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Sarah O'Keefe
Sarah O'Keefe
在 helsinki.fi 的电子邮件经过验证
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引用次数
引用次数
年份
Ipomoeassin F binds Sec61α to inhibit protein translocation
G Zong, Z Hu, S O’keefe, D Tranter, MJ Iannotti, L Baron, B Hall, ...
Journal of the American Chemical Society 141 (21), 8450-8461, 2019
692019
Eeyarestatin compounds selectively enhance Sec61-mediated Ca2+ leakage from the endoplasmic reticulum
I Gamayun, S O'Keefe, T Pick, MC Klein, D Nguyen, C McKibbin, ...
Cell chemical biology 26 (4), 571-583. e6, 2019
482019
An alternative pathway for membrane protein biogenesis at the endoplasmic reticulum
S O’keefe, G Zong, KB Duah, LE Andrews, WQ Shi, S High
Communications Biology 4 (1), 828, 2021
392021
Membrane protein biogenesis at the ER: the highways and byways
S O'Keefe, MR Pool, S High
The FEBS Journal 289 (22), 6835-6862, 2022
342022
Ipomoeassin-F inhibits the in vitro biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor
S O'Keefe, P Roboti, KB Duah, G Zong, H Schneider, WQ Shi, S High
Journal of Cell Science 134 (4), jcs257758, 2021
282021
Characterizing the selectivity of ER α-glucosidase inhibitors
S O’Keefe, QP Roebuck, I Nakagome, S Hirono, A Kato, R Nash, S High
Glycobiology 29 (7), 530-542, 2019
212019
Ring expansion leads to a more potent analogue of Ipomoeassin F
G Zong, Z Hu, KB Duah, LE Andrews, J Zhou, S O’Keefe, L Whisenhunt, ...
The Journal of organic chemistry 85 (24), 16226-16235, 2020
192020
Membrane translocation at the ER: with a little help from my friends
S O'Keefe, S High
The FEBS Journal 287 (21), 4607-4611, 2020
132020
The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity
H Stewart, Y Lu, S O’Keefe, A Valpadashi, LD Cruz-Zaragoza, HA Michel, ...
Iscience 26 (11), 2023
102023
Eeyarestatin 24 impairs SecYEG‐dependent protein trafficking and inhibits growth of clinically relevant pathogens
M Steenhuis, GM Koningstein, J Oswald, T Pick, S O’Keefe, HG Koch, ...
Molecular Microbiology 115 (1), 28-40, 2021
102021
Proteomics identifies substrates and a novel component in hSnd2-dependent ER protein targeting
A Tirincsi, S O’Keefe, D Nguyen, M Sicking, J Dudek, F Förster, M Jung, ...
Cells 11 (18), 2925, 2022
82022
Ipomoeassin-F disrupts multiple aspects of secretory protein biogenesis
P Roboti, S O’Keefe, KB Duah, WQ Shi, S High
Scientific Reports 11 (1), 11562, 2021
82021
Dual action of eeyarestatin 24 on sec-dependent protein secretion and bacterial DNA
AB Schäfer, M Steenhuis, KK Jim, J Neef, S O’Keefe, RC Whitehead, ...
ACS infectious diseases 9 (2), 253-269, 2023
62023
Biochemical and biological assays of mycolactone-mediated inhibition of Sec61
S O’Keefe, S High, C Demangel
Mycobacterium Ulcerans: Methods and Protocols, 163-181, 2022
52022
Synthesis, Biological Evaluation and Docking Studies of Ring-Opened Analogues of Ipomoeassin F
S O’Keefe, P Bhadra, KB Duah, G Zong, L Tenay, L Andrews, ...
Molecules 27 (14), 4419, 2022
12022
Small molecule inhibitors targeting protein biogenesis at the endoplasmic reticulum
S O'Keefe
PQDT-Global, 2019
12019
Erratum: Characterizing the selectivity of ER α-glucosidase inhibitors (Glycobiology (2019) 29: 7 (530-542
S O'Keefe, QP Roebuck, I Nakagome, S Hirono, A Kato, R Nash, S High
Glycobiology 33 (6), 525, 2023
2023
Biology-directed and in silico-aided design liberates a potent, simplified and ipomoeassin-F-derived Sec61 inhibitor
S O'Keefe, P Bhadra, K Duah, G Zong, L Tenay, L Andrews, H Schneider, ...
2022
The road less travelled: membrane protein biogenesis at the ER
S O'Keefe
Microbiology, 2021
2021
Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis
J Chang, A Pickard, JA Herrera, S O’Keefe, M Hartshorn, R Garva, ...
bioRxiv, 2021.03. 25.436925, 2021
2021
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