Early diagnosis by genetic analysis of differentiated thyroid cancer metastases in small lymph nodes F Arturi, D Russo, D Giuffrida, A Ippolito, N Perrotti, R Vigneri, S Filetti The Journal of Clinical Endocrinology & Metabolism 82 (5), 1638-1641, 1997 | 250 | 1997 |
Activation of serum-and glucocorticoid-induced protein kinase (Sgk) by cyclic AMP and insulin N Perrotti, RA He, SA Phillips, CR Haft, SI Taylor Journal of Biological Chemistry 276 (12), 9406-9412, 2001 | 187 | 2001 |
sgk: an essential convergence point for peptide and steroid hormone regulation of ENaC-mediated Na+transport CJ Faletti, N Perrotti, SI Taylor, BL Blazer-Yost American Journal of Physiology-Cell Physiology 282 (3), C494-C500, 2002 | 173 | 2002 |
Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation R Amato, L D’Antona, G Porciatti, V Agosti, M Menniti, C Rinaldo, N Costa, ... Journal of molecular medicine 87, 1221-1239, 2009 | 121 | 2009 |
Colorectal carcinoma cells—regulation of survival and growth by SGK1 F Lang, N Perrotti, C Stournaras The international journal of biochemistry & cell biology 42 (10), 1571-1575, 2010 | 117 | 2010 |
Angiotensin-converting enzyme gene polymorphism is associated with endothelium-dependent vasodilation in never treated hypertensive patients F Perticone, R Ceravolo, R Maio, G Ventura, A Zingone, N Perrotti, ... Hypertension 31 (4), 900-905, 1998 | 112 | 1998 |
Determination of SGK1 mRNA in non-small cell lung cancer samples underlines high expression in squamous cell carcinomas C Abbruzzese, S Mattarocci, L Pizzuti, AM Mileo, P Visca, B Antoniani, ... Journal of experimental & clinical cancer research 31, 1-7, 2012 | 110 | 2012 |
Protection of human endothelial cells from oxidative stress: role of Ras-ERK1/2 signaling G Cuda, R Paternò, R Ceravolo, M Candigliota, N Perrotti, F Perticone, ... Circulation 105 (8), 968-974, 2002 | 110 | 2002 |
Deletion polymorphism of angiotensin-converting enzyme gene and left ventricular hypertrophy in southern Italian patients F Perticone, R Ceravolo, C Cosco, M Trapasso, A Zingone, P Malatesta, ... Journal of the American College of Cardiology 29 (2), 365-369, 1997 | 100 | 1997 |
Early molecular and behavioral response to lipopolysaccharide in the WAG/Rij rat model of absence epilepsy and depressive-like behavior, involves interplay between AMPK, AKT … E Russo, F Andreozzi, R Iuliano, V Dattilo, T Procopio, G Fiume, S Mimmi, ... Brain, Behavior, and Immunity 42, 157-168, 2014 | 99 | 2014 |
Insulin stimulates phosphorylation of a 120-kDa glycoprotein substrate (pp120) for the receptor-associated protein kinase in intact H-35 hepatoma cells. N Perrotti, D Accili, B Marcus-Samuels, RW Rees-Jones, SI Taylor Proceedings of the National Academy of Sciences 84 (10), 3137-3140, 1987 | 95 | 1987 |
Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy C Talarico, L D'Antona, D Scumaci, A Barone, F Gigliotti, CV Fiumara, ... Oncotarget 6 (35), 37511, 2015 | 92 | 2015 |
SGK1, the new player in the game of resistance: chemo-radio molecular target and strategy for inhibition C Talarico, V Dattilo, L D'antona, M Menniti, C Bianco, F Ortuso, S Alcaro, ... Cellular physiology and biochemistry 39 (5), 1863-1876, 2016 | 85 | 2016 |
SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells C Talarico, V Dattilo, L D'Antona, A Barone, N Amodio, S Belviso, ... Oncotarget 7 (13), 15868, 2016 | 76 | 2016 |
IL-2 signals through Sgk1 and inhibits proliferation and apoptosis in kidney cancer cells R Amato, M Menniti, V Agosti, R Boito, N Costa, HM Bond, V Barbieri, ... Journal of molecular medicine 85, 707-721, 2007 | 72 | 2007 |
SI113, a specific inhibitor of the Sgk1 kinase activity that counteracts cancer cell proliferation L D''antona, R Amato, C Talarico, F Ortuso, M Menniti, V Dattilo, R Iuliano, ... Cellular physiology and biochemistry 35 (5), 2006-2018, 2015 | 70 | 2015 |
Sgk1 enhances RANBP1 transcript levels and decreases taxol sensitivity in RKO colon carcinoma cells R Amato, D Scumaci, L D'antona, R Iuliano, M Menniti, M Di Sanzo, ... Oncogene 32 (38), 4572-4578, 2013 | 70 | 2013 |
Direct evidence for a stimulatory effect of hyperglycemia per se on peripheral glucose disposal in type II diabetes. B Capaldo, D Santoro, G Riccardi, N Perrotti, L Sacca The Journal of clinical investigation 77 (4), 1285-1290, 1986 | 69 | 1986 |
The SGK1 inhibitor SI113 induces autophagy, apoptosis, and endoplasmic reticulum stress in endometrial cancer cells D Conza, P Mirra, G Calì, T Tortora, L Insabato, F Fiory, S Schenone, ... Journal of cellular physiology 232 (12), 3735-3743, 2017 | 66 | 2017 |
Tissue distribution and subcellular localization of an endogenous substrate (ppl20) for the insulin receptor-associated tyrosine kinase D ACCILI, N PERROTTI, R REES-JONES, SI TAYLOR Endocrinology 119 (3), 1274-1280, 1986 | 66 | 1986 |