| Fungal ribotoxins: molecular dissection of a family of natural killers J Lacadena, E Álvarez-García, N Carreras-Sangrà, E Herrero-Galán, ... FEMS microbiology reviews 31 (2), 212-237, 2007 | 176 | 2007 |
| Characterization of the Antifungal Protein Secreted by the MouldAspergillus giganteus J Lacadena, AM del Pozo, M Gasset, B Patino, R Campos-Olivas, ... Archives of biochemistry and biophysics 324 (2), 273-281, 1995 | 137 | 1995 |
| NMR solution structure of the antifungal protein from Aspergillus giganteus: evidence for cysteine pairing isomerism R Campos-Olivas, M Bruix, J Santoro, J Lacadena, A Martinez del Pozo, ... Biochemistry 34 (9), 3009-3021, 1995 | 106 | 1995 |
| The highly refined solution structure of the cytotoxic ribonuclease α-sarcin reveals the structural requirements for substrate recognition and ribonucleolytic activity JM Pérez-Cañadillas, J Santoro, R Campos-Olivas, J Lacadena, ... Journal of molecular biology 299 (4), 1061-1073, 2000 | 90 | 2000 |
| Characterization of pKa Values and Titration Shifts in the Cytotoxic Ribonuclease α-Sarcin by NMR. Relationship between Electrostatic Interactions, Structure, and … JM Pérez-Cañadillas, R Campos-Olivas, J Lacadena, AM del Pozo, ... Biochemistry 37 (45), 15865-15876, 1998 | 88 | 1998 |
| Fungal ribotoxins: a review of potential biotechnological applications M Olombrada, R Lázaro-Gorines, JC López-Rodríguez, ... Toxins 9 (2), 71, 2017 | 86 | 2017 |
| Overproduction and purification of biologically active native fungal α-sarcin in Escherichia coli J Lacadena, AM del Pozo, JL Barbero, JM Mancheño, M Gasset, ... Gene 142 (1), 147-151, 1994 | 77 | 1994 |
| Role of histidine‐50, glutamic acid‐96, and histidine‐137 in the ribonucleolytic mechanism of the ribotoxin α‐sarcin J Lacadena, Á Martínez del Pozo, A Martínez‐Ruiz, JM Pérez‐Cañadillas, ... Proteins: Structure, Function, and Bioinformatics 37 (3), 474-484, 1999 | 72 | 1999 |
| RNase U2 and α-sarcin: A study of relationships A Martínez-Ruiz, L García-Ortega, R Kao, J Lacadena, M Oñaderra, ... Methods in Enzymology 341, 335-351, 2001 | 67 | 2001 |
| Anomalous electrophoretic behavior of a very acidic protein: ribonuclease U2 L García‐Ortega, V De los Ríos, A Martínez‐Ruiz, M Oñaderra, ... Electrophoresis 26 (18), 3407-3413, 2005 | 61 | 2005 |
| Translocation of α-sarcin across the lipid bilayer of asolectin vesicles M Oñaderra, JM Mancheño, M Gasset, J Lacadena, G Schiavo, ... Biochemical journal 295 (1), 221-225, 1993 | 58 | 1993 |
| The insecticidal protein hirsutellin A from the mite fungal pathogen Hirsutella thompsonii is a ribotoxin E Herrero‐Galán, J Lacadena, A Martinez del Pozo, DG Boucias, N Olmo, ... Proteins: Structure, Function, and Bioinformatics 72 (1), 217-228, 2008 | 57 | 2008 |
| Secretion of Recombinant Pro-and Mature Fungal α-Sarcin Ribotoxin by the Methylotrophic YeastPichia pastoris: The Lys–Arg Motif Is Required for Maturation A Martı́nez-Ruiz, AM del Pozo, J Lacadena, JM Mancheno, M Onaderra, ... Protein expression and purification 12 (3), 315-322, 1998 | 55 | 1998 |
| The cytotoxin α‐sarcin behaves as a cyclizing ribonuclease J Lacadena, A Martı́nez del Pozo, V Lacadena, A Martı́nez-Ruiz, ... FEBS letters 424 (1-2), 46-48, 1998 | 51 | 1998 |
| Production and characterization of a colon cancer-specific immunotoxin based on the fungal ribotoxin α-sarcin N Carreras-Sangra, J Tomé-Amat, L García-Ortega, CA Batt, M Onaderra, ... Protein Engineering, Design & Selection 25 (8), 425-435, 2012 | 50 | 2012 |
| α-Sarcin, a ribosome-inactivating protein that translocates across the membrane of phospholipid vesicles M Gasset, JM Mancheño, J Lacadena, J Turnay, N Olmo, MA Lizarbe, ... Curr Top Pept Protein Res 1, 99-104, 1994 | 48 | 1994 |
| Structural basis for the catalytic mechanism and substrate specificity of the ribonuclease α‐sarcin R Campos-Olivas, M Bruix, J Santoro, A Martínez del Pozo, J Lacadena, ... FEBS letters 399 (1-2), 163-165, 1996 | 46 | 1996 |
| Substitution of histidine-137 by glutamine abolishes the catalytic activity of the ribosome-inactivating protein α-sarcin J Lacadena, JM Mancheño, A Martinez-Ruiz, A Martínez del Pozo, ... Biochemical journal 309 (2), 581-586, 1995 | 45 | 1995 |
| Characterization of a natural larger form of the antifungal protein (AFP) from Aspergillus giganteus A Martı́nez-Ruiz, AM del Pozo, J Lacadena, JM Mancheño, M Oñaderra, ... Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1997 | 44 | 1997 |
| Efficient in vivo antitumor effect of an immunotoxin based on ribotoxin α-sarcin in nude mice bearing human colorectal cancer xenografts J Tomé-Amat, M Olombrada, J Ruiz-de-la-Herrán, E Pérez-Gómez, ... Springerplus 4, 1-10, 2015 | 43 | 2015 |
