Cardiac glycosides are broad-spectrum senolytics A Guerrero, N Herranz, B Sun, V Wagner, S Gallage, R Guiho, K Wolter, ... Nature metabolism 1 (11), 1074-1088, 2019 | 287 | 2019 |
Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK … JR Apps, G Carreno, JM Gonzalez-Meljem, S Haston, R Guiho, ... Acta neuropathologica 135, 757-777, 2018 | 132 | 2018 |
Galactose‐modified duocarmycin prodrugs as senolytics A Guerrero, R Guiho, N Herranz, A Uren, DJ Withers, ... Aging Cell 19 (4), e13133, 2020 | 125 | 2020 |
Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer S Haston, E Gonzalez-Gualda, S Morsli, J Ge, V Reen, A Calderwood, ... Cancer Cell 41 (7), 1242-1260. e6, 2023 | 83 | 2023 |
The senescence-associated secretory phenotype mediates oncogene-induced senescence in pediatric pilocytic astrocytoma JL Buhl, F Selt, T Hielscher, R Guiho, J Ecker, F Sahm, J Ridinger, D Riehl, ... Clinical Cancer Research 25 (6), 1851-1866, 2019 | 72 | 2019 |
Cell senescence in neuropathology: A focus on neurodegeneration and tumours G Carreno, R Guiho, JP Martinez‐Barbera Neuropathology and Applied Neurobiology 47 (3), 359-378, 2021 | 52 | 2021 |
Bone microenvironment has an influence on the histological response of osteosarcoma to chemotherapy: retrospective analysis and preclinical modeling V Crenn, K Biteau, J Amiaud, C Dumars, R Guiho, L Vidal, LR Le Nail, ... American journal of cancer research 7 (11), 2333, 2017 | 42 | 2017 |
TRAIL delivered by mesenchymal stromal/stem cells counteracts tumor development in orthotopic Ewing sarcoma models R Guiho, K Biteau, G Grisendi, J Taurelle, M Chatelais, M Gantier, ... International Journal of Cancer 139 (12), 2802-2811, 2016 | 38 | 2016 |
L-MTP-PE and zoledronic acid combination in osteosarcoma: Preclinical evidence of positive therapeutic combination for clinical transfer K Biteau, R Guiho, M Chatelais, J Taurelle, J Chesneau, N Corradini, ... American journal of cancer research 6 (3), 677, 2016 | 37 | 2016 |
SHH pathway inhibition is protumourigenic in adamantinomatous craniopharyngioma G Carreno, JKR Boult, J Apps, JM Gonzalez-Meljem, S Haston, R Guiho, ... Endocrine-related cancer 26 (3), 355-366, 2019 | 29 | 2019 |
Clusterin inhibition using OGX-011 synergistically enhances zoledronic acid activity in osteosarcoma F Lamoureux, M Baud'huin, B Ory, R Guiho, A Zoubeidi, M Gleave, ... Oncotarget 5 (17), 7805, 2014 | 29 | 2014 |
BH3 mimetics targeting BCL-XL impact the senescent compartment of pilocytic astrocytoma F Selt, R Sigaud, G Valinciute, P Sievers, J Zaman, C Alcon, S Schmid, ... Neuro-oncology 25 (4), 735-747, 2023 | 23 | 2023 |
COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells D McHugh, B Sun, C Gutierrez-Muñoz, F Hernández-González, ... Nature Cell Biology 25 (12), 1804-1820, 2023 | 18 | 2023 |
TRAIL-based therapy in pediatric bone tumors: How to overcome resistance R Guiho, K Biteau, D Heymann, F Redini Future Oncology 11 (3), 535-542, 2015 | 18 | 2015 |
Jaw osteosarcoma models in mice: first description H Bertin, R Guilho, R Brion, J Amiaud, S Battaglia, A Moreau, ... Journal of Translational Medicine 17, 1-8, 2019 | 17 | 2019 |
A functional, new short isoform of death receptor 4 in Ewing's sarcoma cell lines may be involved in TRAIL sensitivity/resistance mechanisms G Picarda, S Surget, R Guiho, S Téletchéa, M Berreur, F Tirode, ... Molecular Cancer Research 10 (3), 336-346, 2012 | 16 | 2012 |
In vitro and in vivo discrepancy in inducing apoptosis by mesenchymal stromal cells delivering membrane-bound tumor necrosis factor–related apoptosis inducing ligand in … R Guiho, K Biteau, G Grisendi, M Chatelais, R Brion, J Taurelle, S Renault, ... Cytotherapy 20 (8), 1037-1045, 2018 | 15 | 2018 |
Development of a DNA damage-induced senescence model in osteoarthritic chondrocytes M Georget, A Defois, R Guiho, N Bon, S Allain, C Boyer, B Halgand, ... Aging (Albany NY) 15 (17), 8576, 2023 | 6 | 2023 |
Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokines D Kocher, L Cao, R Guiho, M Langhammer, YL Lai, P Becker, H Hamdi, ... Journal of Neuro-oncology 168 (2), 317-332, 2024 | 2 | 2024 |
TRAIL-Based Therapies Efficacy in Pediatric Bone Tumors Models Is Modulated by TRAIL Non-Apoptotic Pathway Activation via RIPK1 Recruitment R Brion, M Gantier, K Biteau, J Taurelle, B Brounais-Le Royer, ... Cancers 14 (22), 5627, 2022 | 2 | 2022 |