Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Autophagy 12 (1), 1-222, 2016 | 13567* | 2016 |
XBP1 is essential for survival under hypoxic conditions and is required for tumor growth L Romero-Ramirez, H Cao, D Nelson, E Hammond, AH Lee, H Yoshida, ... Cancer research 64 (17), 5943-5947, 2004 | 695 | 2004 |
Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation C Koumenis, R Alarcon, E Hammond, P Sutphin, W Hoffman, M Murphy, ... Molecular and cellular biology, 2001 | 474 | 2001 |
Ultra-high dose rate (FLASH) radiotherapy: Silver bullet or fool's gold? JD Wilson, EM Hammond, GS Higgins, K Petersson Frontiers in oncology 9, 1563, 2020 | 458 | 2020 |
Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation E Fokas, R Prevo, JR Pollard, PM Reaper, PA Charlton, B Cornelissen, ... Cell death & disease 3 (12), e441-e441, 2012 | 458 | 2012 |
Regulation of autophagy by ATF4 in response to severe hypoxia T Rzymski, M Milani, L Pike, F Buffa, HR Mellor, L Winchester, I Pires, ... Oncogene 29 (31), 4424-4435, 2010 | 431 | 2010 |
Hypoxia links ATR and p53 through replication arrest EM Hammond, NC Denko, MJ Dorie, RT Abraham, AJ Giaccia Molecular and cellular biology 22 (6), 1834-1843, 2002 | 404 | 2002 |
ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation EM Hammond, MJ Dorie, AJ Giaccia Journal of Biological Chemistry 278 (14), 12207-12213, 2003 | 358 | 2003 |
The role of p53 in hypoxia-induced apoptosis EM Hammond, AJ Giaccia Biochemical and biophysical research communications 331 (3), 718-725, 2005 | 277 | 2005 |
Contextual synthetic lethality of cancer cell kill based on the tumor microenvironment N Chan, IM Pires, Z Bencokova, C Coackley, KR Luoto, N Bhogal, ... Cancer research 70 (20), 8045-8054, 2010 | 267 | 2010 |
ATM activation and signaling under hypoxic conditions Z Bencokova, MR Kaufmann, IM Pires, PS Lecane, AJ Giaccia, ... Molecular and cellular biology, 2009 | 258 | 2009 |
Targeting ATR in DNA damage response and cancer therapeutics E Fokas, R Prevo, EM Hammond, TB Brunner, WG McKenna, RJ Muschel Cancer treatment reviews 40 (1), 109-117, 2014 | 233 | 2014 |
The meaning, measurement and modification of hypoxia in the laboratory and the clinic EM Hammond, MC Asselin, D Forster, JPB O'Connor, JM Senra, ... Clinical oncology 26 (5), 277-288, 2014 | 228 | 2014 |
Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability IM Pires, Z Bencokova, M Milani, LK Folkes, JL Li, MR Stratford, AL Harris, ... Cancer research 70 (3), 925-935, 2010 | 223 | 2010 |
UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α Y Goto, L Zeng, CJ Yeom, Y Zhu, A Morinibu, K Shinomiya, M Kobayashi, ... Nature communications 6 (1), 6153, 2015 | 222 | 2015 |
Targeting radiation-resistant hypoxic tumour cells through ATR inhibition IM Pires, MM Olcina, S Anbalagan, JR Pollard, PM Reaper, PA Charlton, ... British journal of cancer 107 (2), 291-299, 2012 | 217 | 2012 |
The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia TM Ashton, E Fokas, LA Kunz-Schughart, LK Folkes, S Anbalagan, ... Nature communications 7 (1), 12308, 2016 | 203 | 2016 |
The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality TM Johnson, EM Hammond, A Giaccia, LD Attardi Nature genetics 37 (2), 145-152, 2005 | 164 | 2005 |
Optimization of 3, 5-dimethylisoxazole derivatives as potent bromodomain ligands DS Hewings, O Fedorov, P Filippakopoulos, S Martin, S Picaud, A Tumber, ... Journal of medicinal chemistry 56 (8), 3217-3227, 2013 | 161 | 2013 |
A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells K Phadwal, J Alegre-Abarrategui, AS Watson, L Pike, S Anbalagan, ... autophagy 8 (4), 677-689, 2012 | 161 | 2012 |