Tip60 HAT Activity Mediates APP Induced Lethality and Apoptotic Cell Death in the CNS of a Drosophila Alzheimer's Disease Model SK Pirooznia, J Sarthi, AA Johnson, MS Toth, K Chiu, S Koduri, F Elefant Public Library of Science 7 (7), e41776, 2012 | 99 | 2012 |
Epigenetic Control of Learning and Memory in Drosophila by Tip60 HAT Action S Xu, R Wilf, T Menon, P Panikker, J Sarthi, F Elefant Genetics 198 (4), 1571-1586, 2014 | 76 | 2014 |
Increasing Tip60 HAT levels rescues axonal transport defects and associated behavioral phenotypes in a Drosophila Alzheimer's disease model AA Johnson, J Sarthi, SK Pirooznia, W Reube, F Elefant Journal of Neuroscience 33 (17), 7535-7547, 2013 | 76 | 2013 |
Microarray analysis uncovers a role for Tip60 in nervous system function and general metabolism M Lorbeck, K Pirooznia, J Sarthi, X Zhu, F Elefant PLoS One 6 (4), e18412, 2011 | 55 | 2011 |
Restoring Tip60 HAT/HDAC2 balance in the neurodegenerative brain relieves epigenetic transcriptional repression and reinstates cognition P Panikker, SJ Xu, H Zhang, J Sarthi, M Beaver, A Sheth, S Akhter, ... Journal of Neuroscience 38 (19), 4569-4583, 2018 | 53 | 2018 |
Smc5/6 is a telomere-associated complex that regulates Sir4 binding and TPE S Moradi-Fard, J Sarthi, M Tittel-Elmer, M Lalonde, E Cusanelli, ... PLoS genetics 12 (8), e1006268, 2016 | 49 | 2016 |
dTip60 HAT Activity Controls Synaptic Bouton Expansion at the Drosophila Neuromuscular Junction J Sarthi, F Elefant PloS one 6 (10), e26202, 2011 | 40 | 2011 |
Key role of down-regulated in adenoma (SLC26A3) chloride/bicarbonate exchanger in linaclotide-stimulated intestinal bicarbonate secretion upon loss of CFTR function. SZM Sarthi JB, Trumbull AM, Abazari SM, van Unen V, Chan JE, Jiang Y ... bioRxiv, 2024 | 2* | 2024 |
DRA involvement in linaclotide stimulated bicarbonate secretion during loss of CFTR function JB Sarthi, AM Trumbull, SM Abazari, V van Unen, JE Chan, Y Jiang, ... JCI insight, 2024 | | 2024 |
364 Linaclotide-stimulated SLC26A3 (downregulated in adenoma) membrane trafficking in healthy and cystic fibrosis small intestine J Sarthi, Z Sellers, J Gammons Journal of Cystic Fibrosis 22, S184-S185, 2023 | | 2023 |
222 Signaling mechanisms driving CFTR-independent chloride secretion in Calu-3 cells S Abazari, G Masarweh, J Gammons, J Sarthi, Z Sellers Journal of Cystic Fibrosis 22, S114, 2023 | | 2023 |
EPS3. 09 Transcriptomic and Functional Analysis of Chloride, Bicarbonate, and Proton Secretion Along the Crypt-Villus Axis in Human Intestine: lessons for cystic fibrosis G Masarweh, V Van Unen, Y Jiang, JB Sarthi, JE Chan, ZM Sellers Journal of Cystic Fibrosis 22, S45, 2023 | | 2023 |
203 Re-evaluating the expression profile of SLC26A3 (down-regulated in adenoma) chloride/bicarbonate exchanger in the small intestine using human models: Implications for … J Sarthi, V van Unen, J Chan, C Kuo, Z Sellers Journal of Cystic Fibrosis 21, S119-S121, 2022 | | 2022 |
826: LINACLOTIDE INCREASES DUODENAL BICARBONATE SECRETION INDEPENDENT OF CFTR BY ALTERING APICAL MEMBRANE DYNAMICS OF DRA AND NHE3 AM Trumbull, S Abazari, JB Sarthi, V van Unen, JE Chan, C Kuo, ... Gastroenterology 162 (7), S-205, 2022 | | 2022 |
IRBIT as a Regulator of Bicarbonate Transport in the Small Intestine JB Sarthi, V Van Unen, JE Chan, S Abazari, A Trumbull, A Guh‐Siesel, ... The FASEB Journal 36, 2022 | | 2022 |
LINACLOTIDE AS A POTENTIAL BICARBONATE-CORRECTING THERAPY IN CF INTESTINE AM Trumbull, SM Abazari, JB Sarthi, ZM Sellers PEDIATRIC PULMONOLOGY 55, S121-S121, 2020 | | 2020 |
DIFFERENCES IN PROSTAGLANDIN E-2 RECEPTOR MEDIATION OF BICARBONATE SECRETION BETWEEN CYSTIC FIBROSIS AIRWAYS AND INTESTINE SM Abazari, AM Trumbull, JB Sarthi, A Farinazzo, ZM Sellers PEDIATRIC PULMONOLOGY 55, S59-S59, 2020 | | 2020 |
Smc5/6 is a telomeric complex that regulates Sir4 binding and TPE S Moradi-Fard, J Sarthi, M Tittel-Elmer, M Lalonde, E Cusanelli, ... Biochemistry and Cell Biology 95 (2), 179-181, 2017 | | 2017 |
An Epigenetic role for Tip60 in synaptic plasticity and neurodegenerative diseases JB Sarthi Drexel University, 2013 | | 2013 |
Tip60 HAT Activity Mediates APP Induced Lethality and Apoptotic Cell Death in the CNS SK Pirooznia, J Sarthi, AA Johnson, MS Toth, K Chiu | | 2012 |