BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism D Boehm, V Calvanese, RD Dar, S Xing, S Schroeder, L Martins, K Aull, ... Cell cycle 12 (3), 452-462, 2013 | 271 | 2013 |
Metalloregulation of FRE1 and FRE2Homologs in Saccharomyces cerevisiae LJ Martins, LT Jensen, JR Simon, GL Keller, DR Winge Journal of Biological Chemistry 273 (37), 23716-23721, 1998 | 248 | 1998 |
BIRC2/cIAP1 is a negative regulator of HIV-1 transcription and can be targeted by Smac mimetics to promote reversal of viral latency L Pache, MS Dutra, AM Spivak, JM Marlett, JP Murry, Y Hwang, ... Cell host & microbe 18 (3), 345-353, 2015 | 149 | 2015 |
Silver (I) complexes of dichloromethane and 1, 2-dichloroethane MR Colsman, TD Newbound, LJ Marshall, MD Noirot, MM Miller, ... Journal of the American Chemical Society 112 (6), 2349-2362, 1990 | 126 | 1990 |
IFI16 targets the transcription factor Sp1 to suppress HIV-1 transcription and latency reactivation D Hotter, M Bosso, KL Jønsson, C Krapp, CM Stürzel, A Das, ... Cell host & microbe 25 (6), 858-872. e13, 2019 | 117 | 2019 |
Ex Vivo Bioactivity and HIV-1 Latency Reversal by Ingenol Dibenzoate and Panobinostat in Resting CD4+ T Cells from Aviremic Patients AM Spivak, A Bosque, AH Balch, D Smyth, L Martins, V Planelles Antimicrobial agents and chemotherapy 59 (10), 5984-5991, 2015 | 101 | 2015 |
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation A Bosque, KA Nilson, AB Macedo, AM Spivak, NM Archin, ... Cell reports 18 (5), 1324-1334, 2017 | 91 | 2017 |
Magnetic circular dichroism studies of exogenous ligand and substrate binding to the non-heme ferrous active site in phthalate dioxygenase EG Pavel, LJ Martins, WR Ellis Jr, EI Solomon Chemistry & Biology 1 (3), 173-183, 1994 | 70 | 1994 |
Modeling HIV-1 latency in primary T cells using a replication-competent virus LJ Martins, P Bonczkowski, AM Spivak, W De Spiegelaere, CL Novis, ... AIDS research and human retroviruses 32 (2), 187-193, 2016 | 65 | 2016 |
HIV testing history and access to treatment among migrants living with HIV in Europe I Fakoya, D Álvarez‐Del Arco, S Monge, AJ Copas, AF Gennotte, ... Journal of the International AIDS Society 21, e25123, 2018 | 61 | 2018 |
Thiol based redox signaling in plant nucleus L Martins, JA Trujillo-Hernandez, JP Reichheld Frontiers in Plant Science 9, 705, 2018 | 48 | 2018 |
Transcriptomic analysis implicates the p53 signaling pathway in the establishment of HIV-1 latency in central memory CD4 T cells in an in vitro model CH White, B Moesker, N Beliakova-Bethell, LJ Martins, CA Spina, ... PLoS Pathogens 12 (11), e1006026, 2016 | 43 | 2016 |
A second update on mapping the human genetic architecture of COVID-19 M Kanai, SJ Andrews, M Cordioli, C Stevens, BM Neale, M Daly, A Ganna, ... Nature 621 (7977), E7-E26, 2023 | 42 | 2023 |
Redox modification of the iron-sulfur glutaredoxin GRXS17 activates holdase activity and protects plants from heat stress L Martins, J Knuesting, L Bariat, A Dard, SA Freibert, CH Marchand, ... Plant Physiology 184 (2), 676-692, 2020 | 42 | 2020 |
Janus kinase inhibition suppresses PKC-induced cytokine release without affecting HIV-1 latency reversal ex vivo AM Spivak, ET Larragoite, MKL Coletti, AB Macedo, LJ Martins, A Bosque, ... Retrovirology 13, 1-9, 2016 | 36 | 2016 |
Structures of Wild-Type Chloromet and L103N Hydroxomet Themiste zostericola Myohemerythrins at 1.8 Å Resolution LJ Martins, CP Hill, WR Ellis Biochemistry 36 (23), 7044-7049, 1997 | 33 | 1997 |
Functional role of leucine-103 in myohemerythrin GM Raner, LJ Martins, WR Ellis Biochemistry 36 (23), 7037-7043, 1997 | 27 | 1997 |
Mycobacterium tuberculosis reactivates latent HIV-1 in T cells in vitro EC Larson, CL Novis, LJ Martins, AB Macedo, KE Kimball, A Bosque, ... PLoS One 12 (9), e0185162, 2017 | 26 | 2017 |
Sensors that mediate copper-specific activation and repression of gene expression DR Winge, JA Graden, MC Posewitz, LJ Martins, LT Jensen, JR Simon JBIC Journal of Biological Inorganic Chemistry 2, 2-10, 1997 | 26 | 1997 |
Synthetic ingenols maximize protein kinase C-induced HIV-1 latency reversal AM Spivak, RA Nell, M Petersen, L Martins, P Sebahar, RE Looper, ... Antimicrobial agents and chemotherapy 62 (11), 10.1128/aac. 01361-18, 2018 | 19 | 2018 |