A randomized phase II preoperative study of autophagy inhibition with high-dose hydroxychloroquine and gemcitabine/nab-paclitaxel in pancreatic cancer patients HJ Zeh, N Bahary, BA Boone, AD Singhi, JL Miller-Ocuin, DP Normolle, ... Clinical cancer research 26 (13), 3126-3134, 2020 | 169 | 2020 |
Chloroquine reduces hypercoagulability in pancreatic cancer through inhibition of neutrophil extracellular traps BA Boone, P Murthy, J Miller-Ocuin, WR Doerfler, JT Ellis, X Liang, ... BMC cancer 18, 1-12, 2018 | 156 | 2018 |
The NLRP3 inflammasome and bruton's tyrosine kinase in platelets co-regulate platelet activation, aggregation, and in vitro thrombus formation P Murthy, F Durco, JL Miller-Ocuin, T Takedai, S Shankar, X Liang, X Liu, ... Biochemical and biophysical research communications 483 (1), 230-236, 2017 | 88 | 2017 |
Enhanced neutrophil extracellular trap formation in acute pancreatitis contributes to disease severity and is reduced by chloroquine P Murthy, AD Singhi, MA Ross, P Loughran, P Paragomi, GI Papachristou, ... Frontiers in immunology 10, 28, 2019 | 86 | 2019 |
Prognostic value of the systemic immune-inflammation index (SII) after neoadjuvant therapy for patients with resected pancreatic cancer P Murthy, MS Zenati, AI Al Abbas, CJ Rieser, N Bahary, MT Lotze, HJ Zeh, ... Annals of surgical oncology 27, 898-906, 2020 | 72 | 2020 |
Making cold malignant pleural effusions hot: driving novel immunotherapies P Murthy, CN Ekeke, KL Russell, SC Butler, Y Wang, JD Luketich, ... Oncoimmunology 8 (4), e1554969, 2019 | 57 | 2019 |
TLR4-dependent upregulation of the platelet NLRP3 inflammasome promotes platelet aggregation in a murine model of hindlimb ischemia S Vogel, P Murthy, X Cui, MT Lotze, HJ Zeh III, U Sachdev Biochemical and biophysical research communications 508 (2), 614-619, 2019 | 33 | 2019 |
The platelet NLRP3 inflammasome is upregulated in a murine model of pancreatic cancer and promotes platelet aggregation and tumor growth BA Boone, P Murthy, JL Miller-Ocuin, X Liang, KL Russell, P Loughran, ... Annals of hematology 98, 1603-1610, 2019 | 23 | 2019 |
Defining best practices for tissue procurement in immuno-oncology clinical trials: consensus statement from the Society for Immunotherapy of Cancer Surgery Committee B Gastman, PK Agarwal, A Berger, G Boland, S Broderick, LH Butterfield, ... Journal for immunotherapy of cancer 8 (2), 2020 | 20 | 2020 |
Different measures of HMGB1 location in cancer immunology CM Gorgulho, P Murthy, L Liotta, V Espina, MT Lotze Methods in Enzymology 629, 195-217, 2019 | 16 | 2019 |
Intrapleural interleukin-2–expressing oncolytic virotherapy enhances acute antitumor effects and T-cell receptor diversity in malignant pleural disease CN Ekeke, KL Russell, P Murthy, ZS Guo, AC Soloff, D Weber, W Pan, ... The Journal of thoracic and cardiovascular surgery 163 (4), e313-e328, 2022 | 15 | 2022 |
Platelet Btk is required for maintaining lung vascular integrity during murine pneumococcal pneumosepsis APNA de Porto, TAM Claushuis, LEH van der Donk, R de Beer, ... Thrombosis and haemostasis 119 (06), 930-940, 2019 | 10 | 2019 |
Sequestsome-1/p62-targeted small molecules for pancreatic cancer therapy J Cuyler, P Murthy, NG Spada, TF McGuire, MT Lotze, XQ Xie Drug Discovery Today 27 (1), 362-370, 2022 | 7 | 2022 |
Chloroquine reduces neutrophil extracellular trap (NET) formation through inhibition of peptidyl arginine deiminase 4 (PAD4) AD Ivey, B Matthew Fagan, P Murthy, MT Lotze, HJ Zeh III, LA Hazlehurst, ... Clinical and Experimental Immunology 211 (3), 239-247, 2023 | 6 | 2023 |
Acute pancreatitis induces a transient hypercoagulable state in murine models P Rao, B Niemann, B Szeligo, AD Ivey, P Murthy, CR Schmidt, BA Boone Pancreatology 23 (3), 306-313, 2023 | 4 | 2023 |
HMGB1 promotes myeloid egress and limits lymphatic clearance of malignant pleural effusions AC Soloff, KE Jones, AA Powers, P Murthy, Y Wang, M Byrne-Steele, ... Frontiers in Immunology 11, 532090, 2020 | 4 | 2020 |
ASO Author Reflections: Systemic Immune-Inflammation Index (SII) as a Biomarker of Response to Neoadjuvant Therapy in Patients with Pancreatic Adenocarcinoma P Murthy, BA Boone Annals of surgical oncology 27 (3), 907-908, 2020 | 4 | 2020 |
Intratumoral T cell clonality and survival in a randomized phase II study of preoperative autophagy inhibition in combination with gemcitabine and nab-paclitaxel treatment in … P Murthy, D Weber, SN Sharma, AD Singhi, N Bahary, W Pan, ... Journal of Clinical Oncology 39 (15_suppl), e16001-e16001, 2021 | 3 | 2021 |
Baseline plasma inflammatory profile is associated with response to neoadjuvant chemotherapy in patients with pancreatic adenocarcinoma A Chopra, R Zamora, Y Vodovotz, JC Hodges, D Barclay, R Brand, ... Journal of Immunotherapy 44 (5), 185-192, 2021 | 2 | 2021 |
Gut microbiota composition and outcomes following neoadjuvant therapy in patients with localized pancreatic cancer: A prospective biomarker study. P Murthy, K Li, RR Anderko, AD Singhi, A DeSilva, A Chopra, ... Journal of Clinical Oncology 40 (16_suppl), 4143-4143, 2022 | 1 | 2022 |