| A novel multiple-stage antimalarial agent that inhibits protein synthesis B Baragaña, I Hallyburton, MCS Lee, NR Norcross, R Grimaldi, TD Otto, ... Nature 522 (7556), 315-320, 2015 | 444 | 2015 |
| Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need MC Field, D Horn, AH Fairlamb, MAJ Ferguson, DW Gray, KD Read, ... Nature Reviews Microbiology 15 (4), 217-231, 2017 | 410 | 2017 |
| New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: an open resource I Pena, M Pilar Manzano, J Cantizani, A Kessler, J Alonso-Padilla, ... Scientific reports 5 (1), 8771, 2015 | 269 | 2015 |
| Novel signal transduction pathway mediating endothelium-dependent beta-adrenoceptor vasorelaxation in rat thoracic aorta. DW Gray, I Marshall British journal of pharmacology 107 (3), 684, 1992 | 228 | 1992 |
| Pharmacological properties of the enhanced-affinity glucocorticoid fluticasone furoate in vitro and in an in vivo model of respiratory inflammatory disease M Salter, K Biggadike, JL Matthews, MR West, MV Haase, SN Farrow, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 293 (3 …, 2007 | 195 | 2007 |
| Human α‐calcitonin gene‐related peptide stimulates adenylate cyclase and guanylate cyclase and relaxes rat thoracic aorta by releasing nitric oxide DW Gray, I Marshall British journal of pharmacology 107 (3), 691-696, 1992 | 177 | 1992 |
| Comparison of a high-throughput high-content intracellular Leishmania donovani assay with an axenic amastigote assay M De Rycker, I Hallyburton, J Thomas, L Campbell, S Wyllie, D Joshi, ... Antimicrobial agents and chemotherapy 57 (7), 2913-2922, 2013 | 167 | 2013 |
| Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition S Wyllie, S Brand, M Thomas, M De Rycker, C Chung, I Pena, ... Proceedings of the National Academy of Sciences 116 (19), 9318-9323, 2019 | 128 | 2019 |
| Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis S Wyllie, M Thomas, S Patterson, S Crouch, M De Rycker, R Lowe, ... Nature 560 (7717), 192-197, 2018 | 127 | 2018 |
| Nitric oxide synthesis inhibitors attenuate calcitonin gene-related peptide endothelium-dependent vasorelaxation in rat aorta DW Gray, I Marshall European journal of pharmacology 212 (1), 37-42, 1992 | 115 | 1992 |
| Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis B Baragaña, B Forte, R Choi, S Nakazawa Hewitt, JA Bueren-Calabuig, ... Proceedings of the National Academy of Sciences 116 (14), 7015-7020, 2019 | 109 | 2019 |
| Identification of small molecule inhibitors of pre-mRNA splicing A Pawellek, S McElroy, T Samatov, L Mitchell, A Woodland, U Ryder, ... Journal of Biological Chemistry 289 (50), 34683-34698, 2014 | 88 | 2014 |
| Development of Trypanosoma cruzi in vitro assays to identify compounds suitable for progression in Chagas’ disease drug discovery LM MacLean, J Thomas, MD Lewis, I Cotillo, DW Gray, M De Rycker PLoS neglected tropical diseases 12 (7), e0006612, 2018 | 87 | 2018 |
| GW627368X ((N‐{2‐[4‐(4, 9‐diethoxy‐1‐oxo‐1, 3‐dihydro‐2H‐benzo [f] isoindol‐2‐yl) phenyl] acetyl} benzene sulphonamide): a novel, potent and selective prostanoid EP4 receptor … RJ Wilson, GMP Giblin, S Roomans, SA Rhodes, KA Cartwright, VJ Shield, ... British journal of pharmacology 148 (3), 326-339, 2006 | 83 | 2006 |
| Discovery of a quinoline-4-carboxamide derivative with a novel mechanism of action, multistage antimalarial activity, and potent in vivo efficacy B Baragaña, NR Norcross, C Wilson, A Porzelle, I Hallyburton, R Grimaldi, ... Journal of medicinal chemistry 59 (21), 9672-9685, 2016 | 81 | 2016 |
| Identification of Trypanocidal Activity for Known Clinical Compounds Using a New Trypanosoma cruzi Hit-Discovery Screening Cascade M De Rycker, J Thomas, J Riley, SJ Brough, TJ Miles, DW Gray PLoS neglected tropical diseases 10 (4), e0004584, 2016 | 75 | 2016 |
| Functional pharmacology of human prostanoid EP2 and EP4 receptors RJ Wilson, SA Rhodes, RL Wood, VJ Shield, LS Noel, DW Gray, H Giles European journal of pharmacology 501 (1-3), 49-58, 2004 | 70 | 2004 |
| Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies LA Armstrong, SM Lange, V Dee Cesare, SP Matthews, RS Nirujogi, ... PloS one 16 (7), e0253364, 2021 | 68 | 2021 |
| Identifying inhibitors of inflammation: a novel high-throughput MALDI-TOF screening assay for salt-inducible kinases (SIKs) RE Heap, AG Hope, LA Pearson, KMSE Reyskens, SP McElroy, ... SLAS DISCOVERY: Advancing Life Sciences R&D 22 (10), 1193-1202, 2017 | 56 | 2017 |
| Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase SN Hewitt, DM Dranow, BG Horst, JA Abendroth, B Forte, I Hallyburton, ... ACS infectious diseases 3 (1), 34-44, 2017 | 56 | 2017 |
Manu De RyckerPrincipal Investigator, University of Dundee在 dundee.ac.uk 的电子邮件经过验证
