| Decoding the mechanisms of chimeric antigen receptor (CAR) T cell-mediated killing of tumors: insights from granzyme and Fas inhibition MJ Montalvo, IN Bandey, A Rezvan, KL Wu, A Saeedi, R Kulkarni, Y Li, ... Cell Death & Disease 15 (2), 109, 2024 | 5 | 2024 |
| Senti-202, a selective, off-the-shelf, preclinical CAR-NK cell therapy with CD33 and/or FLT3 activating CAR, healthy cell protection from endomucin (EMCN) inhibitory CAR and … B Garrison, H Deng, G Yucel, NW Frankel, R Gordley, M Hung, D Lee, ... Blood 140 (Supplement 1), 4531-4532, 2022 | 5 | 2022 |
| Calibrated release IL15 bivalent CD33 and/or FLT3 and NOT Emcn logic gated gene circuit CAR-NK cell therapy (SENTI-202) in venetoclax resistant patient derived xenograft acute … M Muftuoglu, M Basyal, L Li, J Lv, LB Ostermann, R Zhao, B Ke, ... Blood 142, 4831, 2023 | 2 | 2023 |
| Preclinical development of SENTI-202, an off-the-shelf logic gated CAR-NK cell therapy, for the treatment of CD33/FLT3+ hematologic malignancies including AML A Gonzalez, E Hong, G Yucel, E Leitner, P Chinta, H Deng, I Li, A Lam, ... Cancer Research 83 (7_Supplement), 3195-3195, 2023 | 2 | 2023 |
| Precision off-the-shelf natural killer cell therapies for oncology with logic-gated gene circuits NW Frankel, H Deng, G Yucel, M Gainer, N Leemans, A Lam, Y Li, ... Cell Reports 43 (5), 2024 | 1 | 2024 |
| Preclinical data supporting the Phase 1 trial design of SENTI-202, a next generation allogeneic logic-gated selective CAR NK cell therapy, engineered to overcome key … D Kaveri, P Chinta, E Leitner, L Naitmazi, G Yucel, M Tian, N Almudhfar, ... Cancer Research 84 (6_Supplement), 1333-1333, 2024 | | 2024 |
| Tunable Universal OR-gated CAR T cells for AML MY Siddiqui, J Chen, M Loffredo, S Lee, H Deng, Y Li, N Leemans, T Lu, ... bioRxiv, 2024.04. 13.589307, 2024 | | 2024 |
| 257 NOT gate gene circuits expand the range of tumor-associated antigens addressable by CAR-NK and-T cell therapies NW Frankel, A Roguev, M Gainer, II Caradonna, T Hua, H Deng, G Yucel, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
