 61 | 2009 |
The calcium-sensitive Sigma-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases P Sánchez-Blázquez, M Rodríguez-Muñoz, R Herrero-Labrador, ... International Journal of Neuropsychopharmacology 17 (12), 1943-1955, 2014 | 59 | 2014 |
HINT1 protein cooperates with cannabinoid 1 receptor to negatively regulate glutamate NMDA receptor activity A Vicente-Sánchez, P Sánchez-Blázquez, M Rodríguez-Muñoz, J Garzón Molecular Brain 6, 1-16, 2013 | 59 | 2013 |