| Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing JK Nuñez, J Chen, GC Pommier, JZ Cogan, JM Replogle, C Adriaens, ... Cell 184 (9), 2503-2519. e17, 2021 | 391 | 2021 |
| ecDNA hubs drive cooperative intermolecular oncogene expression KL Hung, KE Yost, L Xie, Q Shi, K Helmsauer, J Luebeck, R Schöpflin, ... Nature 600 (7890), 731-736, 2021 | 158 | 2021 |
| Engineering protein-secreting plasma cells by homology-directed repair in primary human B cells KL Hung, I Meitlis, M Hale, CY Chen, S Singh, SW Jackson, CH Miao, ... Molecular Therapy 26 (2), 456-467, 2018 | 111 | 2018 |
| The evolutionary dynamics of extrachromosomal DNA in human cancers JT Lange, JC Rose, CY Chen, Y Pichugin, L Xie, J Tang, KL Hung, ... Nature Genetics 54 (10), 1527-1533, 2022 | 75* | 2022 |
| Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH KL Hung, J Luebeck, SR Dehkordi, CI Colón, R Li, ITL Wong, C Coruh, ... Nature Genetics 54, 1746-1754, 2022 | 57 | 2022 |
| Wnt signaling and tbx16 form a bistable switch to commit bipotential progenitors to mesoderm CM Bouldin, AJ Manning, YH Peng, GH Farr III, KL Hung, A Dong, ... Development 142 (14), 2499-2507, 2015 | 55 | 2015 |
| A functional taxonomy of tumor suppression in oncogenic KRAS–driven lung cancer H Cai, SK Chew, C Li, MK Tsai, L Andrejka, CW Murray, NW Hughes, ... Cancer discovery 11 (7), 1754-1773, 2021 | 36 | 2021 |
| Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells R Chamorro González, T Conrad, MC Stöber, R Xu, M Giurgiu, ... Nature Genetics 55 (5), 880-890, 2023 | 22 | 2023 |
| Gene regulation on extrachromosomal DNA KL Hung, PS Mischel, HY Chang Nature structural & molecular biology 29 (8), 736-744, 2022 | 20 | 2022 |
| Ex vivo engineered human plasma cells exhibit robust protein secretion and long-term engraftment in vivo RYH Cheng, KL Hung, T Zhang, CM Stoffers, AR Ott, ER Suchland, ... Nature Communications 13 (1), 6110, 2022 | 15 | 2022 |
| The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner A Gonzalez-Sandoval, K Pekrun, S Tsuji, F Zhang, KL Hung, HY Chang, ... Nature Communications 14 (1), 2448, 2023 | 14 | 2023 |
| 132. Targeting the BTK locus in primary human hematopoietic cells with TALENs and AAV donor template C Clough, Y Wang, IF Khan, S Singh, K Hung, DJ Rawlings Molecular Therapy 24, S54, 2016 | 7 | 2016 |
| Oncogene convergence in extrachromosomal DNA hubs NE Weiser, KL Hung, HY Chang Cancer discovery 12 (5), 1195-1198, 2022 | 6 | 2022 |
| Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma OS Chapman, J Luebeck, S Sridhar, ITL Wong, D Dixit, S Wang, G Prasad, ... Nature genetics 55 (12), 2189-2199, 2023 | 5 | 2023 |
| Engraftable cell-based immunotherapy for long-term delivery of therapeutic proteins DJ Rawlings, R James, SW Jackson, I Khan, K Hung US Patent App. 15/921,353, 2018 | 3* | 2018 |
| 569. Precision Editing of the WAS Locus via Homologous Recombination in Primary Human Hematopoietic Cells Mediated by Either TALEN or CRISPR/Cas Nucleases IF Khan, Y Wang, C Clough, S Singh, K Hung, DJ Rawlings Molecular Therapy 24, S227, 2016 | 1 | 2016 |
| CoRAL accurately resolves extrachromosomal DNA genome structures with long-read sequencing K Zhu, MG Jones, J Luebeck, X Bu, H Yi, KL Hung, ITL Wong, S Zhang, ... International Conference on Research in Computational Molecular Biology, 454-457, 2024 | | 2024 |
| The origins and clinical impact of extrachromosomal DNA across 39 cancers C Bailey, O Pich, K Thol, J Luebeck, G Stavrou, TB Watkins, NE Weiser, ... Cancer Research 84 (6_Supplement), 3887-3887, 2024 | | 2024 |
| Disparate pathways for extrachromosomal DNA biogenesis and genomic DNA repair JC Rose, ITL Wong, B Daniel, MG Jones, KE Yost, KL Hung, EJ Curtis, ... bioRxiv, 2023 | | 2023 |
| Coordinated inheritance of extrachromosomal DNA species in human cancer cells KL Hung, MG Jones, ITL Wong, JT Lange, J Luebeck, E Scanu, BJ He, ... bioRxiv, 2023 | | 2023 |
Howard Y. ChangStanford University在 stanford.edu 的电子邮件经过验证
