Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1 RGW Verhaak, KA Hoadley, E Purdom, V Wang, Y Qi, MD Wilkerson, ... Cancer cell 17 (1), 98-110, 2010 | 7908 | 2010 |
Comprehensive genomic characterization defines human glioblastoma genes and core pathways R McLendon, A Friedman, D Bigner, EG Van, Meir, DJ Brat, ... Nature 455 (7216), 1061-1068, 2008 | 7339 | 2008 |
Carcinoma-associated fibroblast–like differentiation of human mesenchymal stem cells PJ Mishra, PJ Mishra, R Humeniuk, DJ Medina, G Alexe, JP Mesirov, ... Cancer research 68 (11), 4331-4339, 2008 | 1066 | 2008 |
Targeting MYCN in neuroblastoma by BET bromodomain inhibition A Puissant, SM Frumm, G Alexe, CF Bassil, J Qi, YH Chanthery, ... Cancer discovery 3 (3), 308-323, 2013 | 711 | 2013 |
The genomic landscape of pediatric Ewing sarcoma BD Crompton, C Stewart, A Taylor-Weiner, G Alexe, KC Kurek, ... Cancer discovery 4 (11), 1326-1341, 2014 | 511 | 2014 |
Origin and differentiation of human memory CD8 T cells after vaccination RS Akondy, M Fitch, S Edupuganti, S Yang, HT Kissick, KW Li, ... Nature 552 (7685), 362-367, 2017 | 510 | 2017 |
MDM2 SNP309 accelerates tumor formation in a gender-specific and hormone-dependent manner GL Bond, KM Hirshfield, T Kirchhoff, G Alexe, EE Bond, H Robins, F Bartel, ... Cancer research 66 (10), 5104-5110, 2006 | 357 | 2006 |
Identifying mRNA targets of microRNA dysregulated in cancer: with application to clear cell Renal Cell Carcinoma H Liu, AR Brannon, AR Reddy, G Alexe, MW Seiler, A Arreola, JH Oza, ... BMC systems biology 4, 1-17, 2010 | 311 | 2010 |
Identification of a microRNA panel for clear-cell kidney cancer D Juan, G Alexe, T Antes, H Liu, A Madabhushi, C Delisi, S Ganesan, ... Urology 75 (4), 835-841, 2010 | 270 | 2010 |
High expression of lymphocyte-associated genes in node-negative HER2+ breast cancers correlates with lower recurrence rates G Alexe, GS Dalgin, D Scanfeld, P Tamayo, JP Mesirov, C DeLisi, L Harris, ... Cancer research 67 (22), 10669-10676, 2007 | 245 | 2007 |
Consensus algorithms for the generation of all maximal bicliques G Alexe, S Alexe, Y Crama, S Foldes, PL Hammer, B Simeone Discrete Applied Mathematics 145 (1), 11-21, 2004 | 225 | 2004 |
In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling PG Miller, F Al-Shahrour, KA Hartwell, LP Chu, M Järås, RV Puram, ... Cancer cell 24 (1), 45-58, 2013 | 179 | 2013 |
Transforming growth factor-β signaling: emerging stem cell target in metastatic breast cancer? AR Tan, G Alexe, M Reiss Breast cancer research and treatment 115, 453-495, 2009 | 163 | 2009 |
Antigen availability determines CD8+ T cell-dendritic cell interaction kinetics and memory fate decisions SE Henrickson, M Perro, SM Loughhead, B Senman, S Stutte, M Quigley, ... Immunity 39 (3), 496-507, 2013 | 159 | 2013 |
Tight regulation of memory CD8+ T cells limits their effectiveness during sustained high viral load EE West, B Youngblood, WG Tan, HT Jin, K Araki, G Alexe, BT Konieczny, ... Immunity 35 (2), 285-298, 2011 | 155 | 2011 |
Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth TU Barbie, G Alexe, AR Aref, S Li, Z Zhu, X Zhang, Y Imamura, TC Thai, ... The Journal of clinical investigation 124 (12), 5411-5423, 2014 | 154 | 2014 |
SYK is a critical regulator of FLT3 in acute myeloid leukemia A Puissant, N Fenouille, G Alexe, Y Pikman, CF Bassil, S Mehta, J Du, ... Cancer cell 25 (2), 226-242, 2014 | 154 | 2014 |
Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation AA Lane, B Chapuy, CY Lin, T Tivey, H Li, EC Townsend, ... Nature genetics 46 (6), 618-623, 2014 | 147 | 2014 |
EWS/FLI confers tumor cell synthetic lethality to CDK12 inhibition in Ewing sarcoma AB Iniguez, B Stolte, EJ Wang, AS Conway, G Alexe, NV Dharia, ... Cancer cell 33 (2), 202-216. e6, 2018 | 146 | 2018 |
Ovarian cancer detection by logical analysis of proteomic data G Alexe, S Alexe, LA Liotta, E Petricoin, M Reiss, PL Hammer Proteomics 4 (3), 766-783, 2004 | 143 | 2004 |