The future of aminoglycosides: the end or renaissance? JL Houghton, KD Green, W Chen, S Garneau‐Tsodikova ChemBioChem 11 (7), 880-902, 2010 | 243 | 2010 |
AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism [S] SL Pinkosky, S Filippov, RAK Srivastava, JC Hanselman, CD Bradshaw, ... Journal of lipid research 54 (1), 134-151, 2013 | 225 | 2013 |
18F-Based Pretargeted PET Imaging Based on Bioorthogonal Diels–Alder Click Chemistry JP Meyer, JL Houghton, P Kozlowski, D Abdel-Atti, T Reiner, ... Bioconjugate chemistry 27 (2), 298-301, 2016 | 151 | 2016 |
Site-specifically labeled CA19. 9-targeted immunoconjugates for the PET, NIRF, and multimodal PET/NIRF imaging of pancreatic cancer JL Houghton, BM Zeglis, D Abdel-Atti, R Aggeler, R Sawada, BJ Agnew, ... Proceedings of the National Academy of Sciences 112 (52), 15850-15855, 2015 | 114 | 2015 |
Underscoring the influence of inorganic chemistry on nuclear imaging with radiometals BM Zeglis, JL Houghton, MJ Evans, N Viola-Villegas, JS Lewis Inorganic chemistry 53 (4), 1880-1899, 2014 | 111 | 2014 |
Establishment of the In Vivo Efficacy of Pretargeted Radioimmunotherapy Utilizing Inverse Electron Demand Diels-Alder Click Chemistry JL Houghton, R Membreno, D Abdel-Atti, KM Cunanan, S Carlin, ... Molecular cancer therapeutics 16 (1), 124-133, 2017 | 100 | 2017 |
Pretargeted immuno-PET of pancreatic cancer: overcoming circulating antigen and internalized antibody to reduce radiation doses JL Houghton, BM Zeglis, D Abdel-Atti, R Sawada, WW Scholz, JS Lewis Journal of Nuclear Medicine 57 (3), 453-459, 2016 | 100 | 2016 |
Exploring the substrate promiscuity of drug‐modifying enzymes for the chemoenzymatic generation of N‐acylated aminoglycosides KD Green, W Chen, JL Houghton, M Fridman, S Garneau‐Tsodikova ChemBioChem 11 (1), 119-126, 2010 | 87 | 2010 |
Unexpected N-acetylation of capreomycin by mycobacterial Eis enzymes JL Houghton, KD Green, RE Pricer, AS Mayhoub, S Garneau-Tsodikova Journal of antimicrobial chemotherapy 68 (4), 800-805, 2013 | 72 | 2013 |
Chemical and structural insights into the regioversatility of the aminoglycoside acetyltransferase Eis JL Houghton, T Biswas, W Chen, OV Tsodikov, S Garneau‐Tsodikova ChemBioChem 14 (16), 2127-2135, 2013 | 61 | 2013 |
The structural basis for substrate versatility of chloramphenicol acetyltransferase CATI T Biswas, JL Houghton, S Garneau‐Tsodikova, OV Tsodikov Protein Science 21 (4), 520-530, 2012 | 60 | 2012 |
Challenges of pancreatic cancer J Dimastromatteo, JL Houghton, JS Lewis, KA Kelly The Cancer Journal 21 (3), 188-193, 2015 | 54 | 2015 |
Dual-modality imaging of prostate cancer with a fluorescent and radiogallium-labeled gastrin-releasing peptide receptor antagonist H Zhang, P Desai, Y Koike, J Houghton, S Carlin, N Tandon, K Touijer, ... Journal of Nuclear Medicine 58 (1), 29-35, 2017 | 48 | 2017 |
Tacrine-mefenamic acid hybrids for inhibition of acetylcholinesterase JJ Bornstein, TJ Eckroat, JL Houghton, CK Jones, KD Green, ... MedChemComm 2 (5), 406-412, 2011 | 44 | 2011 |
Preloading with Unlabeled CA19.9 Targeted Human Monoclonal Antibody Leads to Improved PET Imaging with 89Zr-5B1 JL Houghton, D Abdel-Atti, WW Scholz, JS Lewis Molecular Pharmaceutics 14 (3), 908-915, 2017 | 42 | 2017 |
Biochemical and structural analysis of aminoglycoside acetyltransferase Eis from Anabaena variabilis RE Pricer, JL Houghton, KD Green, AS Mayhoub, S Garneau-Tsodikova Molecular BioSystems 8 (12), 3305-3313, 2012 | 41 | 2012 |
Tumor-specific Zr-89 immuno-PET imaging in a human bladder cancer model FE Escorcia, JM Steckler, D Abdel-Atti, EW Price, SD Carlin, WW Scholz, ... Molecular imaging and biology 20, 808-815, 2018 | 27 | 2018 |
ImmunoPET predicts response to Met-targeted radioligand therapy in models of pancreatic cancer resistant to Met kinase inhibitors FE Escorcia, JL Houghton, D Abdel-Atti, PR Pereira, A Cho, NT Gutsche, ... Theranostics 10 (1), 151, 2020 | 25 | 2020 |
Dissecting the cosubstrate structure requirements of the Staphylococcus aureus aminoglycoside resistance enzyme ANT (4′) VR Porter, KD Green, OE Zolova, JL Houghton, S Garneau-Tsodikova Biochemical and biophysical research communications 403 (1), 85-90, 2010 | 21 | 2010 |
Current landscape in clinical pretargeted radioimmunoimaging and therapy VIJ Jallinoja, JL Houghton Journal of Nuclear Medicine 62 (9), 1200-1206, 2021 | 20 | 2021 |