T cell activation is driven by an ADP-dependent glucokinase linking enhanced glycolysis with mitochondrial reactive oxygen species generation MM Kamiński, SW Sauer, M Kamiński, S Opp, T Ruppert, P Grigaravičius, ... Cell reports 2 (5), 1300-1315, 2012 | 204 | 2012 |
Therapeutic modulation of cerebral l-lysine metabolism in a mouse model for glutaric aciduria type I SW Sauer, S Opp, GF Hoffmann, DM Koeller, JG Okun, S Kölker Brain 134 (1), 157-170, 2011 | 120 | 2011 |
Bicaudal D2 facilitates the cytoplasmic trafficking and nuclear import of HIV-1 genomes during infection A Dharan, S Opp, O Abdel-Rahim, SK Keceli, S Imam, F Diaz-Griffero, ... Proceedings of the National Academy of Sciences 114 (50), E10707-E10716, 2017 | 117 | 2017 |
Ebselen, a small-molecule capsid inhibitor of HIV-1 replication S Thenin-Houssier, IMS De Vera, L Pedro-Rosa, A Brady, A Richard, ... Antimicrobial agents and chemotherapy 60 (4), 2195-2208, 2016 | 112 | 2016 |
Nup153 unlocks the nuclear pore complex for HIV-1 nuclear translocation in nondividing cells C Buffone, A Martinez-Lopez, T Fricke, S Opp, M Severgnini, I Cifola, ... Journal of virology 92 (19), 10.1128/jvi. 00648-18, 2018 | 104 | 2018 |
Glutaric aciduria type I and methylmalonic aciduria: simulation of cerebral import and export of accumulating neurotoxic dicarboxylic acids in in vitro models of the blood … SW Sauer, S Opp, A Mahringer, MM Kamiński, C Thiel, JG Okun, G Fricker, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1802 (6), 552-560, 2010 | 85 | 2010 |
Restriction of HIV-1 requires the N-terminal region of MxB as a capsid-binding motif but not as a nuclear localization signal B Schulte, C Buffone, S Opp, F Di Nunzio, DA De Souza Aranha Vieira, ... Journal of virology 89 (16), 8599-8610, 2015 | 75 | 2015 |
HIV-1 capsid is involved in post-nuclear entry steps NY Chen, L Zhou, PJ Gane, S Opp, NJ Ball, G Nicastro, M Zufferey, ... Retrovirology 13, 1-16, 2016 | 71 | 2016 |
BI-2 destabilizes HIV-1 cores during infection and Prevents Binding of CPSF6 to the HIV-1 Capsid T Fricke, C Buffone, S Opp, J Valle-Casuso, F Diaz-Griffero Retrovirology 11, 1-7, 2014 | 64 | 2014 |
Contribution of MxB oligomerization to HIV-1 capsid binding and restriction C Buffone, B Schulte, S Opp, F Diaz-Griffero Journal of virology 89 (6), 3285-3294, 2015 | 59 | 2015 |
Severe dysfunction of respiratory chain and cholesterol metabolism in Atp7b−/− mice as a model for Wilson disease SW Sauer, U Merle, S Opp, D Haas, GF Hoffmann, W Stremmel, JG Okun Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (12 …, 2011 | 59 | 2011 |
TRIM5α-mediated ubiquitin chain conjugation is required for inhibition of HIV-1 reverse transcription and capsid destabilization EM Campbell, J Weingart, P Sette, S Opp, J Sastri, SK O'Connor, S Talley, ... Journal of virology 90 (4), 1849-1857, 2016 | 54 | 2016 |
SUN2 overexpression deforms nuclear shape and inhibits HIV DA Donahue, S Amraoui, F Di Nunzio, C Kieffer, F Porrot, S Opp, ... Journal of virology 90 (8), 4199-4214, 2016 | 51 | 2016 |
Localization to detergent-resistant membranes and HIV-1 core entry inhibition correlate with HIV-1 restriction by SERINC5 B Schulte, A Selyutina, S Opp, A Herschhorn, JG Sodroski, M Pizzato, ... Virology 515, 52-65, 2018 | 47 | 2018 |
Understanding cerebral L-lysine metabolism: the role of L-pipecolate metabolism in Gcdh-deficient mice as a model for glutaric aciduria type I R Posset, S Opp, EA Struys, A Völkl, H Mohr, GF Hoffmann, S Kölker, ... Journal of inherited metabolic disease 38, 265-272, 2015 | 41 | 2015 |
MxB is not responsible for the blocking of HIV-1 infection observed in alpha interferon-treated cells S Opp, DASA Vieira, B Schulte, SK Chanda, F Diaz-Griffero Journal of virology 90 (6), 3056-3064, 2016 | 24 | 2016 |
Long-term exposure of human proximal tubule cells to hydroxycobalamin [c-lactam] as a possible model to study renal disease in methylmalonic acidurias SW Sauer, S Opp, A Haarmann, JG Okun, S Kölker, MA Morath Journal of inherited metabolic disease 32, 720-727, 2009 | 22 | 2009 |
Multifactorial modulation of susceptibility to l-lysine in an animal model of glutaric aciduria type I SW Sauer, S Opp, S Komatsuzaki, AE Blank, M Mittelbronn, P Burgard, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (5), 768-777, 2015 | 21 | 2015 |
The ability of SAMHD1 to block HIV-1 but not SIV requires expression of MxB C Buffone, J Kutzner, S Opp, A Martinez-Lopez, A Selyutina, SA Coggings, ... Virology 531, 260-268, 2019 | 19 | 2019 |
Sindbis virus with anti-OX40 overcomes the immunosuppressive tumor microenvironment of low-immunogenic tumors I Scherwitzl, S Opp, AM Hurtado, C Pampeno, C Loomis, K Kannan, M Yu, ... Molecular Therapy-Oncolytics 17, 431-447, 2020 | 18 | 2020 |