Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex HYH Ho, R Rohatgi, AM Lebensohn, L Ma, J Li, SP Gygi, MW Kirschner Cell 118 (2), 203-216, 2004 | 535 | 2004 |
Activation of the WAVE complex by coincident signals controls actin assembly AM Lebensohn, MW Kirschner Molecular cell 36 (3), 512-524, 2009 | 303 | 2009 |
R-spondins can potentiate WNT signaling without LGRs AM Lebensohn, R Rohatgi Elife 7, e33126, 2018 | 148 | 2018 |
Biochemical suppression of small-molecule inhibitors: a strategy to identify inhibitor targets and signaling pathway components JR Peterson, AM Lebensohn, HE Pelish, MW Kirschner Chemistry & biology 13 (4), 443-452, 2006 | 86 | 2006 |
Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling AM Lebensohn, R Dubey, LR Neitzel, O Tacchelly-Benites, E Yang, ... Elife 5, e21459, 2016 | 59 | 2016 |
R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling R Dubey, P van Kerkhof, I Jordens, T Malinauskas, GV Pusapati, ... Elife 9, e54469, 2020 | 50 | 2020 |
Chromatin-remodeling complex SWI/SNF controls multidrug resistance by transcriptionally regulating the drug efflux pump ABCB1 R Dubey, AM Lebensohn, Z Bahrami-Nejad, C Marceau, M Champion, ... Cancer research 76 (19), 5810-5821, 2016 | 45 | 2016 |
In vitro reconstitution of cdc42‐mediated actin assembly using purified components HYH Ho, R Rohatgi, AM Lebensohn, MW Kirschner Methods in enzymology 406, 174-190, 2006 | 16 | 2006 |
Cdc42 and PI (4, 5) P2‐Induced Actin Assembly in Xenopus Egg Extracts AM Lebensohn, L Ma, HYH Ho, MW Kirschner Methods in enzymology 406, 156-173, 2006 | 14 | 2006 |
The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling VH Ng, Z Spencer, LR Neitzel, A Nayak, MA Loberg, C Shen, SN Kassel, ... Nature Communications 14 (1), 6173, 2023 | 11 | 2023 |
Le Ma; Li, J.; Gygi, SP; Kirschner, MW Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex HY Ho, R Rohatgi, AM Lebensohn Cell 118 (2), 203-216, 2004 | 11 | 2004 |
Receptor control by membrane-tethered ubiquitin ligases in development and tissue homeostasis AM Lebensohn, JF Bazan, R Rohatgi Current topics in developmental biology 150, 25-89, 2022 | 10 | 2022 |
Oxysterol derivatives Oxy186 and Oxy210 inhibit WNT signaling in non-small cell lung cancer LY Tang, M Spezia, T Chen, JH Shin, F Wang, F Stappenbeck, ... Cell & Bioscience 12 (1), 119, 2022 | 5 | 2022 |
The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6 ZT Spencer, VH Ng, H Benchabane, GS Siddiqui, D Duwadi, B Maines, ... Nature Communications 14 (1), 6174, 2023 | 4 | 2023 |
Direct ionic stress sensing and mitigation by the transcription factor NFAT5 CB Khandwala, P Sarkar, HB Schmidt, M Ma, M Kinnebrew, GV Pusapati, ... bioRxiv, 2023 | 2 | 2023 |
The ubiquitin ligase HUWE1 enhances WNT signaling by antagonizing destruction complex-mediated β-catenin degradation and through a mechanism independent of β-catenin stability JK McKenna, Y Wu, P Sonkusre, R Chari, AM Lebensohn bioRxiv, 2024 | | 2024 |
Discovery of gene regulatory elements through a new bioinformatics analysis of haploid genetic screens BB Patel, AM Lebensohn, GV Pusapati, JE Carette, J Salzman, R Rohatgi Plos one 14 (1), e0198463, 2019 | | 2019 |
R-spondins can potentiate WNT signaling without LGR receptors AM Lebensohn, R Rohatgi bioRxiv, 198572, 2017 | | 2017 |
Biochemical studies on the regulation of actin assembly by N-WASP and WAVE protein complexes AM Lebensohn Harvard University, 2009 | | 2009 |
The ubiquitin ligase HUWE1 enhances WNT signaling by antagonizing destruction complex JK McKenna, Y Wu, P Sonkusre, AM Lebensohn | | |