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| Hypoxic tumor microenvironment activates GLI2 via HIF-1α and TGF-β2 to promote chemoresistance in colorectal cancer YA Tang, Y Chen, Y Bao, S Mahara, SMJM Yatim, G Oguz, PL Lee, ... Proceedings of the National Academy of Sciences 115 (26), E5990-E5999, 2018 | 248 | 2018 |
| IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel ZN Wee, SMJM Yatim, VK Kohlbauer, M Feng, JY Goh, Y Bao, PL Lee, ... Nature communications 6 (1), 8746, 2015 | 173 | 2015 |
| PDK1 signaling toward PLK1–MYC activation confers oncogenic transformation, tumor-initiating cell activation, and resistance to mTOR-targeted therapy J Tan, Z Li, PL Lee, P Guan, MY Aau, ST Lee, M Feng, CZ Lim, EYJ Lee, ... Cancer discovery 3 (10), 1156-1171, 2013 | 155* | 2013 |
| The Smc5-Smc6 DNA repair complex: bridging of the Smc5-Smc6 heads by the KLEISIN, Nse4, and non-Kleisin subunits J Palecek, S Vidot, M Feng, AJ Doherty, AR Lehmann Journal of Biological Chemistry 281 (48), 36952-36959, 2006 | 149 | 2006 |
| Chromosome 1q21. 3 amplification is a trackable biomarker and actionable target for breast cancer recurrence JY Goh, M Feng, W Wang, G Oguz, SMJM Yatim, PL Lee, Y Bao, TH Lim, ... Nature medicine 23 (11), 1319-1330, 2017 | 148 | 2017 |
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| Myc/miR-378/TOB2/cyclin D1 functional module regulates oncogenic transformation M Feng, Z Li, M Aau, CH Wong, X Yang, Q Yu Oncogene 30 (19), 2242-2251, 2011 | 102 | 2011 |
| HIFI-α activation underlies a functional switch in the paradoxical role of Ezh2/PRC2 in breast cancer S Mahara, PL Lee, M Feng, V Tergaonkar, WJ Chng, Q Yu Proceedings of the National Academy of Sciences 113 (26), E3735-E3744, 2016 | 94 | 2016 |
| Protein tyrosine phosphatase UBASH3B is overexpressed in triple-negative breast cancer and promotes invasion and metastasis ST Lee, M Feng, Y Wei, Z Li, Y Qiao, P Guan, X Jiang, CH Wong, K Huynh, ... Proceedings of the National Academy of Sciences 110 (27), 11121-11126, 2013 | 79 | 2013 |
| Roles of divalent metal ions in flap endonuclease–substrate interactions M Feng, D Patel, JJ Dervan, T Ceska, D Suck, I Haq, JR Sayers Nature structural & molecular biology 11 (5), 450-456, 2004 | 77 | 2004 |
| Stromal induction of BRD4 phosphorylation results in chromatin remodeling and BET inhibitor resistance in colorectal cancer W Wang, YA Tang, Q Xiao, WC Lee, B Cheng, Z Niu, G Oguz, M Feng, ... Nature communications 12 (1), 4441, 2021 | 64 | 2021 |
| The E3 ligase RING1 targets p53 for degradation and promotes cancer cell proliferation and survival J Shen, P Li, X Shao, Y Yang, X Liu, M Feng, Q Yu, R Hu, Z Wang Cancer research 78 (2), 359-371, 2018 | 59 | 2018 |
| Putative cis-Acting Stem-Loops in the 5′ Untranslated Region of the Severe Acute Respiratory Syndrome Coronavirus Can Substitute for Their Mouse Hepatitis … H Kang, M Feng, ME Schroeder, DP Giedroc, JL Leibowitz Journal of virology 80 (21), 10600-10614, 2006 | 59 | 2006 |
| Polymorphisms and Haplotypes in the Caspase-3, Caspase-7, and Caspase-8 Genes and Risk for Endometrial Cancer: A Population-Based, Case-Control Study … HL Xu, WH Xu, Q Cai, M Feng, J Long, W Zheng, YB Xiang, XO Shu Cancer Epidemiology Biomarkers & Prevention 18 (7), 2114-2122, 2009 | 55 | 2009 |
| Kinesin is an evolutionarily fine-tuned molecular ratchet-and-pawl device of decisively locked direction Z Wang, M Feng, W Zheng, D Fan Biophysical journal 93 (10), 3363-3372, 2007 | 55 | 2007 |
| miR-449 regulates CDK-Rb-E2F1 through an auto-regulatory feedback circuit M Feng, Q Yu Cell cycle 9 (2), 213-214, 2010 | 44 | 2010 |
| Direct observation of DNA threading in flap endonuclease complexes FA AlMalki, CS Flemming, J Zhang, M Feng, SE Sedelnikova, T Ceska, ... Nature structural & molecular biology 23 (7), 640-646, 2016 | 41 | 2016 |
| KDM6B Counteracts EZH2-Mediated Suppression of IGFBP5 to Confer Resistance to PI3K/AKT Inhibitor Treatment in Breast Cancer W Wang, KG Lim, M Feng, Y Bao, PL Lee, Y Cai, Y Chen, H Zhang, ... Molecular cancer therapeutics 17 (9), 1973-1983, 2018 | 37 | 2018 |
| Interactions of mutant and wild-type flap endonucleases with oligonucleotide substrates suggest an alternative model of DNA binding JJ Dervan, M Feng, D Patel, JA Grasby, PJ Artymiuk, TA Ceska, ... Proceedings of the National Academy of Sciences 99 (13), 8542-8547, 2002 | 31 | 2002 |
